Chapter 18: Oxidative Phosphorylation Flashcards
How does the citric acid cycle lead into oxidative phosphorylation?
Answer:
Where in the cell does oxidative phosphorylation take place?
Answer:
What factors regulate oxidative phosphorylation?
Oxidative phosphorylation is not regulated by hormones or allosteric regulation.
Is essentially regulated by levels of molecules used in process.
NADH
FADH2
ADP
ATP
O2
The primary regulating factors are the levels of ADP and ATP though.
What does the movement of electrons through the electron transport chain power?
The pumping of protons from the matrix to the inner membrane space.
What are the two electron carriers in oxidative phosphorylation?
Answer:
What are the names of the complexes in the electron transport chain?
Complex I: NADH-Q-oxidoreductase
Complex II: Succinate-Q-reductase
Complex III: Q-cytochrome c oxidoreductase
Complex IV: Cytochrome c oxidase
Why do we need oxygen?
To be reduced at the end of the electron transport chain to water.
What happens if no oxygen is present?
Answer:
How does the electron transport chain lead to the creation of ATP?
Answer:
What is the name of the enzyme that assembles ATP?
ATP synthase
About how many ATP molecules are made per NADH that goes into oxidative phosphorylation?
3 ATP molecules per molecule of NADH
About how many ATP molecules are made per FADH2 that goes into oxidative phosphorylation?
2 ATP molecules per molecule of FADH2
How many molecules of ATP are created per molecule of glucose (assuming that the process goes from glycolysis to citric acid cycle to oxidative phosphorylation)? Account for all of them.
38 molecules of ATP total per molecule of glucose.
Per molecule of glucose, each process creates:
Glycolysis: creates 2 NADH, 2 ATP (net)
Pyruvate dehydrogenase complex: creates 2 NADH
Citric acid cycle: creates 6 NADH, 2 FADH2, 2 ATP
total: 10 NADH, 2 FADH2, 4 ATP
10 NADH = 3 ATP (from oxidative phosphorylation)
2 FADH2 = 4 ATP (from oxidative phosphorylation)
4 ATP = 4 ATP
total = 38 ATP per molecule of glucose
Which complexes in the electron transport chain are proton pumps?
Complexes 1, 3, 4
