Chapter 2 Flashcards
Anterior pituitary
Connected to hypothalamus - network of capillaries.
Capable of producing, storing and releasing hormones.
True endocrine gland, secreting its own hormones
Releasing FSH, LH, ACTH, TSH, prolactin and the growth hormone.
Posterior lobe
Releasing hormones produced by the hypothalamus - through its nerve fibres.
Exocrine gland (have DUCTS!)
Secretion onto surface or onto the body cavities, sweat glands, mucous glands and salivary glands
Endocrine glands (DUCTLESS!)
Secretion of hormones into extracellular fluid surrounding the cells that make up the gland, pineal gland, hypothalamus, pancreas and adrenal glands
Hormone?
Paracrine?
Secretion of an endocrine gland - transported via blood and affect particular target cells and organs.
Secreted by all cells - also diffuses and affects other cells.
Protein/amine
Unable to diffuse through cell membrane, attaches to a receptor on the membrane
There is a release of a secondary messenger which activates enzymes
They can alter gene expression/cell metabolism
Steroid
Diffuses through extra cellular fluid into cell membrane, binds to a receptor inside cell
This therefore activates the hormone-receptor complex to alter gene expression/cell metabolism
Relation between hypothalamus and pituitary gland
- Releases inhibiting or stimulating factors, e.g. Low temperature promoting TSH release
- Produces hormones that are sent to the pituitary
Hormone clearance
Required effect is produced, therefore must be turned off
They are then excreted in the bile/urine
Enzyme amplification
Activation of thousand enzyme molecules by one…