Chapter 25 Elective Termination of Pregnancy Flashcards
maternal morbidity is lowest if abortion is p[erformed before 8 weeks gestation
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if gestational age is <6 weeks, verification of POC on pathology report is veyr important as embryo is so small at < 6 weeks,, d& c procedure may fail to evacuate it from the uterus.
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nonsurgical abortion: mifepristone , utilized for terminations prior to 9 weeks of gestation.
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mifeprixtone is a symthetic progesterone receptor antagonist that binds to progesterone receptors in the uterus, thus blocking the stimulatory effects of progesterone on endometrial growth.
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mifepristone thereby disrupts pregnancy by making endometrial lining of unsuitable to sustain the pregnancy. , this leads to detachment of the embryo.
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success rate of top is improved when mifeprix used with prostaglandin analog such as misoprostol (24-48 hrs later). 2 weeks later, success of completion is typically confirmed with ultrasound or serum bhcg.
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