Chapter 16 Robbins

Question 1

impairment of drainage of sinus by inflammatory edema of mucosa may impound suppurative exudate producing ___

Answer 1

empyema of sinus

Question 2

necrotizing lesions of the nose and upper airways caused by

Answer 2

GEF

granulomas with polyangiitis
Extranodal NK/T cell lymphoma, nasal type
fungal infection

Question 3

benign highly vascular tumor in red haired fair skinned young male in

Answer 3

nasopharyngeal angiofibroma

Question 4

singers nodules and polyps for reactive nodules, which is bilateral and uni

Answer 4

singers = bi
polyps = uni (smoking)

Question 5

do reactive nodules give rise to cancer

Answer 5

mostly never

Question 6

severe forms of chronic sinusitis are caused by

what population

Answer 6

fungi, mucomycosis

-higher prevelance in diabetics

Question 7

sinusitis is most commonly preceded by what

Answer 7

acute or chronic rhinitis

Question 8

in infants and young children with small airways laryngoepiglottiis from what can induce sudden swelling of epiglottis and constitiute a medical emergency

Answer 8

RSV, H influenza, b hemolytic strep

Question 9

small blue round cell neoplasm that arise from neuroectodermal olfactory cells in mucosa in superior aspect of nasal cavitity

Answer 9

olfactory neuroblastoma

Question 10

where does nasopharyngeal angiofibroma occur and what is the fatalaty rate

Answer 10

posterolateral wall of roof of nasal cavity

9% are fatal from hemorrhage and intracranial extension

Question 11

benign neoplasm arising from respiratory mucosa linging nasal cavity and paranasal sinuses

Answer 11

sinonasal papilloma

Question 12

nasal polyps are mainly atopic or non atopic

Answer 12

non atopic

Question 13

Nasopharyngeal carcinoma features

• demographic
• associated with
• whats almost always involved
• subtypes and worse prognosis

Answer 13

geographic distribution: children in africa, adults in china

• associated with EBV
• cervical LN involvement in 70% of cases
• keratinizing, nonkeratininzing, and undiff/basaloid variants
• keratininzing has worst surivival rate

Question 14

age for olfactory neuroblastoma

Answer 14

15 and 50 years old peak

Question 15

offending agent of sinusitits

Answer 15

normal inhabitiants of oral cavity

Question 16

sinusitis infection more serious complications

Answer 16

can spread to orbit or penetrate surruounding bone to give osteomyelitis

-can spread to cranial vault causing septic thrombophlebitis of dural venous sinus

Question 17

prognosis of NUT midline carcinoma

Answer 17

most pts die within a year

Question 18

this tumor is positive for enolase, synaptophysin, cd56, and chromogranin

Answer 18

olfactory neuroblastoma

Question 19

pharyngitis and tonsillitis are frequent features of what

Answer 19

viral URI
adenovirus, rhinovirus, echovirus

may have bacteria superimposed (group b strep most common, sometimes s aureus)

Question 20

benign neoplasm usually on true vocal cord that forms soft, rasperry like proliferation rarely more than 1 cm in diameter

-lesions caused by what

Answer 20

squamous papilloma and papillomatosis

caused by hpv 6 and 11

Question 21

chronic rhinitis

possible problem

Answer 21

sequel to repeated attacks of acute rhinitis with eventual development of superimposed bacterial infection

sometimes extend into the air sinuses

Question 22

3 forms of sinonasal papilloma (schneiderian)

• which is most aggressive
• associated with what
• can it be malignant and invade?

Answer 22

exophytic, endophytic, cylindrical
-endophytic most aggressive

HPV 6 and 11 (endo and exo)
-can invade orbit and cranial vault, malignant in 10% of cases

Question 23

cancer that maniefsts clincically as persistent hoarseness, dysphagia, and dysphonia most common males in 60s

Answer 23

carcinoma of the larynx

Question 24

obstruction of outflow most often from frontal sinus can lead to accumulation of mucous secretions producing

Answer 24

mucocele

Question 25

translocation with NUT

Answer 25

BRD4-NUT

Question 26

uncommon tumor of the nasopharynx or salivary gland

Answer 26

also other midline structures

NUT midline carcinoma

Question 27

extranodal nk/t cell lymphoma nasal type feature

Answer 27

lymphoma in which tumor cells harbor EBV
50s and 60s
Asians and Latin Americans

Question 28

hypersensitivity rxn to allergens in which leukocytic infiltration and eosinophils are prominent

Answer 28

allergic rhinitis

Question 29

recurrent attacks of _____ may eventually lead to focal protrusion of mucosa producing ____

Answer 29

rhinitis, polyps

Question 30

main causes of infectious rhinitis

Answer 30

ARE

Adenovirus
Rhinovirus
echovirus