Chapter 27: Hypertensive Disorders in Pregnancy Flashcards
What are the 3 type of Hypertensive Disorders ?
- Gestational hypertension
- Preeclampsia
- Eclampsia
- Chronic hypertension ?
True or False: The rate of pregnancy related hypertension has risen steadily since 1990 for all ages and ethnic groups ?
True
True or False: The rate of chronic HPTN in mothers >40 is nearly 10x higher than those younger than age 20 ?
True
What things cause Maternal Morbidity ?
- Placental abruption
- Cerebral hemorrhage
- Hepatic or renal dysfunction
- DIC (disseminated intravascular coagulation)
- Pulmonary edema
- Seizures
True or False: Pregnancy-related hypertension accounts for 10% to 15% of maternal deaths worldwide ?
True
True or False: Preeclampsia accounts for more than 500,000 maternal deaths each year ?
True
Gestational hypertension is also known as what ?
Pregnancy induced hypertension
True or False: With Gestational hypertension, there are generally good outcomes for both mom and baby ?
True
Gestational Hypertension is defined as what ?
The onset of hypertension WITHOUT proteinuria
- can occur after the 20th week of pregnancy
Preeclampsia is defined as what ?
A pregnancy specific syndrome in which hypertension develops after 20 weeks of gestation in a previously normotensive woman
gestational hypertension is defined as Blood Pressure of what ?
Systolic BP > 140mmHg
Diastolic BP > 90mmHg
The diagnosis of onset of Gestational hypertension during pregnancy is based on what ?
2 measurements on 2 separate occasions, that meet criteria for gestational BP elevation within a 1-week period
Gestational hypertension USUALLY develops when ?
at or after 37 weeks of gestation
What do we know, in terms of gestational hypertension, and the patients BP before and after pregnancy ?
- Women with GH have no preexisting hypertension
- BP returns o normal within 6 weeks after birth
If a women is Dx with GH before 35 weeks, it may progress to what ?
preeclampsia
What is Preeclampsia characterized by ?
Reduced organ perfusion with presence of hypertension and proteinuria
(essentially a problem causing hypertension. may or may not have proteinuria)
What is the only known cure for Preeclampsia ?
Birth
True or False: Preeclampsia may lead to Eclampsia ?
True
What do we know about Preeclampsia, and the signs and symptoms ?
Signs & symptoms develop only during pregnancy and disappear after birth
True or False: There is no reliable method to predict Preeclampsia ?
True
What are risk factors for Preeclampsia ?
- Primigravida (pregnant for 1st time)
- Second pregnancy with a new partner/father
- Multifetal pregnancy
- Extremes of age (>40 or <19)
- Obesity
- Preexisting medical condition
(chronic HTN, renal dz, DM 1, collagen dz) - Preeclampsia in a previous pregnancy
- Family Hx of Preeclampsia
- Poor outcome in previous pregnancy
(IUGR, Fetal death)
What is the main pathophysiologic factor with Preeclampsia ?
An increase in BP, but poor perfusion resulting from vasospasm
With Preeclampsia, there is a significant decrease in placental what ?
kidney, liver and brain function
Mild Preeclampsia is characterized by what types of things ?
- BP > 140/90
- Transient headache
- Normal Liver functions
- Proteinuria
- > +1
- 24hr > 300mg
- output > 25-30cc/hr
- Reduced placental perfusion
Sever Preeclampsia is characterized what ?
- BP > 160/110
- Persistent/severe headache
- Liver functions may be altered
- Proteinuria
- > +3
- 24hrs > 5gms
- output < 400-500cc/24hrs
- Possible Epigastric pain
- Visual problems - blurred
- Pulmonary edema
- Decreased placental perfusion
- Abnormal fetus status on tests
What is Eclampsia ?
The onset of seizure activity or coma in a woman with preeclampsia
What are signs & symptoms of Eclampsia ?
- seizure activity or coma in women diagnosed with preeclampsia
- No Hx of previous seizure disorder
- Scotomata
- Blurred vision
- Epigastric pain
- Vomiting
- Persistent or severe headache
- Neurologic hyperactivity
- Pulmonary edema
- Cyanosis
What is HELP Syndrome associated with ?
Severe Preeclampsia & Liver dysfunction