Chapter 31 - 32 - Cellular And Molecular Effects Of Radiation Exposure Flashcards
What are the 3 main radiation effects on macromolecules?
Main chain scissor
Cross linking
Point lesions
A separation involving the main linkage or chain of atoms in a large molecule
Main chain scission
Formation of new chemical bonds that link side-chains with one another
Cross-linking
What results and may be used as a measure of the degree of main chain scission?
Reduced viscosity
What is the result of cross-linking?
Increased viscosity of a macro molecular solution
Disruption or alteration of single chemical bonds. Changes in the cell may be undetectable to the repair mechanisms of intracellular environment. The cell will be damaged but may survive and reproduce the error. Though to be the mechanism of injury for late effects of radiation
Point lesions
What is the most important macromolecule of the cell?
DNA
_____ ____ from radiation may be detected and repaired
Chromosomal aberrations