Chapter 2 Flashcards
Which type of inflammation is most associated with the presence of macrophages?
A. Acute inflammation
B. Chronic Inflammation
B.Chronic Inflammation
Which type of inflammation is most likely to result in tissue injury and scarring (fibrosis)?
A. Acute inflammation
B. Chronic inflammation
B. Chronic inflammation
Which of the following is a multi C protein cytoplasmic complex that recognizes products of dead cells and stimulates an acute inflammatory response? A. inflammasome B. cytosome C. lymphasome D. toll-like receptor
A. inflammasome
As"stasis"develops"at"the"site"of"an"acute"inflammatory"reaction,"\_\_\_\_\_\_\_\_\_"initiate"margination"and" rolling? A. Erythrocytes B. myocardial stem cells C. dendritic cells D. leukocytes
D. leukocytes
Inflammation"increases"vascular"permeability,"which"allows"proteinCrich"fluid"into"the"extravascular" tissues."The"resulting"proteinCrich"fluid"accumulation"is"termed"\_\_\_\_\_\_\_\_\_\_."? A. transudate B. reticulocytes C. exudate D. extracellular matrix
A. transudate
Which”type”of”inflammation”is”most”associated”with”the”presence”of”monocytes?
A. acute inflammation
B. chronic inflammation
B. chronic inflammation
The”resolution”stage”of”an”inflammatory”reaction”involves”enzymatic”degradation”of”the”various” chemical”mediators”of”the”reaction”and”normalization”of”vascular”permeability?
T or F
True
Which"morphological"pattern"of"inflammation"is"associated"with"acne"vulgaris? A. Serous B. fibrinous C. purulent D. ulcerative
A. Serous
Focal collections of pus are called? A. comedones B. cysts C. collectins D. abscesses
D. abscesses
TNF, IL-1, and IL-6 are all considered to be? A. kinins B. reactive oxygen species C. inflammasomes D. cytokines
D. cytokines
Activation"of"which"system"generates"a"poreClike"membrane"attack"complex"(MAC)? A. complement system B. kinin system C. neuropeptide system D. cystic system
A. complement system
The"kinin"system"leads"to"the"formation"of"\_\_\_\_\_\_\_\_\_,"which"increases"vascular"permeability? A. cyclokinin B. cyclooxygenase C. FOXP2 D. bradykinin
D. bradykinin
Pyrogens"stimulate"\_\_\_\_\_\_\_\_"synthesis,"which"promote"the"production"of"neurotransmitters"that"reset" the"temperature"set"point? A. Fibrosis B. prostaglandin C. extracellular matrix D. leukocyte
B. prostaglandin
A"white"blood"cell"count"of"16,000"cells"per"microliter"is"considered"to"be"\_\_\_\_\_\_\_\_? A. leukocytosis B. normal C. a leukemoid reaction D. leukopenia
D. leukopenia
Once”the”inflammatory”reaction”has”resolved,”the”body”initiates”the”process”of”healing?
T or F
False
The"normal"size"of"a"cell"population"of"cells"is"determined"by"a"balance"between"proliferating"cells," newly"differentiated"cells,"and"\_\_\_\_\_\_\_\_? A. margination B. apoptosis C. leukocytes D. necrosis
B. apoptosis
Cells"that"are"capable"of"proliferating"in"response"to"injury""or"loss"of"tissue"mass"are"components"of" \_\_\_\_\_\_\_\_\_\_"tissue? A. labile B. stable C. cytosolic D. permanently differentiated
B. stable
A"\_\_\_\_\_\_\_\_\_\_\_"is"an"example"of"a"labile"cell? A. hematopoietic cells B. hepatocyte C. neuron D. cardiac myocyte
A. hematopoietic cells
Hematopoietic”stem”cells”may”be”found”in”the”bone”marrow”as”well”as”the”peripheral”blood?
T or F
True
Which”types”of”stem”cells”are”the”least”differentiated?
A. embryonic stem cell
B. adult stem cell
A. embryonic stem cell
Which"2"of"the"following"are"commonly"involved"in"response"to"increased"growth"factors? A. entry into the cell cycle B. cellular quiescence C. parenchymal necrosis D. prevention of apoptosis
D. prevention of apoptosis
Which"component"of"the"extracellular"matrix"allows"for"tissue"recoil,"following"physical"deformation? A. hyaluronic acid B. proteoglycans C. elastin D. fibrin
C. elastin
Which"fibrous"structural"protein"of"the"extracellular"matrix"provides"structural"integrity"to"large"vessel" walls"and"ligaments? A. collagen B. elastin C. hyaluronan D. fibronectin
A. collagen
The"liver"is"able"to"regenerate"as"much"as"\_\_\_\_\_\_\_\_\_\_"of"surgically"removed"hepatocytes? A. 5% B. 20% C. 60% D. 95%
C. 60%
Extensive”regeneration”can”occur”only”if”the”residual”connective”tissue”framework”is”structurally”intact?
T or F
True
Granulation”tissue”is”_______“vascularized?
A. highly
B. poorly
A. highly
The"major"source"of"growth"factors"that"stimulate"and"activate"fibroblasts"are"derived"from"\_\_\_\_\_\_\_\_\_? A. endothelial cells B. monocytes C. granulocytes D. macrophages
D. macrophages
Extracellular"matrix"is"degraded"by"matrix"metalloproteinases,"which"are"dependent"on"\_\_\_\_\_\_\_\_\_"for" their"activity? A. zinc ions B. iron ions C. reactive oxygen species D. hexanes
A. zinc ions
As”scars”mature,”the”number”of”fibroblasts”and”new”vessls”__________?
A. increase
B. decrease
A. increase
A"surgical"incision"that"was"sutured"is"expected"to"reach"peak"neovascularization"by"day"\_\_\_\_\_\_\_\_\_? A. 1 B. 5 C. 10 D. 30
D. 30
A"wound"is"likely"to"regain"approximately"\_\_\_\_\_"of"the"original"tissue"strength"within"3"months"of" healing? A. 10% B. 50% C. 75% D. 90%
C. 75%