Chapter 2 Flashcards

1
Q

What is the cell theory?

A

Cell Theory
- All organisms are composed of one or more cells.
● Prokaryotes - one cell (unicellular- carry out activities necessary for life)
● Eukaryotes - one or more cells (uni or multicellular- the activities of life are divided among numerous types of specialized cells)

  • The cell is the basic structural and functional unit of all living organisms. (cannot separate mitochondria or other individual parts)
  • Cells arise only from the division of preexisting cells (do not occur spontaneously)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What two types of microscopes are used to see cells and the structures within them?

A

Light microscopes use light to illuminate the specimen

Electron microscopes use electrons to illuminate the specimen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How big are cells?

A

Most cells are too small to be seen by the unaided eye—ranging from about 0.5 μm (bacteria) to a few hundred micrometres (plant cells)

Largest known cell called Valonia Ventricosa (algae)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the plasma membrane and what are its main functions?

A

All cells are surrounded by the plasma membrane, a bilayer made of lipids with embedded protein molecules

  • Plasma membrane - bilayer made of lipids w/ embedded protein molecules
  • Plasma membrane consists of phospholipid bilayer - hydrophobic barrier to water-soluble
    substances

● Selected water-soluble substances can penetrate cell membranes through the transport of protein
channels
● Selective transport of ions + water-soluble molecules maintain specialized internal
environments required for cellular life
● Amphipathic - hydrophobic tail, hydrophilic head

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the differences between prokaryotic cells and eukaryotes?

A

Prokaryotic cell (characteristic of domains Bacteria and Archaea)
□ The nucleoid region has no boundary membrane (no nucleus)
□ Many Bacteria and Archaea species contain few if any internal membranes

Eukaryotes (domain, or sub-domain?, Eukarya)
□ Have a membrane-bound compartment called the nucleus
□ Cytoplasm typically contains extensive membrane systems that form organelles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What type of cell is single-cellular but still eukaryotic?

A

Protists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the characteristics of Eukaryotic cells?

A

The eukaryotes include animals, plants, fungi and protists

Eukaryotic cells have a membrane-bound compartment called the nucleus
► ”eu” = “true” or “well”; “karyon” = “kernel” or “nucleus”
► “pro” = “before”

The eukaryotic cytoplasm contains a system of membranous organelles, specialized to carry out functions of energy metabolism and molecular synthesis, storage, and transport

The cytosol participates in energy metabolism and molecular synthesis and functions in support and motility
Photosynthesis occurs in the chloroplasts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the characteristics of prokaryotic cells?

A

Three shapes are common among bacterial prokaryotes: spherical, rodlike, and spiral

Information from DNA has copied into messenger RNA (mRNA) molecules and carried to ribosomes in the cytoplasm, which assemble amino acids into proteins

The plasma membrane is typically surrounded by a more rigid bilayer external cell wall coated with polysaccharides (glycocalyx)- assume they all have a cell wall, it is a slime layer; when it is firmly attached, it is a capsule

The plasma membrane contains molecular systems that metabolize food molecules (or light energy) into the chemical energy of ATP (cellular respiration occurs in prokaryotes)

Many bacteria and archaeans move using long flagella—the bacterial flagellum rotates in a socket and pushes the cell through a liquid medium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How do the plasma membrane and cell wall relate?

A

The eukaryotic plasma membrane is responsible for many functions involving multiple types of integral membrane proteins:
► Channel proteins transport substances in and out of cells
► Receptors recognize and bind specific signal molecules in the cellular environment and trigger internal responses
► Immune system proteins label cells as “self”
► Membranes and membrane proteins covered

A supportive cell wall surrounds the plasma membrane of fungal, plant, and many protist cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are Eukaryotic Ribosomes?

A

consist of large and small subunits
□ Designated as “80S” ribosomes (prokaryotic, mitochondrial and chloroplast ribosomes are referred to as “70S”)

Some ribosomes are freely suspended in the cytosol; others are attached to the membrane of the endoplasmic reticulum

Proteins made on free ribosomes may remain in the cytosol, pass into the nucleus, or become parts of mitochondria, chloroplasts, cytoskeleton, or other cytoplasmic structures

Proteins made on ribosomes attached to the endoplasmic reticulum (ER) follow a special path to other organelles in the cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is magnification?

A

The ratio of the object as viewed to its real size (e.g., 1200X, 400:1)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is resolution?

A

The minimum distance that two points in the specimen can be separated and still be seen as two points

Depends primarily on the wavelength of light or electrons used to illuminate the specimen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Why are cells so small?

A

Cell size is limited by the surface area-to-volume ratio

The volume of a cell determines the amount of chemical activity that can take place within the cell.

Surface area determines the number of substances that can be exchanged between a cell and the outside environment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

When a cell gets bigger, does its surface area-to-volume ratio go up or down? Explain

A

● Bigger cell = more capacity to undertake biochem rxns
- Surface area determines the number of substances that can be exchanged b/w cell and outside environment

● Bigger SA = more space to move things in/out
- Doubling diameter of cell = increase SA by 4x = incrase volume by 8x
- Increase size of cell = V + SA don’t increase at same rate = ratio so unproportionate that SA won’t be able to support the biochem means that V can manage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the difference between the word prokaryote and prokaryotic cell?

A
  • Prokaryote - describes a unique group of evolutionarily related organisms
  • Prokaryotic cell - refers to a particular cell architecture
    ● Lacks nucleus & not to single group of organisms
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

In what way is scanning electron microscopy different from transmission electron microscopy?

A

Scanning e- microscopy - a beam of e- scanned across a whole cell or organism
● e- excited on the specimen surface is converted to a 3D appearing image

Transmission e- microscopy - a beam of e- focused on a thin section of specimen in a vacuum
● e- that pass through from the image
● Structures that scatter e- appear dark
● Used primarily to examine structures w/in cells
● Staining + fixing methods used to highlight structures of interest

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is featured in the internal organization of the cell?

A

Central region
Genes
Cytoplasm
Cytoskelton
Cytosol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is the central region?

A

Contains DNA molecules, which store hereditary information (genes)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Genes?

A

segments of DNA that code for individual proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Cytoplasm?

A

Between the plasma membrane and the central region, contains the cytosol and cytoskeleton

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Cytosol?

A

Aqueous solution containing ions, various organic molecules, and organelles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Cytoskeleton?

A

Maintains cell shape and plays key roles in cell division, chromosome segregation, and transportation within the cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What is the nucleus?

A

Separated from the cytoplasm by the nuclear envelope, which consists of two membranes

One membrane is layered just inside the other and separated by a narrow aqueous space (2 phospholipid bilayers)

Nuclear pore complexes embedded in the nuclear envelope regulate the transport of proteins and RNA molecules between the nucleus and cytoplasm (messenger RNA)

A channel through the nuclear pore complex, a nuclear pore, is the path for the assisted exchange of large molecules with the cytoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What is the space inside the nucleus is mostly occupied by?

A

chromatin (a substance that is produced after combining), a combination of DNA and proteins

Chromatin can be more or less condensed at different times, giving chromosomes a different appearance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

In eukaryotes, each DNA molecule is linear, and associates with proteins into chromosomes?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Does a eukaryotic nucleus contain one or more nucleoli, formed around the genes coding for rRNA molecules (transcription) of ribosomes (several different rRNA that go into forming ribosomes)?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

How are ribosomal subunits formed and where do they exit?

A

Ribosomal subunits are formed in nucleoli and exit the nucleus through nuclear pore complexes. In the cytoplasm, they combine with other rRNA molecules and proteins to form ribosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

What are ribosomes are the site of? What occurs?

A

Ribosomes are the site of translation, where mRNA is converted into proteins. Expression of genes is carefully controlled, according with the function of each cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

More protein = more ribosomes = nucleoli will be larger?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

3 most common shapes of prokaryotes?

A

Spherical, rodlike, spiral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Eukayotic cells have an …. system that divides the cell into functional and structural compartments

A

Endomembrane

collection of interrelated internal membranous sacs that divide a cell into
functional and structural compartments

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

What are the compnent of the endomembrane system?

A

The membranes may be connected directly (physically) or indirectly by vesicles, small membrane-bound sacs that transfer substances between parts of the system

ER
Nuclear envelope
Golgi
Lysosomes
Vacuoles
Plasma membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

What is the ER?

A

Endoplasmic reticulum (ER)
→ Extensive interconnected network (reticulum) of membranous channels and
cisternae
→ Each cisterna is formed by a single membrane that surrounds an enclosed space (ER lumen)

ER occurs in two forms: rough ER and smooth ER

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

What is the difference between the rough ER and the Smooth ER

A

Rough ER has many ribosomes attached to its outer surface

Proteins that are made on ribosomes attached to the ER enter the ER lumen or become integrated into the ER membrane

Rough ER contains ribosomes, proteins, lumen, carbohydrates

Proteins are then delivered to other regions of the cell (Golgi complex) using small vesicles that form from the ER

Smooth ER membranes have no ribosomes attached to their surfaces (no porteins being made)

synthesizes lipids that become part of cell membranes, stores Ca2+ ions and cell signaling

In the liver, smooth ER converts drugs, poisons, and toxic by-products into substances that can be tolerated or more easily and removed from the bod

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

What is the golgi complex?

A

The Golgi complex consists of a stack of flattened, membranous sacs (cisternae)

Responsible for final modification, sorting, + distribution of proteins + lipids

Proteins enter cis face through vesicles and modified porteins exit by trans face to plasma membrane (from which they leave out of cell by exocytosis)

Add carbs, lipids + functional groups (can cut but NOT add amino acids)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Exocytosis?

A

A secretory vesicle fuses with the okasma membrance, releasing the vesicle contets to the cell exterior. The vesicle membrane becomes a part of the plasma mebrane

Can be used to deliver plasma membrane proteins to the plasma membrane.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

What is the relationship between the golgi complex and exocytosis?

A

The Golgi complex “sorts” proteins to ensure they are delivered to their final destination. (some proteins are taken back).

Proteins to be secreted from the cell are transported to the plasma membrane in secretory vesicles, which release their contents to the exterior by exocytosis

The membrane of the vesicle fuses with the plasma membrane and becomes part of the plasma membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

Endocyosis?

A

Materials from the cell exterior are enclosed in a segment of plasma membrane that pockets inward and pinches off as an endocytic vesicle

Vesicles also form by the reverse process, endocytosis, which brings molecules into the cell from the exterior

The plasma membrane forms a pocket, which bulges inward and pinches off into the cytoplasm as an endocytic vesicle

Endocytic vesicles carry materials to the Golgi complex or other destinations such as lysosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

What are lysosomes?

A

Lysosomes are small, membrane-bound compartments containing hydrolytic enzymes that digest complex molecules
► Cells recycle the constituents of these molecules

Found in animals + plants (eukaryotes)

Formed by budding from golgi complex

pH in lysosome is acidic (5) < pH of cytosol (7.2)

  • Lysosomes do not digest endocytic vesicles
    ● Secretory vesicles carry materials out
    ● Endocytic vesicles carry materials in

In lysosomal storage diseases, one of the hydrolytic enzymes normally found in the lysosome is absent (cannot break down and recycle things).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Vesicle traffic and the endomembrane system porcess

A
  1. Proteins made by ER
    ribosomes enter ek membranes
    or the space inside ER cisternae.
    Chemical modification of some
    proteins begins. Membrane lipids
    are also made in the ER.
  2. Vesicles bud from
    the ER membrane and
    then transport unfinished
    proteins and lipids to the
    Golgi complex.
  3. Protein and lipid
    modification is completed
    in the Golgi complex, and
    products are sorted into
    vesicles that bud from
    the complex.
  4. Secretory vesicles budding
    from the Golgi membranes
    transport finished products to the
    plasma membrane. The products
    are released by exocytosis. Other
    vesicles remain in storage in
    the cytoplasm.
  5. Lysosomes budding from the
    Golgi membranes contain
    hydrolytic enzymes that digest
    damaged organelles or the
    contents of endocytic vesicles that
    fuse with them. Endocytic vesicles
    form at the plasma membrane
    and move into the cytoplasm.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

What is a nucleoid?

A

Nucleoid - central region of a prokaryotic cell with no boundary membrane separating it from the
cytoplasm (containing cytosol + cytoskeleton), where DNA replication and RNA transcription occur

Genetic material of archaea and bacteria in nucleoid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

Some bacteria and archaeans have internal membranes. How are these internal membranes formed?

A

Endomembrane system - a collection of internal membranes that divide cell into structural +
functional regions

● Include golgi complex, ER, + nuclear envelope
- Internal membranes formed infolding of plasma membrane
● Most often the sites of photosynthetic + respiratory e- transport chains

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

Basic structure of prokaryotic cell

A

Plasma membrane surrounded by cell wall
- Cell wall - provides rigidity to prokaryotic cells
- Cell wall coated w/ glycocalyx - a carbohydrate coat covering the cell surface
● Glycocalyx diffused + loosely associated w/ cells = slime layer
● Glycocalyx gelatinous + more firmly attached to cells = capsule
● Helps prokaryotic cells from physical damage + desiccation
● can enable cell to attach to surfaces s/a other prokaryotic cells (forming a colony),
eukaryotic cells (streptococcus attaching to lung cells), or non-living substrate (rock)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

Where in a eukaryotic cell is DNA found? How is that DNA organized?

A

DNA found in nucleus
- Space inside nucleus mostly occupied by chromatin (combo of DNA + proteins)
- DNA molecule is linear and organized as chromosome
● DNA → histones → nucleosome (made of 8 histones) → chromatin (4 nucleosomes) → chromosome

45
Q

What is the nucleolus and what is its function?

A

Nucleolus (plural - nucleoli) - nuclear sites of rRNA transcription, processing + ribosome assembly
in eukaryotes
- Function
● Info in rRNA genes copied into rRNA molecules, combine w/ proteins to form ribosomal subunits
● Ribosomal subunits leave nucleoli + exit nucleus through nuclear pore complexes to enter cytoplasm = join onto mRNA to form complete ribosome
- Ribosomal subunits made of one large + one small subunit

46
Q

What is the nuclear envelop?

A

In eukaryotes, membrane separating nucleus from cytoplasm

47
Q

Vacuoles?

A

Large vesicles identified as distinct organelles of plant cells

Tonoplast (surrounds central vacuole) contains transport proteins moving substances in/out of central vacuole

Store salts, organic acids, sugars, storage proteins, waste products, pigments

48
Q

Plasma Membrane?

A

Outer limit of cytoplasm responsible for regulation of substances moving in/out of cells

Bilayer made of lipids w/ embedded protein molecules

Nuclear proteins NOT an integral protein in plasma membranes

49
Q

What is the structure and function of a mitochondrion?

A

Mitochondrion (plural - mitochondria) - membrane-bound organelle responsible for synthesis ofmost of ATP in eukaryotic cells (where cellular respiration occurs)

● 2 membranes surrounding mitochondrial matrix (innermost compartment/liquid of
mitochondrion) - outer (covers organelle) & inner (expanded by cristae)
● ATP synthesis in matrix + cristae
● Folds = more SA for cellular respiration
● Inner membrane SA > outer membrane SA

50
Q

What is the mitochondria?

A

Membrane-bound organelles in which cellular respiration occurs

Cellular respiration is the process by which energy-rich food molecules are broken down to water and carbon dioxide by mitochondrial reactions, and energy is converted to ATP

Require oxygen for cellular respiration
→ In animals, breathing provides the oxygen to keep the process going

Two membranes surrounding the inner soluble compartment (the mitochondrial matrix)

The outer mitochondrial membrane covers the organelle; the inner mitochondrial membrane is expanded by folds called cristae

51
Q

Where does ATP-generating reactions occur in?

A

The cristae and matrix

52
Q

What is the structure and function of the cytoskeleton?

A

An interconnected system of protein fibers and tubes that extends throughout the cytoplasm

The cytoskeleton maintains a cell’s characteristic shape and internal organization, and functions in movement

The cytoskeleton of animal cells is comprised of microtubules, intermediate filaments, and microfilaments

53
Q

What are the functions of the microtubules?

A

Assembled from dimers of alpha (+ end) and beta (- end) tubulin proteins
- 25 nm outer diameter (15 nm inner diameter)
- DO NOT hold CELLS in place
- Provide tracks for vesicles by moving along microtubules through push/pull mvmts
(ex. Motor proteins s/a kinesin & diesin), vesicles move between the cell interior and the plasma membrane
- Have polarity (+ and - ends)
- Dynamic = change lengths by addition/removal of tubulin dimers
- Tubulin → microtubules → centrioles (9 triplets of microtub) → centrosome (comprised of two short, barrel-shaped structures- centrioles) → MTOC (microtubule organizing centre - holds organelles in place)
- Organizes microtubule arrays that are involved in various processes
» mitosis, holding organelles in position, and others

54
Q

What are the functions if intermediate filaments?

A

cytoskeletal filament providing mechanical strength + structural support to cells in tissues

Intermediate in size between microtubules and microfilaments (8-12 nm)

Assembled from a large and varied group of intermediate filament proteins

Occur singly, in parallel bundles, and in interlinked networks

Provides structural support in many cells and tissues, and are tissue-specific in their protein composition

Stable, form + stay the way they established

Microfilaments < intermediate filaments < microtubules

55
Q

What are the functions of micofilaments?

A

thin protein fibres assembled from actin subunits

5-7 nm diameter

Polarity (+ and - ends)

Involved in cytoplasmic streaming - intracellular movmentt of cytoplasm

Can transport nutrients, proteins + organelles in plant/animal cells → responsible for amoeboid movment

Structural + locomotor functions (contractile elements in muscle fibres, divide cytoplasm when animal cells divide)

56
Q

What are specilizaed structure of plant cells?

A

· Several structures are found in plant cells but not in animal cells:
► Chloroplasts
► A large central vacuole
► Plant cell walls
Chloroplasts also occur in algal protists, and cell walls in algal protists and fungi

57
Q

What are flagella and Cilia and what are theit functions?

A

Elongated, motile structures that extend from the cell surface

Cilia are shorter than flagella and occur in greater numbers

Movements of a flagellum propel a cell through a watery medium, and cilia move fluids over the cell surface

Cilia and flagella are found in protozoa and algae

Many types of animal cells have flagella—the tail of a sperm cell is a flagellum—as do the
reproductive cells of some plants

Cilia covers the surface of cells lining cavities or tubs in some parts of the body. (cilia on cells lining the ventricles (cavities) of the brain circulate fluid through the brain, and cilia in the oviducts conduct eggs from the ovaries to the uterus.

genes that encode the components of the flagellar apparatus of cells of Bacteria, Archaea, and Eukarya are different in each case.

58
Q

Flagella and Ciliary beating patterns?

A

Flagella beat in
smooth, S-shaped
waves that travel
from base to tip.

Cilia beat in an
oarlike power stroke
(dark orange) followed
by a recovery stroke
(light orange).

59
Q

Plants are a?

A

Photoautotroph (produces its own energy using light)

60
Q

In plant cell, function of plastids?

A

Chloroplasts yellow-green plastids—the sites of photosynthesis in plant cells

Others colorless and store starch (or other molecules), others are brightly colored with pigments such as carotenoids or lycopene

Contain DNA genomes + molecular machinery for gene expression and synthesis of porteins and ribosomes

  • Some of the proteins within plastids are encoded by their genomes; but most are encoded by nuclear genes and are imported into the organelles from the cytosol
61
Q

What is choloplasts in a plant cell?

A

● Surrounded by inner + outer membrane (inside the inner membrane = stroma)
● Inside stroma = thylakoids (flattened, closed sacs) which contain chlorophyll (green pigment
converted into chem energy in photosynthesis)
- Thylakoids stacked = grana
- Thylakoid membrane encloses thylakoid lumen - soluble compartment

  • Thylakoid membranes contain chlorophyll, a green pigment that absorbs light energy that is ultimately converted into chemical energy in photosynthesis
62
Q

In plant cells, what is the function of the vacuole?

A

Vacuoles - large vesicles identified as distinct organelles of plant cells

90% or more of the cell’s volume may be occupied by one or more large central vacuoles

  • Tonoplast (surrounds central vacuole) contains transport proteins moving substances in/out of
    central vacuole
  • Store salts, organic acids, sugars, storage proteins, waste products, pigments
    ● Contain enzymes breaking down biological molecules
    ● Provide chem defences against pathogenic organisms
    ●Supports the cell structure
    ●Pigments produce colors of many flowers and fruits (e.g. red-blue anthocyanin pigments used by flowers)
63
Q

What are the functions of the cell walls?

A
  • Plant cell walls
    ● Support individual cells, support + protect against invading bacteria
    ● Cell walls made of cellulose (long polymers of glucose - most abundant molecule), Aggregate into bundles called microfibrils, Embedded in a network of other polysaccharides
    ● Walls of adjacent cells held together by middle lamela (layer of polysaccharides - pectin)
    ●Contribute to the turgor pressure produced in the central vacuole
64
Q

What role do plasmodesmata serve in the plant cell wall?

A

cell walls perforated by cytosol-filled channels lined by plasma membrane

Primary and secondary cell walls are perforated by plasmodesmata

1000 to 100 000 plasmodesmata in typical plant cell wall

Allow ions + small molecules to move directly from one cell to another through connecting
cytosol w/o having to penetrate plasma membrane or cell walls

Proteins + nucleic acids move through some plasmodesmata using energy dependent
processes

65
Q

What occurs in The Animal Cell Surface?

A

Cell adhesion molecules organize animal cells into tissues and organs

Animal cells have specialized structures that organize cells at three levels:
1. Individual cell adhesion molecules bind cells together
2. Cell junctions seal the spaces between cells and provide direct communication between cells
3. Extracellular matrix (ECM) supports and protects cells and provides mechanical linkages between tissues

66
Q

What do cell adhesion molecules do?

A

Glycoproteins (proteins with carbohydrates, made in the ER) in the plasma membrane that bind to specific molecules on other cells ●

Organize animal cells into tissues and organs

Cancer cells typically lose these adhesions, allowing them to break loose and migrate to new locations (which allow cancer cells to move around the body)

Cell junctions reinforce cell adhesions and provide avenues of communication

67
Q

What are the 3 cell junctions in animal cells?

A

Anchoring, tight and gap

68
Q

Define and describe functions of anchoding junctions.

A

Form buttonlike spots, or belts, that run entirely around cells, “welding” adjacent cells together

Desmosomes- anchoring junctions with intermediate filaments that anchor the junction in underlying cytoplasm

Adheres- anchoring junctions with microfilaments as the anchoring cytoskeletal component

● Wield adjacent cells together
● Most common in tissues subject to stretching, shear
● Have strings poking out
● Ex. heart muscle, skin

69
Q

Define and describe functions of tight junctions.

A

Regions of tight connections between membranes of adjacent cells

Seal spaces between cells in cell layers that cover internal organs, outer surface of the body, or layers that line internal cavities and ducts

Formed by direct fusion of proteins on the outer surfaces of plasma membranes of adjacent

Connection so tight it can keep particles as small as ions from moving b/w cells in layers

Look like stitch work
● Ex. tight junctions b/w stomach, intestine, bladder

70
Q

Define and describe functions of gap junctions.

A

Open direct channels that allow ions and small molecules to pass directly from one cell to another

Hollow protein cylinders embedded in plasma membranes of adjacent cells connects the cytoplasm of one cell with the cytoplasm of the next

Gap junctions communicate between cells within a tissue, such as heart muscle tissue

Occur b/w cells w/in almost all body tissues but not b/w cells of diff tissues
● Ex. heart muscle tissues, smooth muscle tissues forming uterus

71
Q

What is the structure and function of the ECM?

A

Extracellular Matrix (ECM) - molecular system supporting and protecting cells + providing mechanical linkages

Many animal cells are embedded in an ECM that consists of proteins and polysaccharides secreted by the cells themselves

ECM provides protection and support, also affects cell division, adhesion, motility, and embryonic development, and takes part in reactions to wounds and disease

  • Structure + support
  • Forms mass of skin, bones, tendons, highly specialized extracellular structures
  • Glycoproteins main component of ECM
  • Consistency of ECM (from soft/jellylike to hard/elastic) depends on network of proteoglycans that surround collagen fibres
    ● Tendons = almost pure collagen = tough + elastic
  • In cartilage, which contains a high proportion of interlinked glycoproteins, the ECM is relatively soft
  • In bone, the network is impregnated with mineral crystals, producing an ECM that is dense and hard, yet elastic
72
Q

All organisms are composed of more than once cell.

A
  • False (single-cell organisms exist)
    • 1 cell in prokaryotes
      1 or more cells in eukaryotes
73
Q

The cell is the basic structural and functional unit of life.

A

True

74
Q

Cells can spontaneously develop

A

False

75
Q

Why are cells so small?

A

Area-to-volume ratio (volume of cell determines how much chemical reaction, must be proportional)

76
Q

All cells are surrounded by a plasma membrane which is hydrophilic

A

False (hydrophobic- doesn’t like water)

77
Q

The lipid bilayer contains

A

Phospholipid molecules ( hydrophilic tails and hydrophobic heads)

78
Q

The order of components in the phospholipid bilayer

A

Head, tail, tail, head

79
Q

A gene is a segment of DNA that codes for multiple proteins

A

False (a gene codes for a protein)

80
Q

What is not contained in cytosol?

A

Cytoplasm ( cytoplasm contains cytosol and cytoskeleton)

81
Q

Which is not one of the three common shapes among bacterial prokaryotes?

A

Circular

82
Q

Prokaryotes contain:

A

Nucleoid (nucleolus in the nucleus)

83
Q

The plasma membrane is usually surrounded by a cell wall coated with polysaccharides in prokaryotes:

A

True

84
Q

The polysaccharide coating is also known as:

A

Glycocalyx, capsule, slime layer (slime is hard it is like a pill which Is capsule)

85
Q

Cell walls are only found In prokaryotes:

A

False (some eukaryotes have cell walls like plants)

86
Q

Which is not a type of integral; protein in eukaryotic plasma membranes?

A

Nuclear (recognition so your body knows which cells are cells)

87
Q

Chromatin is a combination of DNA and proteins

A

True

88
Q

Ribosomal subunits are formed in the nucleoli prokaryotic cells

A

False (prokaryotic cells do not have nucellus and nucleoli, true for eukaryotes)

89
Q

Eukaryotic ribosomes have one large subunit and two small subunits

A

False (one large unit, one small unit)

90
Q

Which is not part one the endomembrane system:

A

DNA

91
Q

Rough ER does not contain

A

Vacuoles

92
Q

Smooth ER membranes have no ribosomes attached to their surfaces

A

True (in the rough ER no smooth ER)

93
Q

What is a function of the smooth ER?

A

Synthesise lipids (not synthesize proteins because rough ER is where proteins are made because it has ribosomes)

94
Q

Proteins are delivered from the rough ER to the Golgi complex using small vesicles

A

True (rough ER to the Golgi to the vesicles)

95
Q

Proteins from the ER enter the Golgi on the trans face of the complex

A

False (enter on the cis face)

96
Q

What is not a function of the Golgi complex?

A

Add amino acids (ribosomes are on rough ER which add amino acids)

97
Q

Secretory vesicles carry materials to the Golgi complex and lysosomes

A

False (secretory vesicles carry out materials, endocytic bring materials in)

98
Q

Which is not something that lysosomal enzymes digest?

A

Endocytic vesicles (morphs with vesicle)

99
Q

The intramitochondrial membrane is expanded by folds called cristae

A

True

100
Q

Atp-generating reactions occur in the cristae and matrix

A

True (inside mitochondria is called matrix)

101
Q

What is the smallest component of the cytoskeleton?

A

Microfilaments

102
Q

Microtubes are assembled from dimers of A-tubulin and B-tubulin proteins

A

True

103
Q

What do microtubules not do?

A

Hold cells in place (providing tracks for vesicles- kinesin and disoin are molecules that move along the microtubes which provide tracks)

104
Q

What do microtubules not do?

A

Hold cells in place (providing tracks for vesicles- kinesin and disoin are molecules that move along the microtubes which provide tracks)

105
Q

Motor proteins such as myosin push or pull against microtubules to generate filaments

A

False (kinesin and disoin not myosin)

106
Q

What is true about intermediate filaments

A

provides structural support (Microtubules are 25 cm and provide tracks for vesicles.)

107
Q

What isn’t true about microfilaments?

A

they have polarity( different charges on different ends), they have acting subunits, involved in cytoplasmic streaming (all true), microtubules have polarity

108
Q

What is not specialized structure of plant cells?

A

Cytoskeleton (eukaryotic and prokaryotic cells have cytoskeletons)