Chapter 24 - Digestive System Flashcards
What are the major organs of the Digestive System?
Oral Cavity, Pharynx, Esophagus, Stomach, Small Intestine, Large Intestine, Teeth, Tongue, Salivary Glands, Liver, Gallbladder, Pancreas
Define Oral Cavity (Mouth)
Ingestion, mechanical digestion with accessory organs (teeth and tongue), moistening, mixing with salivary glands
Define Pharynx
Muscular propulsion of materials into the esophagus
Define Stomach
Chemical digestion of materials by acid and enzymes; mechanical digestion through muscular contractions
Define Small Intestine
Enzymatic digestion and absorption of water, organic substrates, vitamins, and ions
Define Large Intestine
Dehydration and compaction of indigestible materials in preparation for elimination
Define Teeth
Mechanical digestion by chewing (mastication)
Define Tongue
Assists mechanical digestion with teeth, sensory analysis
Define Salivary Glands
Secretion of lubricating fluid containing enzymes that break down carbohydrates
Define Liver
Secretion of bile (important for lipid digestion), storage of nutrients, many other vital functions
Define Gallbladder
Storage and concentration of bile
Define Pancreas
Exocrine cells secrete buffers and digestive enzymes; endocrine cells secrete hormones
Define Peritonitis
An inflammation of the peritoneum, the serous membrane of the abdominopelvic cavity. It is a painful condition that interferes with the normal functions of the affected organs.
What are the four types of teeth?
- Incisors
- Canines
- Premolars
- Molars
Name the parts of the tooth from deepest to the surface
Root, Neck, and Crown
Name the parts of the salivary glands
Parotid duct, openings of the sublingual ducts, frenulum of tongue, opening of the left submandibular duct, submandibular
What are the major salivary glands?
- Parotid gland
- Sublingual gland
- Submandibular gland
Define mumps
The mumps virus most often targets the major salivary glands, especially the parotid glands, but other organs can be infected. In males, mumps can infect testes and cause sterility. Infection of the pancreas by the mumps virus can produce temporary or permanent diabetes.
List the anatomy of the esophagus from thick to thin
Muscularis mucosae, lamina propria, stratified squamous epithelium
List the phases of deglutition
- Buccal Phase
- Pharyngeal Phase
- Esophageal Phase
- Bolus Enters Stomach
Define the first phase of deglutition
(Buccal Phase)
- Hard Palate
- Soft Palate
- Bolus
- Oropharynx
- Epiglottis
- Trachea
Define the second phase of deglutition
(Pharyngeal Phase)
- Uvula
- Bolus
- Epiglottis
- Larynx
Define the third phase of degluition
(Esophageal Phase)
- Peristalsis
- Trachea
- Esophagus
Define the fourth phase of deglutition
(Bolus Enters Stomach)
- Thoracic Cavity
- Lower Esophageal Sphincter
- Stomach
What are Gastritis and Peptic Ulcers?
A superficial inflammation of the gastric mucosa. Can develop after a person swallowed drugs, including alcohol and aspirin
What is the first step in the Secretion of Hydrochloric Acid Ions?
Hydrogen ions (H+) are generated inside the parietal cell as the enzyme carbonic anhydrase converts CO2 and H2O to carbonic acid (H2CO2), which then dissociates
What is the second step in the Secretion of Hydrochloric Acid Ions?
An anion countertransport mechanism ejects the bicarbonate ions into the interstitial fluid and imports chloride ions into the cells
What is the third step in the Secretion of Hydrochloric Acid Ions?
The chloride ions then diffuse across the cell and exit through open chloride channels into the lumen of the gastric glands
What is the fourth step in the Secretion of Hydrochloric Acid Ions?
The hydrogen ions are actively transported into the lumen of the gastric glands
What is Pancreatitis?
An inflammation of the pancreas. Extremely painful. The factors that may produce it include a blockage of the excretory ducts, bacterial or viral infections, ischemia, and drug reactions
What is a ketone body?
Keto acids produced during the catabolism of lipids and ketogenic amino acids; specifically, acetone, acetoacetata, and beta-hydroxybutyate
What is ketoacidosis?
A condition characterized by a decrease in blood pH due to the presence of large numbers of ketone bodies
What is the difference in an essential amino acid and a nonessential amino acid?
Amino acids come from the diet. Nonessential amino acids can be made by the body on demand.
What are the basic food groups?
- Grains
- Vegetables
- Fruits
- Dairy
- Protein
What do grains provide?
Carbohydrates: vitamins E, thiamine, niacin, folate; calcium; phosphorus, iron, sodium, dietary fiber
What do vegetables provide?
Carbohydrates; vitamins A, C, E, folate; dietary fiber; potassium
What do fruits provide?
Carbohydrates; vitamins A, C, E, folate; dietary fiber; potassium
What does dairy provide?
Complete proteins; fats; carbohydrates; calcium; potassium; magnesium; sodium; phosphorus; vitamins A, B12, pantothenic acid, thiamine, riboflavin
What does protein provide?
Complete proteins; fats; calcium; potassium; phosphorus; iron; zinc; vitamins E, thiamine, B6
What health effects do grains have?
Whole grains prevent rapid rise in blood glucose levels, and consequent rapid rise in insulin levels
What health effects do vegetables have?
Reduce risk of cardiovascular disease; protect against colon cancer (folate) and prostate cancer (lycopene in tomatoes)
What health effects do fruits have?
Reduce risk cardiovascular disease; protect against colon cancer (folate)
What health effects does dairy have?
Whole milk: high in calories, may cause weight gain; saturated fats correlated with heart disease
What health effects does protein have?
Fish and poultry lower risk of heart disease and colon cancers (compared to red meat). Consumption of up to one egg per day does not appear to increase incidence of heart disease
What are the bulk minerals?
- Sodium
- Potassium
- Chloride
- Calcium
- Phosphorus
- Magnesium
What are the trace minerals?
- Iron
- Zinc
- Copper
- Manganese
- Cobalt
- Selenium
- Chromium
What is the significance of sodium?
Major cation in body fluids; essential for normal membrane function
What is the significance of potassium?
Major cation in cytoplasm; essential for normal membrane
What is the significance of chloride?
Major anion in body fluids; functions in forming HCI
What is the significance of calcium?
Essential for normal muscle and neuron function and normal bone structure
What is the significance of phosphorus?
In high-energy compounds, nucleic acids, and bone matrix (as phosphate)
What is the significance of magnesium?
Cofactor of enzymes, required for normal membrane functions
What is the significance of iron?
Component of hemoglobin, myoglobin, and cytochromes
What is the significance of zinc?
Cofactor enzyme systems, notably carbonic anhydrase
What is the significance of copper?
Required as cofactor for hemoglobin synthesis
What is the significance of manganese?
Cofactor for some enzymes
What is the significance of cobalt?
Cofactor for transaminations, mineral in vitamin B12 (cobalamin)
What is the significance of chromium?
Cofactor for glucose metabolism
What are the fat soluble vitamins?
- A
- D
- E
- K
What are the water soluble vitamins?
- B1
- B2
- B3
- B5
- B6
- B9
- B12
- B7
- C
What is vitamin B1?
Thiamine
What is vitamin B2?
Riboflavin
What is vitamin B3?
Niacin
What is vitamin B5?
Pantothenic Acid
What is vitamin B6?
Pyridoxine
What is vitamin B9?
Folic Acid
What is vitamin B12?
Cobalamin
What is vitamin B7?
Biotin
What is vitamin C?
Ascorbic acid
What is the significance of vitamin A?
Maintains epithelia; required for synthesis of visual pigments; supports immune system; promotes growth, and bone remodeling
What is the significance of vitamin D?
Required for normal for normal bone growth, intestinal, calcium and phosphorus absorption, and retention of these ions at the kidneys
What is the significance of vitamin E?
Prevents breakdown of vitamin A and fatty acids
What is the significance of vitamin K?
Essential for liver synthesis of prothrombin and other clotting factors
What is the significance of vitamin B1 (thiamine)?
Coenzyme in many pathways
What is the significance of vitamin B2 (riboflavin)?
Part of FAD, involved in multiple pathways, including glycolysis and citric acid cycle
What is the significance of vitamin B3 (niacin)?
Part of NAD, involved in multiple pathways
What is the significance of vitamin B5 (pantothenic acid)?
Coenzyme A, in multiple pathways
What is the significance of vitamin B6 (pyridoxine)?
Coenzyme in amino acid and lipid metabolism
What is the significance of vitamin B9 (folic acid)?
Coenzyme in amino acid and nucleic and metabolism
What is the significance of vitamin B12 (cobalamin)?
Coenzyme in nucleic acid metabolism
What is the significance of vitamin B7 (biotin)?
Coenzyme in many pathways
What is the significance of vitamin C (ascorbic acid)?
Coenzyme in many pathways
What is the source of vitamin A?
Leafy green and yellow vegetables
What is the source of vitamin D?
Synthesized in skin exposed to sunlight
What is the source of vitamin E?
Meat, milk, vegetables
What is the source of vitamin K?
Vegetables; production by intestinal bacteria
What is the source of vitamin B1?
Milk, meat, bread
What is the source of vitamin B2?
Milk, meat, eggs, and cheese
What is the source of vitamin B3?
Meat, bread, potatoes
What is the source of vitamin B5?
Milk, meat
What is the source of vitamin B6?
Meat, whole grains, vegetables, orange juice, cheese, and milk
What is the source of vitamin B9?
Leafy vegetables, some fruits, liver, cereal, and bread
What is the source of vitamin B12?
Milk, meat
What is the source of vitamin B7?
Eggs, meat, vegetables
What is the source of vitamin C?
Citrus fruits
What are the effects of deficiency or excess - vitamin A?
Deficiency - retarded growth, night blindness, deterioration of epithelial membranes
Excess - Liver damage, skin paling, CNS effects (nausea, anorexia)
What are the effects of deficiency or excess - vitamin D
Deficiency - rickets, skeletal deterioration
Excess - calcium deposits in many tissues, disrupting functions
What are the effects of deficiency or excess - vitamin E
Deficiency - anemia, other problem suspected
Excess - Nausea, stomach cramps, blurred vision, fatigue
What are the effects of deficiency or excess - vitamin K
Deficiency - bleeding disorders
Excess - Liver dysfunction, jaundice
What are the effects of deficiency or excess - vitamin B1
Deficiency - Muscle weakness, CNS and cardiovascular problems, including heart disease called beriberi
Excess - Hypotension
What are the effects of deficiency or excess - vitamin B2
Deficiency - Epithelial and mucosal deterioration
Excess - Itching, tingling
What are the effects of deficiency or excess - vitamin B3
Deficiency - CNS, GI, epithelial, and mucosal deterioration; called pellagra
Excess - Itching, burning, vasodilation, death after large doses
What are the effects of deficiency or excess - vitamin B5
Deficiency - Retarded growth, CNS, disturbances
Excess - None reported
What are the effects of deficiency or excess - vitamin B6
Deficiency - Retarded growth, anemia, convulsions, epithelial changes
Excess - CNS alterations, perhaps fatal
What are the effects of deficiency or excess - vitamin B9
Deficiency - Retarded growth, anemia, gastrointestinal disorders, developmental abnormalities
Excess - Few notes, except at massive doses
What are the effects of deficiency or excess - B12
Deficiency - Impaired RBC productions, causing pernicious anemia
Excess - Polycythemia
What are the effects of deficiency or excess - B7
Deficiency - Fatigue, muscular pain, nausea, dermatitis
Excess - None reported
What are the effects of deficiency or excess - C
Deficiency - Epithelial and mucosal deterioration; called scurvy
Excess - Kidney stones
What is the recommended daily allowance (RDA) in mg of sodium?
1500 mg
Which vitamins can be found in meat?
- Vitamin E
- Vitamin B1 (thiamine)
- Vitamin B2 (riboflavin)
- Vitamin B3 (niacin)
- Vitamin B5 (pantothenic acid)
- Vitamin B6 (pyridoxine)
- Vitamin B12 (colalamin)
- Vitamin B7 (biotin)
Which vitamins can be found in vegetables?
- Vitamin A
- Vitamin E
- Vitamin K
- Vitamin B6 (pyridoxine)
- Vitamin B9 (folic acid)
- Vitamin B7 (biotin)
Which vitamins can be found in milk?
- Vitamin E
- Vitamin B1 (thiamine)
- Vitamin B2 (riboflavin)
- Vitamin B5 (pantothenic acid)
- Vitamin B6 (pyridoxine)
- Vitamin B12 (cobalamin)
Scurvy can result from deficiency of ______________.
Vitamin C
Beriberi can result from deificiency of ____________.
Vitamin B1 (thiamine)
Pernicious anemia can result from deficiency of ___________.
Iron
Goiter can result from deficiency of ___________.
Iodine
An overdose of vitamins can result in a condition called _______________.
Hypervitaminosis
What is a fever?
A fever is a body temperature greater than 37.2 *C (99 *F)
The technical word for “chewing” is
mastication
The technical word for “swallowing” is
deglutition
What are the 4 muscles of mastication
A. Masseter
B. Temporalis
C. Later pterygoid
D. Medial pterygoid
The _____________ and ____________ bones from the hard palate.
Maxillary and palatine
The structure regulates the flow of chyme into the small intestine from the stomach. It is the ___________
ileocecal sphincter
This structure is responsible for the chemical breakdown of materials via acid and enzymes; mechanical processing through muscular contractions _________________.
Stomach
This cranial nerve controls the activity of many digestive structures _____________ # ______.
Vagus nerve and #X
What are the 4 parts of the stomach?
A. Fundus
B. Body
C. Cardia
D. Pylorus
What are the 3 phases of gastric activity?
- Cephalic
- Gastric
- Intestinal
Define lumen
The central space within a duct or other internal passageway
Define interstitial fluid
The fluid in the tissues that fills the spaces between cells
Bile is produced in the _________. Bile breaks down ___________.
- Liver
- Lipids
Bile release from the gallbladder into the duodenum occurs only under the stimulation of ___________.
Chloecystokinin (CCK)
Trace the flow of bile in someone who has had their gall bladder removed
- Liver
- Right Hepatic Duct
- Left Hepatic Duct
- Common Hepatic Duct
- Common Bile Duct
- Spincter of Oddi = Hepatopancreatic sphincter
- Duodenal ampulla
- Duodenal papilla
- Duodenum
N/A - Pancreatic duct & cystic duct
Where is secretin produced?
Intestinal tract
Where is vasoactive intestinal peptide produced?
Duodenum
Where is gastric inhibitory peptide (GIP) produced?
Duodenum
Where is CCK produced?
Intestinal tract
Where is salivary amylase produced?
Parotid glands
____________ is a glycoprotein required for the absorption of vitamin B12 in the small intestine.
Intrinsic factor
___________ is an enzyme that breaks down proteins in the stomach.
Pepsin
What are the 3 parts of the small intestine?
- Jejunum
- Ileum
- Duodenum
Peyer’s patches are found in the ________.
Ileum
Bacteria in the large intestines supply us with 3 vitamins. Identify them.
A. Vitamin K
B. Biotin
C. Vitamin B5
Trace a piece of pizza
- Oral cavity
- Esophagus
- Esophageal (cardiac) sphincter
- Stomach
- Pyloric sphincter
- Duodenum
- Jejunum
- Ileum
- Ileocecal valve
- Cecum
- Ascending colon
- Hepatic (right colic) flexure
- Transverse colon
- Splenic (left colic) flexure
- Descending colon
- Sigmoid colon
- Rectum
- Anus
N/A - Liver, pancreas, common bile duct, spleen