Chapter 2: CARBOHYDRATES Flashcards
1) Monosaccharides (Hexoses)
- GLUCOSE (DECTROSE)
- FRUCTOSE (LEVULOSE, FRUIT SUGAR)
- GALACTOSE
2) Disaccharides
• Lactose (milk sugar)
= GLUCOSE + GALACTOSE
• Sucrose (Table sugar)
= GLUCOSE + FRUCTOSE
• MAltose
= GLUCOSE + GLUCOSE
3)
• DECREASES blood sugar
• INCREASED blood sugar
- INSULIN
* GLUCAGON, CORTISOL, GROWTH HORMONE, EPINEPHRINE, THYROID HORMONES
4) SPECIMEN COLLECTION and CONSIDERATION
A) Standard clinical specimen is FASTING
B) VENOUS BLOOD HAS LOWER GLUCOSE levels compared to ARTERIAL BLOOD
C) WB gives approx. 10- 15% LOWER glucose levels than serum or plasma
D) At ROOM-TEMPERATURE, glucose DECREASES at a rate of ~~~>7 mg/dL/hr
E) At 4*C glucose DECREASES by approx.2 mg/dL/hr
F) 2 mg of NaF/ mL of WB acts as preservative with another anticoagulant (i.e. k oxalate); PREVENTS GLYCOLYSIS for 48-72 hrs
G) If NaF is Used alone as an anticoagulant, 3-5x GREATER Concentration
H) FLUORIDE binds MAGNESIUM, which causes inhibition of the enzyme ENOLASE
I) CSF glucose concentration is approx. 60-70% that of plasma concentration
J) Blood glucose should be obtained 1-2 hours before the spinal tap
K) 10% contamination with 5% dextrose will INCREASE glucose by 500mg/dL or more