Chapter 2

Question 1

Which type of inflammation is most associated with the presence of macrophages?
A. Acute inflammation
B. Chronic Inflammation

Answer 1

B.Chronic Inflammation

Question 2

Which type of inflammation is most likely to result in tissue injury and scarring (fibrosis)?
A. Acute inflammation
B. Chronic inflammation

Answer 2

B. Chronic inflammation

Question 3

Which of the following is a multi C protein cytoplasmic complex that recognizes products of dead cells and stimulates an acute inflammatory response?
A. inflammasome
B. cytosome
C. lymphasome
D. toll-like receptor

Answer 3

A. inflammasome

Question 4

As"stasis"develops"at"the"site"of"an"acute"inflammatory"reaction,"\_\_\_\_\_\_\_\_\_"initiate"margination"and" rolling?
A. Erythrocytes
B. myocardial stem cells
C. dendritic cells
D. leukocytes

Answer 4

D. leukocytes

Question 5

Inflammation"increases"vascular"permeability,"which"allows"proteinCrich"fluid"into"the"extravascular" tissues."The"resulting"proteinCrich"fluid"accumulation"is"termed"\_\_\_\_\_\_\_\_\_\_."?
A. transudate
B. reticulocytes
C. exudate
D. extracellular matrix

Answer 5

A. transudate

Question 6

Which”type”of”inflammation”is”most”associated”with”the”presence”of”monocytes?
A. acute inflammation
B. chronic inflammation

Answer 6

B. chronic inflammation

Question 7

The”resolution”stage”of”an”inflammatory”reaction”involves”enzymatic”degradation”of”the”various” chemical”mediators”of”the”reaction”and”normalization”of”vascular”permeability?
T or F

Answer 7

True

Question 8

Which"morphological"pattern"of"inflammation"is"associated"with"acne"vulgaris?
A. Serous
B. fibrinous
C. purulent
D. ulcerative

Answer 8

A. Serous

Question 9

Focal collections of pus are called?
A. comedones
B. cysts
C. collectins
D. abscesses

Answer 9

D. abscesses

Question 10

TNF, IL-1, and IL-6 are all considered to be?
A. kinins
B. reactive oxygen species
C. inflammasomes
D. cytokines

Answer 10

D. cytokines

Question 11

Activation"of"which"system"generates"a"poreClike"membrane"attack"complex"(MAC)?
A. complement system
B. kinin system
C. neuropeptide system
D. cystic system

Answer 11

A. complement system

Question 12

The"kinin"system"leads"to"the"formation"of"\_\_\_\_\_\_\_\_\_,"which"increases"vascular"permeability?
A. cyclokinin
B. cyclooxygenase
C. FOXP2
D. bradykinin

Answer 12

D. bradykinin

Question 13

Pyrogens"stimulate"\_\_\_\_\_\_\_\_"synthesis,"which"promote"the"production"of"neurotransmitters"that"reset" the"temperature"set"point?
A. Fibrosis
B. prostaglandin
C. extracellular matrix
D. leukocyte

Answer 13

B. prostaglandin

Question 14

A"white"blood"cell"count"of"16,000"cells"per"microliter"is"considered"to"be"\_\_\_\_\_\_\_\_?
A. leukocytosis
B. normal
C. a leukemoid reaction
D. leukopenia

Answer 14

D. leukopenia

Question 15

Once”the”inflammatory”reaction”has”resolved,”the”body”initiates”the”process”of”healing?
T or F

Answer 15

False

Question 16

The"normal"size"of"a"cell"population"of"cells"is"determined"by"a"balance"between"proliferating"cells," newly"differentiated"cells,"and"\_\_\_\_\_\_\_\_?
A. margination
B. apoptosis
C. leukocytes
D. necrosis

Answer 16

B. apoptosis

Question 17

Cells"that"are"capable"of"proliferating"in"response"to"injury""or"loss"of"tissue"mass"are"components"of" \_\_\_\_\_\_\_\_\_\_"tissue?
A. labile
B. stable
C. cytosolic
D. permanently differentiated

Answer 17

B. stable

Question 18

A"\_\_\_\_\_\_\_\_\_\_\_"is"an"example"of"a"labile"cell?
A. hematopoietic cells
B. hepatocyte
C. neuron
D. cardiac myocyte

Answer 18

A. hematopoietic cells

Question 19

Hematopoietic”stem”cells”may”be”found”in”the”bone”marrow”as”well”as”the”peripheral”blood?
T or F

Answer 19

True

Question 20

Which”types”of”stem”cells”are”the”least”differentiated?
A. embryonic stem cell
B. adult stem cell

Answer 20

A. embryonic stem cell

Question 21

Which"2"of"the"following"are"commonly"involved"in"response"to"increased"growth"factors?
A. entry into the cell cycle
B. cellular quiescence
C. parenchymal necrosis
D. prevention of apoptosis

Answer 21

D. prevention of apoptosis

Question 22

Which"component"of"the"extracellular"matrix"allows"for"tissue"recoil,"following"physical"deformation?
A. hyaluronic acid
B. proteoglycans
C. elastin
D. fibrin

Answer 22

C. elastin

Question 23

Which"fibrous"structural"protein"of"the"extracellular"matrix"provides"structural"integrity"to"large"vessel" walls"and"ligaments?
A. collagen
B. elastin
C. hyaluronan
D. fibronectin

Answer 23

A. collagen

Question 24

The"liver"is"able"to"regenerate"as"much"as"\_\_\_\_\_\_\_\_\_\_"of"surgically"removed"hepatocytes?
A. 5%
B. 20%
C. 60%
D. 95%

Answer 24

C. 60%

Question 25

Extensive”regeneration”can”occur”only”if”the”residual”connective”tissue”framework”is”structurally”intact?
T or F

Answer 25

True

Question 26

Granulation”tissue”is”_______“vascularized?
A. highly
B. poorly

Answer 26

A. highly

Question 27

The"major"source"of"growth"factors"that"stimulate"and"activate"fibroblasts"are"derived"from"\_\_\_\_\_\_\_\_\_?
A. endothelial cells
B. monocytes
C. granulocytes
D. macrophages

Answer 27

D. macrophages

Question 28

Extracellular"matrix"is"degraded"by"matrix"metalloproteinases,"which"are"dependent"on"\_\_\_\_\_\_\_\_\_"for" their"activity?
A. zinc ions
B. iron ions
C. reactive oxygen species
D. hexanes

Answer 28

A. zinc ions

Question 29

As”scars”mature,”the”number”of”fibroblasts”and”new”vessls”__________?
A. increase
B. decrease

Answer 29

A. increase

Question 30

A"surgical"incision"that"was"sutured"is"expected"to"reach"peak"neovascularization"by"day"\_\_\_\_\_\_\_\_\_?
A. 1
B. 5
C. 10
D. 30

Answer 30

D. 30

Question 31

A"wound"is"likely"to"regain"approximately"\_\_\_\_\_"of"the"original"tissue"strength"within"3"months"of" healing?
A. 10%
B. 50%
C. 75%
D. 90%

Answer 31

C. 75%