Chapter 20: Pharmacology Flashcards
The nurse is caring for a patient newly diagnosed with hypertension. Blood pressure readings over the past 8 hours have been:08:00: 164/93 mm Hg12:00: 158/90 mm Hg16:00: 166/94 mm HgThe health care provider prescribes a no added salt diet and plans to start the patient on hydrochlorothiazide 25 mg. Which action is most important for the nurse to do before administering this drug?
- Check the patient’s serum potassium level.
- Review the patient’s urine output for the past 24 hours.
- Instruct the unlicensed assistive personnel to check the patient’s blood pressure.
- Check whether the patient is having abnormal heart rhythms.
Ans: 1
Hydrochlorothiazide is a thiazide diuretic often used to treat hypertension. An adverse effect of these diuretics is that when Na+ reabsorption is blocked by thiazide diuretics, this increases Na+ delivery to the cortical collecting duct and increases Na+ reabsorption in this segment of the nephron. Because Na+ reabsorption is coupled to K+ secretion in the cortical collecting duct, these drugs can lead to excessive K+ secretion and hypokalemia ([K+] in extracellular fluid is too low). The same is true of loop diuretics (e.g., furosemide). Thiazide and loop diuretics may be combined with potassium-sparing diuretics (e.g., spironolactone) to counteract this possibility. The other actions are also appropriate for this patient but are not as urgent. Focus: Prioritization.
A patient is prescribed meloxicam for rheumatoid arthritis. This drug has a long half-life of 51 hours. Which prescription would the nurse be sure to clarify with the health care provider before giving the medication?
- Meloxicam 7.5 to 15 mg/day
- Meloxicam 15 mg/day before breakfast
- Meloxicam 7.5 mg every 4 hours as needed for pain
- Meloxicam 7.5 mg/day as needed
Ans: 3
A drug’s plasma half-life depends on how quickly the drug is eliminated from the plasma. The half-life of a given medication is how long it takes for the body to get rid of half of the dose. If a drug with a long half-life is given too often or at short intervals, its level can become so high that it is toxic. Focus: Prioritization.
The RN is a team leader working with an LPN/LVN and two unlicensed assistive personnel (UAP) to provide care for eight medical patients. Which action would be appropriate for the RN take with regard to nursing care provided by the LPN/LVN?
- Delegate the performance of an abdominal dressing change to the LPN/LVN.
- Supervise and document the patient assessments completed by the LPN/LVN.
- Assign the LPN/LVN the administration of insulin to a patient with type 1 diabetes.
- Delegate checking and recording vital signs on all eight patients to the LPN/LVN.
Ans: 3
LPN/LVNs are licensed and therefore responsible for their own practice. Their scope of practice includes administration of medications. The RN team leader is responsible for supervision as well as making assignments for LPN/LVNs (team leaders also make assignments for other RNs on the team). Delegation of checking and recording vital signs is appropriate for the UAPs. The LPN/LVN could perform the dressing change, but the RN would assign, not delegate, the task. Focus: Assignment.
A 14-year-old child was recently diagnosed with type 1 diabetes. The patient is prescribed 10 units of regular insulin and 15 units of NPH insulin each morning. How should the nurse instruct this patient to give herself the prescribed doses of insulin?
- “First draw up and administer the NPH insulin. Wait at least 15 minutes; then draw up and administer the regular insulin.”
- “First draw up and administer the regular insulin; then draw up and administer the NPH insulin.”
- “First draw up the NPH insulin; then draw up the regular insulin in the same syringe.”
- “First draw up the regular insulin; then draw up the NPH insulin in the same syringe.”
Ans: 4
When mixing two different type of insulin in the same syringe, inject both bottles with the amount of air equal to the dose of that insulin. Then draw up the short-acting insulin first. Regular insulin is short acting. NPH insulin is an intermediate-acting insulin. Take care not to inject any regular insulin into the NPH bottle. Focus: Prioritization.
A patient with type 2 diabetes has a prescription for a change in oral antidiabetic agents from glyburide to acarbose. The patient asks the nurse why there is no need to be worried about the new drug causing hypoglycemia. What is the nurse’s best answer?
- “Because your pancreatic function is improving, it does not need as much stimulation, so acarbose is not as powerful as glyburide.”
- “Glyburide stimulates your pancreas to secrete insulin, increasing your risk for hypoglycemia. Acarbose does not stimulate insulin secretion; rather, it reduces your intestinal uptake of sugar.”
- “Acarbose increases the cells’ uptake of glucose without the need for insulin, so you cannot become hypoglycemic even if you miss a meal on this medication.”
- “Glyburide is actually an oral form of insulin, and too much could make your blood sugar drop quickly. Acarbose reduces blood sugar by suppressing pancreatic release of glucagon.”
Ans: 2 Glyburide is a sulfonylurea antidiabetic drug. Its action is to lower blood glucose levels by triggering the beta cells of the pancreas to release the small amount of preformed insulin present in the beta cells. Acarbose is an alpha-glucosidase inhibiting drug. Its action is to slow the digestion of dietary starches and other carbohydrates by inhibiting an enzyme that breaks them down into glucose. The result of this action is that blood glucose does not rise as far or as fast after a meal. Drugs from this class do not cause hypoglycemia when taken as the only therapy for diabetes. Focus: Prioritization.
An adult patient with type 2 diabetes is prescribed miglitol 25 mg three times a day with meals. What specific priority instruction about this drug does the RN provide the LPN/LVN assigned to care for this patient?
- “Make certain the patient’s meal is actually on the unit before administering the drug and give the drug with the first bite of the meal.”
- “Check the patient’s blood glucose level to determine whether the drug therapy is having an effect on the diabetes.”
- “Check the patient’s daily urine output and current lab work, especially the blood urea nitrogen (BUN) and serum creatinine levels, because kidney problems increase the effects of the drug.”
- “Make sure that the patient is able to eat and will do so within 30 minutes of taking the drug.”
Ans: 1
Miglitol is an alpha-glucosidase inhibiting drug. Make certain the patient’s meal is actually on the unit before giving the drug. Give the drug with the first bite of the meal. The action of the drug is quick and brief. If the drug is taken too long before the meal is eaten, it will not prevent the carbohydrates from being absorbed, and the patient’s blood glucose level will rise. The other teaching is also appropriate for diabetics but not specific to the effectiveness of miglitol. Focus: Prioritization.
An older adult patient with type 1 diabetes is legally blind and is prescribed daily morning doses of regular and NPH insulin. The patient’s daughter provides in-home care and will be preparing insulin syringes on a weekly basis. What does the nurse teach the patient’s daughter about storing the prefilled insulin syringes?
- “Keep the syringes stored flat and do not attach the needles until you are ready to use a syringe.”
- “Keep the syringes in the upright position with the needle pointing toward the ceiling.”
- “Keep them in the upright position with the needle pointing toward the floor.”
- “Storage position is unimportant as long as the syringes are kept in the refrigerator.”
Ans: 2
Prefilled insulin syringes, cartridges, and pens should be stored upright rather than lying flat. The needle must point upward. Focus: Prioritization.
A female patient with type 2 diabetes who is breast-feeding her newborn infant has a prescription for glipizide. What is the nurse’s best action?
- Administer the drug as ordered with meals.
- Hold the drug and clarify the order with the health care provider.
- Assign the LVN/LPN to administer the drug before breakfast.
- Instruct the unlicensed assistive personnel to check the patient’s fingerstick glucose; then give the drug.
Ans: 2
Glipizide is a second-generation sulfonylurea antidiabetic drug. These drugs are contraindicated for breast-feeding mothers because they enter the milk and increase the infant’s risk for hypoglycemia. Focus: Prioritization.
A patient is to receive metoprolol tartrate 5 mg IV to control high blood pressure. IV metoprolol tartrate is administered over 2 minutes. Based on the label for the medication, the nurse will administer _______________ mL/min.
Ans: 2.5 mg/min
5 mg in 5 mL = 5 mL / 2 min = 2.5 mL/min. Focus: Prioritization.INSERT PIC
Which of the following should the nurse be sure to assess before and after giving amlodipine to treat high blood pressure? Select all that apply.
- Swelling in ankles or feet 2. Heart rate
- Oral temperature
- Blood pressure
- Lung sounds
- Weight
- Respiratory rate
Ans: 1, 2, 4, 5, 6
Amlodipine is a calcium channel blocker with side effects that include peripheral and pulmonary edema, weight gain, decreased heart rate (bradycardia), and decreased blood pressure (hypotension). The nurse would be sure to get a baseline for each of these parameters and then be sure to assess for each regularly after administering the drug. Although respirations and body temperature are parts of vital sign assessment, they are not as high a priority because they are not usually affected by antihypertensive drugs. Focus: Prioritization.
A patient diagnosed with hypertension has received the first dose of lisinopril. Which interventions will the RN delegate to the unlicensed assistive personnel (UAP)? Select all that apply.
- Restrict the patient to bed rest for at least 12 hours.
- Recheck the patient’s vital signs every 4 to 8 hours.
- Ensure that the patient’s call light is within easy reach.
- Keep the patient’s bed in a supine position with all side rails up.
- Remind the patient to rise slowly from the bed and sit before standing.
- Assist the patient to get out of bed and use the bathroom.
- Assess the patient for signs of dizziness.
Ans: 2, 3, 5, 6
After the first dose of most antihypertensive drugs, dizziness is a common side effect. The patient should call for help when getting out of bed, and the call light should be within easy reach. The patient should rise slowly, sitting on the side of the bed before standing, and then can be assisted to the bathroom. The UAP’s scope of practice includes these actions. Patients are not restricted to bed rest or kept in a supine (flat) position, and side rails are not all kept up for safety of the patient. Assessment is not within the scope of practice for a UAP. However, the RN could instruct the UAP to ask the patient about dizziness before and during ambulation and then report any dizziness immediately to the RN. Focus: Delegation; Test Taking Tip: The nurse must be aware of the scope of practice for a UAP to understand which patient care tasks may be delegated. Remember that the nurse may not delegate tasks such as assessment, teaching, evaluating, or administering drugs to a UAP.
An older patient with chronic obstructive pulmonary disease (COPD) is to be discharged with prescriptions for albuterol, a short-acting beta agonist (SABA), and salmeterol, a long-acting beta agonist (LABA) bronchodilator. Which statement by the patient indicates to the nurse that the patient requires additional teaching?
- “I will insert my inhaler into the spacer and shake the whole unit three or four times before taking my dose of the drug.”
- “I will use my salmeterol whenever I become suddenly short of breath.”
- “I will wait at least 1 minute between the first and second puff of my inhaler.”
- “I will check my pulse before and after using my bronchodilator inhaler.”
Ans: 2
Salmeterol is a LABA and is used to prevent episodes of shortness of breath. When a patient becomes suddenly short of breath, the drug of choice would be a SABA such as albuterol. Statements 1, 3, and 4 all demonstrate correct understanding of how to use an aerosol inhaler. An older adult may be more sensitive to cardiac effects of these drugs and should check the heart rate before and after each dose. Focus: Prioritization; Test Taking Tip: The nurse must know the differences between SABA and LABA drugs, including how they work and why they are prescribed, to be able to assess the patient’s understanding of these drugs and determine if additional teaching is required.
Which patient care action could the nurse delegate to unlicensed assistive personnel (UAP) after administering an inhaled anti-inflammatory drug to a patient with chronic obstructive pulmonary disease (COPD)?
- Assess the patient’s mouth for white-colored patches.
- Teach the patient how to clean the inhaler and spacer.
- Assist the patient to rinse the mouth with water or mouthwash.
- Auscultate the patient’s lungs for any changes in breath sounds.
Ans: 3
Side effects of inhaled anti-inflammatory drugs include leaving a bad taste in the mouth after use and increased risk for oral candidiasis (thrush). Rinsing with water or mouthwash helps remove the drug from the mouth and reduce the bad taste and oral infection risk. 1, 2, and 4 are all actions that are within the scope of practice for the RN. Assisting the patient to rinse the mouth after administration of these drugs is within the scope of practice for a UAP. Focus: Delegation.
A patient with familial hypercholesterolemia is prescribed atorvastatin 10 mg once a day. Which finding will the nurse immediately report to the health care provider?
- Stomach upset
- Constipation
- Bloating
- Muscle soreness
Ans: 4
Patients who are prescribed statin drugs such as atorvastatin can develop the adverse effect of rhabdomyolysis. Signs and symptoms include general muscle soreness, muscle pain, weakness, vomiting, stomach pain, and brown urine. When a patient develops these signs and symptoms, the drug needs to be discontinued and another type of antilipidemic drug prescribed. Upset stomach and constipation are common side effect of statin drugs but are not adverse effects. Bloating is a more common side effect of the bile acid sequestrant type of antilipidemic drug. Focus: Prioritization.
What key instruction must the nurse give to the unlicensed assistive personnel (UAP) who is assisting with morning care for an older patient prescribed apixaban, 2.5 mg orally twice a day, for chronic atrial fibrillation?
- “Be sure to tell me if you notice any bleeding from the gums when the patient brushes his or her teeth.”
- “Instruct the patient to avoid using aspirin-containing drugs or nonsteroidal anti-inflammatory drugs.”
- “Teach the patient to expect some bruising to occur because this is a side effect of the drug.”
- “Remind the patient that each morning a laboratory technician will stop by early to draw clotting studies.”
Ans: 1
Apixaban is a direct thrombin inhibitor. Bleeding from the gums is a side effect of these drugs. The nurse should be notified of any bleeding so that she or he can assess this effect. Instructing and teaching are not within the scope of practice for a UAP, but the UAP can remind patients about what the RN has taught. Apixaban does not require laboratory monitoring. Focus: Supervision.