Chapter 2 Flashcards

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1
Q

Meiosis

A

Formation of gametes in which the number of chromosomes is reduced

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2
Q

Fertilization

A

Two haploid gametes fuse and restore the number of chromosomes to its original diploid value

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3
Q

What are the five stages of prophase I

A
  • Leptotene
  • Zygotene
  • Pachytene
  • Diplotene
  • Diakinesis
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4
Q

Leptotene

A

Chromosomes condense and become visible

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5
Q

Zygotene

A

Chromosomes continue to condense, homologous chromosomes pair up and begin synapse – a close association

Homologous pairs come together to form a synapse

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6
Q

Bivalent/Tetrad

A

Each homologous pair of chromosomes, 2 chromosomes and 4 sister chromatids

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7
Q

Pachytene

A

Chromosomes become shorter and thicker, and a three-part synaptonemal complex develops between homologous chromosomes

A protein between the two chromosomes form

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8
Q

Crossing Over

A

In which homologous chromosomes exchange genetic information

Intra - chromosomal recombination

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9
Q

Chiasma

A

The location where two chromosomes cross over

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10
Q

Diplotene

A

The centromeres of the two homologous chromosomes move apart

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11
Q

Diakinesis

A

Chromosome condensation continues…the nuclear membrane breaks down

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12
Q

Metaphase I

A

Homologous chromosomes align up on the metaphase plate

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13
Q

Anaphase I

A

Homologous chromosomes move apart – the sister chromatids remain attached

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14
Q

Telophase I

A

The chromosomes arrive at the spindle poles, and the cytoplasm divides – interkinesis

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15
Q

Interkinesis

A

The nuclear membrane reforms around the chromosomes clustered at each pole, the spindle apparatus breaks apart, and the chromosomes relax

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16
Q

Prophase II

A

The events of interkinesis are reversed

17
Q

Metaphase II

A

sister chromatids align on the metaphase plate

18
Q

Anaphase II

A

The sister chromatids separate

19
Q

Telophase II

A

The chromosomes arrive at the spindle poles, a nuclear membrane reforms around the chromosomes and the cytoplasm divides – cytokinesis
chromosome become no longer visible

20
Q

What causes genetic variation?

A
  1. Crossing Over in Prophase I
  2. Random separation of homologous chromosomes in Metaphase I
21
Q

What evidence from yeast relay about crossing over?

A

Crossing over starts from zygotene and ends until the end of Prophase I

22
Q

Intra-chromosomal Recombination

A

The creation of new combinations of alleles on a chromatid

23
Q

Cohesins

A

They control the segregation or the separation of homologous chromosomes during mitosis and meiosis

  • protein rings
24
Q

What holds homologous chromosomes together?

A

Cohesins along the chromosome arm hold homologs together

25
Q

What holds sister chromatids together?

A

Cohesins along the centromere hold sister chromatids along

26
Q

Which protein protect centromere cohesins during Anaphase I?

A

Shugoshin – “guardian spirit” in Japanese…is degraded later on before Anaphase II