Chapter 3

Question 0

Antagonist

Answer 0

Substance that binds to a receptor and interferes/prevents the action of the transmitter

Question 1

Agonist

Answer 1

A substance that binds to a receptor and initiates a response like that of a endogenous ligand

Question 2

Up regulation

Answer 2

Compensatory increase in receptor availability at the synapse of the neuron

Question 3

Down regulation

Answer 3

Compensatory reduction in receptor availability

Question 4

Inotropic receptor

Answer 4

A receptor that includes an ion channel.

-opened when receptor is bound to particular ligand

Question 5

Ligand gated ion channel

Answer 5

Opens/closes in response to a particular ligand

Question 6

Metabotropic receptor

Answer 6

Receptor without an ion channel

-when activated uses a g protein system to alter function in post synaptic neuron

Question 7

G protein

Answer 7

Resides in intracellular portion of receptor

• activated when ligand binds to a receptor
• part of 2nd messenger system

Question 8

Degradation

Answer 8

Enzymatic breakdown pf NT’s into inactive metabolites

Question 9

Reuptake

Answer 9

Process by which NT’s in synaptic cleft are taken ip by transporters

Question 10

Transporters

Answer 10

Specialized receptors in presynaptic membrane/glia that recognize NT’s and return them for use