Chapter 2- Nucleic Acids Flashcards
What are the 3 components of a DNA nucleotide?
Pentose sugar (deoxyribose), phosphate group, nitrogen-containing base
How are the components of a DNA nucleotide formed?
Through condensation reactions
What bonds join the nucleotides together?
Phosphodiester bonds
Structure of RNA
-single polypeptide chain
-short
-ribose is the pentose sugar
Bases are adenine, guanine, cytosine, uracil
Structure of DNA
-pentose sugar = deoxyribose
-2 strands in double helix structure
-extremely long
-bases - adenine, guanine, cytosine, thymine
-H bonds between bases
-complementary base pairing = A + T, C+G
How does the structure of DNA relate to its function?
-stable structure = passes through generations without change (rarely mutates)
-H bonds can separate during DNA replication
-extremely large - stores generic info
-bases pairs are within mbackbone - genetic info protected
-base pairing means DNA can replicate
Process of DNA replication (semi-conservative replication)
- DNA helicaxe breaks H bonds between base pairs -> double helix becomes 2 separate strands
- One strand becomes a template
- Free nucleotides bind via complementary base pairing
- Nucleotides are joined together by condensation reactions using DNA polymerase, creating a new polynucleotide strand -> each new DNA strand has 1 original strand + 1 new strand - ‘semi-conservative replication’
What are the 3 components of ATP?
Adenine, pentose sugar (ribose), 3 phosphate groups
Adenosine triphosphate + water -> ? + ?
Adenosine diphosphate + Inorganic phosphate
What type of reaction is: adenosine triphosphate + water -> adenosine diphosphate + Inorganic phosphate? And is it reversible?
Hydrolysis reaction catalysed by ATP hydrolase
Yes it is reversible (other way = condensation reaction catalysed by ATP synthase)
What are the roles of ATP?
-Immediate energy source -> release less than glucose + cells can’t store large quantities of ATP
-ATP energy is released in smaller, manageable quantities
-Hydrolysis of ATP -> ADP = single reaction -> immediate energy
How is ATP used in energy-requiring processes?
-Metabolic processes
-Movement e..g muscle contraction
-Active transport = energy to change shape of carrier proteins
-Secretion
-Activation of molecules -> inorganic phosphate used to phosphorylate other compounds (makes them > reactive)
How is water a polar molecule?
H has slight + charge
O has slight - charge
Features of water
-High SHC - buffer against temp. Variations
-Latent heat of vaporisation - H bonds take lot of energy to evaporate -> effective means of cooling
-cohesion - H bonds have large cohesive forces -> pulled in tube
-surface tension - water pulled back when meeting air - surface acts like a skin
Importance of water in organisms?
-Metabolism - used in reactions in aqueous mediums
-Solvent - dissolves other substances e.g. urea
-Evaporation - cools organisms -> temp control
-X easily compressed - provides support
-Transparent - so aquatic plants can photosynthesise