Chapter 15 Endometriosis and Adenomyosis Flashcards
adenomyosis is
extension of endometrial tissue into uterine myometrium.
cause of adenomyosis
high levels of estrogen stimulate hyperplasia of basalis layer of endometrium. barrier between endometrium and myometrium is broken and endometrial cells then invade the myometrium.
adenomyosis causes uterus to become
diffusely enlarged and globular due to hypertrophy and hyperplasia of myometrium adjacent to ectopic endometrial tissue.
endometrial tissue in adenomyosis estends from the ___ layer of endometrium
basalis it oes not undergo proliferative and secretory changes traditionally seen in normally located endometrium / in endometriosis.
endometriosis contains both ___ and ___ endometrial tissue.
glandular and stromal.
about ___ of pts with adenomyosis also have endometriosis
15-20%
50-60% of pts with adenomyosis also have
uterine fibroids.
what is most accurate imaging tool for adenomyosis?
MRI
___ should be performed to rule out concomitant endometrial hyperplasia and cancer in women >45 before a hysterectomy is performed for adenomyosis.
endometrial biopsy.
minimal symptoms of adenomyosis may be treated with
analgesics, nsaids, ocps, or progestins, although adenomyosis is less responsive to hormonal management than endometriosis.
Levonorgestrel containing IUD is most effective temporary means of treating symptoms of adenomyosis.
true