Chapter 3 Flashcards
1
Q
Biotransformation
A
Biochemical changes that occur to the drug within the body, usually resulting in the breakdown and inactivation of the drug (SYN: drug metabolism)
2
Q
Clearance
A
The process by which the active form of the drug is removed from the bloodstream by either metabolism or excretion
3
Q
Drug Microsomal Metabolizing System (DMMS)
A
A series of enzymes located on the smooth endo-plasmic reticulum that are important in catalyzing drug biotransformation
4
Q
Half-Life
A
The time required to eliminate 50% of the drug existing in the body
5
Q
Metabolite
A
The compound that is formed when the drug undergoes biotransformation and is chemically altered by some metabolic process
