Chapter 2 Flashcards

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1
Q

2 steps prior to cancer appearance in animals

A

initiation
promotion

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2
Q

_______ follows cancer appearance and also includes invasion and metastasis

A

progression

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3
Q

molecular studies aim to identify:

A

discrete mutational events

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4
Q

example of external agents as initiators/promoters

A

soot causing scrotal cancer in young chimney sweeps

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5
Q

mouse skin painting is an example of:

A

a multistep system - neither agent alone causes cancer

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6
Q

many initiators must be ______ to a reactive metabolite

A
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