chapter 3๐๐ Flashcards
5โ to 3โ
The direction of synthesis on a nucleotide strand
amino acid
An organic compound that is a building block within a polypeptide or protein
Anticodon
A set of three consecutive nucleotides that is part of a tRNA molecule and is complementary to a codon; the three nucleotides consist of any of the four bases adenine, uracil, guanine or cytosine
Apoptosis
A programmed series of events that leads to cell death (as a result of the dismantling of the internal contents of the cell by various enzymes, including caspases)
Cellular machineryโ
Biological machinesโ that work to manufacture a biological molecule; e.g. transcription machinery includes RNA polymerase and binding factors or proteins; the translation machine is the ribosome
Chromosome
A structure composed of DNA and protein that contains linear arrays of genes carrying genetic information; prokaryotes generally have one circular chromosome, whereas eukaryotes have a number of linear chromosomes
Coding DNA
The sections of DNA that code for a protein; they contain instructions that determine the order of the codons in the mRNA, which in turn determines the order of the amino acids in a polypeptide or protein
Codon
A set of three consecutive nucleotides found in a DNA or an mRNA molecule; it carries codes for a specific amino acid; the three nucleotides consist of any of the four bases adenine, thymine, guanine and cytosine in the case of DNA, or adenine, uracil, guanine and cytosine in the case of mRNA
Complementary base pairing
The phenomenon whereby guanine always hydrogen bonds with cytosine and adenine always hydrogen bonds with thymine; guanine and cytosine share three hydrogen bonds, and adenine and thymine share two hydrogen bonds; the complementary pairing enables the helical structure of DNA to form
DNA (deoxyribonucleic acid)
The information-containing molecule present in all living things that contains the instructions, written in a chemical code, for the production of proteins by the cell; the information it contains is sufficient for the making and maintaining the organism; in addition, DNA is the genetic material that passes this information on to the next generation
DNA helicase
An enzyme that helps the two strands of the DNA double helix unwind and separate
DNA ligase
An enzyme used to catalyse the formation of a bond between two pieces of DNA
DNA polymerase
A member of a class of enzymes found in all living things, that synthesises new strands of DNA based on a template strand and according to complementary base-pair rules; DNA polymerases are important tools in biotechnology because they are capable of making exact copies of fragments of DNA, enabling efficient and accurate amplification of DNA templates
DNA replication
The process a DNA molecule undergoes to make a complete and identical copy of itself, readying a cell for cell division; it is a semi-conservative process, and the two daughter molecules contain exact copies of the genetic material in the parent molecule
Double helix
The structure formed by double-stranded molecules of nucleic acids such as DNA; two linear strands that run opposite to each other and twist together