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Pharmaceuticals > Chapter 2 Antidiabetic Agents > Flashcards

Chapter 2 Antidiabetic Agents Flashcards

1
Q

Biguanides

A

Lower basal and postprandial plasma glucose, type 2 diabetes. Decrease hepatic glucose and intestinal absorption. AMPK activation (adenosine monophosphate-activated protein kinase.

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2
Q

Metformin class

A

Biguanides

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3
Q

Metformin brands

A

Fortamet, glucophage, glumetza, riomet

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4
Q

Di-peptidyl peptidase4 inhibitor generic, and use

A

Sitagliptin, type 2 diabetes

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5
Q

Brand name sitagliptin

A

Januvia

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6
Q

Di-peptidyl peptidase4 inhibitor Action

A

Inhibit inactive GLP-1 to active; increases secretion of insulin from pancreas

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7
Q

Insulin releases from where

A

Beta cells of pancreas

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8
Q

Insulin action

A

Lowers blood glucose by causing cells to take up sugar and inhibiting liver glucose production

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9
Q

Insulin glulisine brands

A

Apidra, apidra solistar (rapid acting)

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10
Q

Insulin lispro brands

A

Humalog, humalog kwikpen (rapid acting)

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11
Q

Insulin NPH brands

A

Humalin N, Novolin N

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12
Q

Insulin regular

A

Humalin R, Novolin R

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13
Q

NPH/insulin mix

A

Humulin (Novolin) 70/30, 50/50,75/25

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14
Q

insulin glargine brands

A

Lantau, lantus Solostar

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15
Q

Insulin Detemir

A

Levemir, levemir flexpen

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16
Q

Insulin Aspart brands

A

Novolog, Novolog FlexPen

17
Q

Novolog Mix 70/30

A

70% intermediate acting insulin aspart, 30% quick insulin aspart

18
Q

Sulfonylureas class

A

Type 2 diabetes, lowers blood glucose by increasing beta cell insulin, preg categ c

19
Q

Glimeparide brand

A

Amaryl

20
Q

Glipizide brand

A

Glucotrol

21
Q

Glyburide brands

A

Diabeta, micronase, Glynase PresTab

22
Q

Thiazolidinediones action

A

Decrease insulin resistance in fat, skeletal and liver tissue

23
Q

Pioglitazone brand

A

Actos

Pharmaceuticals (3 decks)

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