Chapter 23: Cardiovascular Dysfunction Flashcards

1
Q

What is the 2nd biggest cause of death for the first year of life?

A

congenital heart disease (prematurity is 1st)

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2
Q

What is the most common cardiac anomaly in pediatrics?

A

ventricular septal defect

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3
Q

What are the 3 major changes to fetal circulation that take place at birth?

A

– when a newborn takes first breath, 3 abrupt changes:
1. change from fetal circulation (with umbilical vein and umbilical arteries) to postnatal circulation
2. closure of foramen ovale – d/t pressure in L atrium > pressure in R atrium
3. beginning of closure of ductus arteriosus – d/t increased oxygen

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4
Q

What are the 4 categories of cardiac defects?

A
  1. acyanotic
  2. obstructive
  3. cyanotic
  4. acquired
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5
Q

What are acyanotic heart defects?

A
  • AKA increased pulmonary blood flow defects
  • L to R shunt –> increased volume on R side of heart –> R side hypertrophy and increased blood flow to lungs
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6
Q

What are the 3 acyanotic defects?

A
  1. atrial septal
  2. ventricular septal
  3. patent ductus arteriosus
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7
Q

What is an atrial septal defect (ASD)?

3 aspects

A
  • opening in septum between L and R atria –> causes mixing of oxygenated and deoxygenated blood
  • s/s:
    – usually asymptomatic
    – can develop CHF
  • treatments:
    – surgical repair
    – cardiac catheter in early childhood
    – can close spontaenously
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8
Q

What is a ventricular septal defect (VSD)?

4 aspects

A
  • opening in septum between L and R ventricles –> causes mixing of oxygenated and deoxygenated blood
  • more common than ASD
  • s/s:
    – commonly causes CHF
    – may be asymptomatic, but depends on size
  • treatments:
    – surgical repair
    – cardiac catheter
    – sponatenous closing if small
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9
Q

What is a patent ductus arteriosus (PDA)?

3 aspects

A
  • ductus arteriosus (shunt between ascending aorta and pulmonary artery) fails to close after birth –> causes shunting to pulmonary artery and increased fluid to lungs and L side of heart
  • s/s:
    – murmur
    – bounding pulses
    – may be asymptomatic
    – can have signs of CHF
  • treatments:
    – meds: indomethicin or ibuprofen (only ibuprofen is clinically indicated for PDA closure, but both are used)
    – PDA ligation using cardiac catheter
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10
Q

What are obstructive heart defects?

A

oxygenated blood is unable to flow to the rest of the body

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11
Q

What are the 4 types of obstructive defects?

A
  1. coarctation of the aorta
  2. aortic stenosis
  3. pulmonic stenosis
  4. hypoplastic left heart syndrome (HLHS)
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12
Q

What is a coarctation of the aorta?

4 aspects

A
  • narrowing of the aorta –> causes restricted amount of oxygenated blood that travels to the rest of the body
  • varying degrees of narrowing can occur
  • s/s:
    – increased pressure in upper extremities (BP, bounding pulses, warm) and decreased pressure in lower extremities (BP, weak pulses, cool)
    – signs of CHF
    – at risk for aneurysm or stroke
  • treatments:
    – surgical repair
    – cardiac catheter
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13
Q

What is aortic stenosis?

3 aspects

A
  • narrowing or fusion of the aortic valves –> causes decreased L ventricular outflow and L side hypertrophy
  • s/s:
    – L side HF
    – pulmonary edema
  • treatment:
    – surgical repair
    – cardiac catheter
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14
Q

What is pulmonic stenosis?

3 aspects

A
  • stiffening of pulmonic valve –> causes R ventricular hypertrophy and decreased pulmonary blood flow d/t resistance
  • this is often a component of tetralogy of Fallot
  • s/s:
    – can be asymptomatic
    – cyanosis
    – CHF
    – at risk for developing endocarditis
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14
Q

What is hypoplastic left-sided heart syndrome (HLHS)?

4 aspects

A
  • L side of heart is underdeveloped –> restriction of blood flow to rest of body
  • higher mortality rates
  • s/s:
    – mild cyanosis, but death will occur if not treated/ductal closure not prevented
  • treatment:
    – maintenance of patent ductus arteriosus (PDA) to allow oxygenated blood from R ventricle to enter aorta to flow to rest of body
    – maintenance of patent foramen ovale (ASD) to improve mixing of oxygenated and deoxygenated blood in R atria –> R ventricle can help pump oxygenated blood to aorta via PDA
    – surgery
    – heart transplant
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15
Q

What are cyanotic heart defects?

A

cardiac anomaly where oxygenated blood entering aorta is mixed with deoxygenated blood

16
Q

What are the 2 types of cyanotic defects?

A
  1. tetralogy of Fallot
  2. transposition of the great arteries
17
Q

What is tetralogy of Fallot (TOF)?

3 aspects

A
  • condition involving 4 congenital defects:
    VSD – allows mixing of oxygenated and deoxygenated blood
    pulmonic stenosis – decreases blood flow to lungs
    overriding aorta – aortic valve sits right above ventricular septal defect (VSD), further allowing mixing of oxygenated and deoxygenated blood when entering aorta from both ventricles
    R ventricular hypertrophy
  • s/s:
    – cyanosis that may progress
    – murmur
    – tet/blue spells – acute episodes of cyanosis and hypoxia
    – clubbing of fingers
    – poor growth – FTT
    – fatigue
  • treatments:
    – surgery
    – squatting positions (knee-to-chest) – for tet spells; decreases return of systemic venous blood to heart
18
Q

What is transposition of the great arteries (TGA)?

4 aspects

A
  • aorta and pulmonary artery are attached to opposite chambers of the heart (aorta to R ventricle, pulmonary artery to L ventricle), creating 2 completely separate circulations
  • not sustainable with life unless mixing of blood is established
  • s/s:
    – rapid/labored breathing
    – tachycardia
    – cool, clammy skin
    – cyanosis
    – cardiomegaly
  • treatments:
    – surgery – switch procedure
    – balloon atrial septostomy
    – prostaglandin E – keeps foramen ovale/PDA open to allow blood mixing
19
Q

What are acquired heart defects/diseases?

A

heart anomalies that the child was not born with; includes infectious and inflammatory disorders

20
Q

What are the 6 types of acquired heart defects/diseases?

A
  1. CHF
  2. endocarditis
  3. rheumatic fever
  4. Kawasaki disease
  5. hyperlipidemia
  6. hypertension
21
Q

What is Kawasaki disease?

3 aspects

A
  • inflammation of blood vessels throughout the body and surrounding the heart
  • s/s:
    – fever lasting 5+ days
    – rash
    – red bloodshot eyes
    – bright red, swollen, cracked lips
    – strawberry tongue
    – swollen hands and feet
    – redness on palms and soles of feet
    – swollen lymph nodes
  • treatments:
    – aspirin (ASA) – for fever and inflammation (usually contraindicated in peds d/t Reyes)
    – IV immunoglobulin
    – antiplatelets
    – Remicade – for inflammation