Chapter 17 Chronic And End-Stage Kidney Disease Flashcards

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0
Q

The kidney disease outcome quality initiative defined five stages of kidney disease on the basis of what?

A

Glomerular Filtration rate, the presence of albuminuria.

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1
Q

A large percentage of all end-stage renal disease is attributed to what two things?

A

Diabetes and hypertension

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2
Q

In clinical practice the GFR is most commonly estimated by the calculated what?

A

Creatinine clearance

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3
Q

Risk factors for chronic kidney disease include?

A

Diabetes, hypertension, family history, advancing age, race (Black) diseases such as lupus, arterial sclerosis, and chronic NSAID use.

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4
Q

a decline in renal function remains asymptomatic until approximately what percent of nephrons are lost?

A

50%, usually in stage three.

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5
Q

How is stage five chronic kidney disease defined?

A

The patient will be in renal failure and need dialysis and have a GFR less than 15.

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6
Q

What signs and symptoms of renal failure might you expect to see any patient with a GFR between 20 and 50?

A

Elevated BUN and creatinine, metabolic acidosis, increased potassium, polyurea, anemia, and fatigue

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7
Q

What signs and symptoms of renal failure might you see in a patient with a GFR less than 20?

A

Decreased calcium, increased phosphate, metabolic acidosis, and fluid overload.

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8
Q

What signs and symptoms of renal failure might you expect to see in a patient with a GFR less than 10?

A

Uremia, nausea and vomiting, heart failure, pruritus, fatigue, and insomnia.

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9
Q

Patients with chronic kidney disease must be educated about the importance of controlling what?

A

Comorbidity disease processes such as hyperglycemia, hypertension, & Hyperlipidemia.

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10
Q

Most agencies have set the goal for hemoglobin A-1c at less then?

A

7

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11
Q

Target blood pressure to slow the progression of kidney disease is what?

A

Less then 130/80 And should be achieved with the use of ACE inhibitors or ARBs as part of the regimen.

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12
Q

Patients who reach stage III kidney disease and also have diabetes are more likely to die of what then to progress to stage five kidney disease?

A

Cardiovascular disease

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13
Q

The LDL cholesterol goal for patients and chronic kidney disease is what?

A

<70mg/dL In cases of patients who have cardiovascular events.

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14
Q

Teaching for patients with chronic kidney disease include….

A

Smoking cessation, exercise, dietary changes with sodium, protein, and potassium restrictions. Patients should be warned to avoid medications such as NSAIDs and to avoid dehydration.

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15
Q

What are the three classifications of acute renal failure?

A

Prerenal, intrinsic, Or post renal failure.

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16
Q

This type of renal failure is caused by a blockage after the level of the kidney. The most common cause is BPH in men. Other causes, such as stones or retroperitoneal tumors are much less common.

A

Post obstructive renal failure

17
Q

This type of renal failure can because by nephrotoxic Drugs, Contrast dye, hypertension, glomurulonephritis, lupus,cholesterol embolization.

A

Intrinsic renal failure

18
Q

This type of renal failure occurs as a result of decreased renal perfusion. Decreased blood flow caused by stenosis of the renal arteries or any type of hypovolemia, or any cause of reduced cardiac output,or shunts blood away from the kidneys such as shock. Also drugs that lower GFR such as NSAIDs.

A

Pre-Renal azotemia

19
Q

This is decreased red blood cells, hemoglobin and hematocrit and is a symptom of an underlying problem.

A

Anemia

20
Q

Common symptoms of anemia in older adults are?

A

Fatigue, pallor, and dizziness. In severe cases patients may present with mental status changes.

21
Q

Anemias are classified by what?

A

Red blood cell size or mean corpuscle volume MCV.

22
Q

If the MCV is within normal range, the anemia is considered what?

A

Normocytic anemia

23
Q

If the MCV is elevated, the RBC is large it is called?

A

Macrocytic anemia

24
Q

If the MCV is decreased And the red blood cell is small it is called?

A

Microcytic anemia

25
Q

Common causes of normocytic anemia include?

A

Acute blood loss, and anemia of chronic disease.

26
Q

Common causes of microcytic anemia include?

A

Iron deficiency anemia. Usually G.I. bleeding is the culprit so sources must be identified

27
Q

Common causes of macrocytic anemia include?

A

B 12 or folate deficiency. Inadequate intake or absorption of one or both of these nutrients

28
Q

Nursing management of anemia centers on what?

A

Dietary education and balancing rest with activities of daily living. Assessment includes focusing on the underlying cause of the anemia. Provide patient with a list of foods high in the nutrient they are deficient.

29
Q

This type of anemia is a complete lack of production of intrinsic factor and is rare in older adults As most have been diagnosed with this as young or middle adults.

A

Pernicious anemia

30
Q

What factors interfere with the absorption of B12 in older adults?

A

The parietal cells atrophy and make less hydrochloric acid and intrinsic factor. In addition use of acid suppressing medications such as histamine blockers and proton pump inhibitors, further suppress acid production which compromises the bodies ability to absorb B12 and other nutrients.

31
Q

An older person to have low vitamin B12 levels and macrocytic anemia who fail to have their levels rise with oral vitamin B12 replacement then what?

A

Parenteral B12 injections may be needed

32
Q

This is a malignant proliferation of white blood cell precursors, or blasts, in bone marrow.

A

Leukemia

33
Q

The most common leukemia and older adults is?

A

Chronic lymphocytic leukemia or CLL

34
Q

90% of cases of CLL occur in persons after the age of what?

A

Age 50 with an average age of diagnosis at age 70. Most older adults have a normal lifespan and do not succumb to this illness.

35
Q

Common symptoms of CLL include?

A

Weakness, fatigue, weight loss, splenomegaly, abdominal pain, fever, lymphadenopathy. Painless lymphadenopathy is the most common sign. Patients with CLL have a white blood cell count of 5000 to greater than 20,000/MCL

36
Q

What is the treatment for CLL?

A

There is no treatment for this illness. Patients are treated for symptoms if any occur. Radiation, chemotherapy, and splenectomy may be done. A small percentage of patients will convert to acute lymphocytic leukemia or ALL.

37
Q

This illness requires prompt treatment with chemotherapy or bone marrow transplant or the patient will succumb to it.

A

Acute myelogenous leukemia or AML. In most cases of AML, remission can be obtained, but many older adults will experience a relapse.

38
Q

Risk factors for leukemia are thought to be?

A

Advanced age and exposure to prolonged radiation.

39
Q

Diagnostic test for leukemia include?

A

Laboratory tests, bone marrow aspiration, and histochemical stains.

40
Q

Nursing management for patients with leukemia includes?

A

Pain control, education about activity intolerance, and prevention of infection.