Chapter 22 (Pentose Phosphate Pathway)

Question 1

The pentose phosphate pathway is a source of ___ and ___

Answer 1

NADPH (used in reductive biosynthesis)

Ribose-5P

Question 2

Tissues most heavily involved in ___ are rich in pentose phosphate pathways

Answer 2

lipid biosynthesis

Question 3

The overall reaction of the pentose phosphate pathway

Answer 3

3 G-6P + 6 NADP + 3 H2O (arrow) 6 NADPH + 3 CO2 + 2 F-6P + GAP

Question 4

___ is the most common enzyme that is deficient

Answer 4

Glucose-6-phosphate Dehydrogenase

better resistance to malaria

Question 5

Transketolase

Answer 5

Transfers two carbon units

Requires TPP

Question 6

Transaldolase

Answer 6

Transfers three carbon units
Uses a Lysine active site
Creates a Schiff Base

Question 7

What happens when we eat foods with high carbohydrates

Answer 7

We increase the amount of Xylulose-5P
This increases the flux through the Pentose phosphate pathway and stimulates increased glycolysis
This increases the amount of NADPH and Acetyl-CoA which are used to synthesis fatty acid biosynthesis