Chapter 15: The Autonomic Nervous System Flashcards
What is the primary role of the autonomic nervous system (ANS)?
The ANS contributes to homeostasis by conveying motor output from the CNS to smooth muscle, cardiac muscle, and glands for appropriate responses to integrated sensory information.
What are the two main branches of the autonomic nervous system?
The two main branches of the ANS are the sympathetic nervous system and the parasympathetic nervous system.
What is the primary function of the somatic nervous system (SNS)?
The SNS controls voluntary movements by innervating skeletal muscles, with motor neurons causing muscle contractions.
How does the somatic nervous system operate in terms of control?
The somatic nervous system usually operates under voluntary (conscious) control, but some involuntary movements, such as posture and reflexes, are controlled by integrating centers in the brainstem and spinal cord.
How does the autonomic nervous system (ANS) differ from the somatic nervous system (SNS)?
The ANS regulates involuntary processes, such as the function of smooth muscle, cardiac muscle, and glands, while the SNS controls voluntary movements of skeletal muscles.
What are visceral effectors in the context of the autonomic nervous system?
Visceral effectors are tissues such as cardiac muscle, smooth muscle, and glands that are regulated by the ANS.
What is dual innervation in the autonomic nervous system?
Dual innervation refers to the fact that most organs receive input from both the sympathetic and parasympathetic divisions of the ANS.
What is the function of the sympathetic nervous system?
The sympathetic nervous system prepares the body for emergency situations, often referred to as the fight-or-flight response.
What is the function of the parasympathetic nervous system?
The parasympathetic nervous system enhances rest-and-digest activities, promoting body energy conservation and restoration during rest or digestion.
How does the enteric nervous system (ENS) function?
The ENS regulates the gastrointestinal tract, with sensory neurons monitoring chemical changes and stretching, and motor neurons controlling smooth muscle contractions and gland secretions.
What is the role of preganglionic and postganglionic neurons in the autonomic nervous system?
In the ANS, the preganglionic neuron extends from the CNS to an autonomic ganglion, and the postganglionic neuron extends from the ganglion to the effector tissue (smooth muscle, cardiac muscle, or a gland).
What is the difference between somatic and autonomic motor neurons in terms of neurotransmitter release?
Somatic motor neurons release acetylcholine (ACh) only, while autonomic motor neurons release either ACh or norepinephrine (NE).
What is the role of chromaffin cells in the autonomic nervous system?
Chromaffin cells, found in the adrenal medulla, secrete the neurotransmitters epinephrine and norepinephrine.
What is the key difference between the motor pathways in the somatic and autonomic nervous systems?
The somatic nervous system has a single motor neuron extending directly to the effector, while the autonomic nervous system typically involves two motor neurons in series.
What type of sensory input does the Somatic Nervous System (SNS) receive?
The SNS receives sensory input from somatic senses and special senses.
What type of sensory input does the Autonomic Nervous System (ANS) receive?
The ANS mainly receives sensory input from interoceptors, with some input from somatic senses and special senses.
What is the control of motor output in the Somatic Nervous System?
Motor output in the SNS is under voluntary control from the cerebral cortex, with contributions from the basal ganglia, cerebellum, brainstem, and spinal cord.
What is the control of motor output in the Autonomic Nervous System?
The ANS is under involuntary control from the hypothalamus, limbic system, brainstem, and spinal cord, with limited control from the cerebral cortex.
What is the motor neuron pathway in the Somatic Nervous System?
The SNS has a one-neuron pathway: Somatic motor neurons extend from the CNS and synapse directly with the effector.
What is the motor neuron pathway in the Autonomic Nervous System?
The ANS usually follows a two-neuron pathway: Preganglionic neurons extend from the CNS to an autonomic ganglion, and postganglionic neurons extend from the ganglion to the effector. Alternatively, preganglionic neurons may synapse with chromaffin cells in the adrenal medullae.
What neurotransmitters are released in the Somatic Nervous System?
All somatic motor neurons release only acetylcholine (ACh).
What neurotransmitters are released in the Autonomic Nervous System?
All sympathetic and parasympathetic preganglionic neurons release ACh. Most sympathetic postganglionic neurons release norepinephrine (NE); those to most sweat glands release ACh. All parasympathetic postganglionic neurons release ACh. Chromaffin cells of the adrenal medullae release epinephrine and norepinephrine (NE).
What are the effectors of the Somatic Nervous System?
The effectors of the SNS are skeletal muscles.
What are the effectors of the Autonomic Nervous System?
The effectors of the ANS are smooth muscle, cardiac muscle, and glands.
What is the response to motor output in the Somatic Nervous System?
The response in the SNS is the contraction of skeletal muscles.
What is the response to motor output in the Autonomic Nervous System?
The response in the ANS includes contraction or relaxation of smooth muscle, increased or decreased rate and force of contraction of cardiac muscle, and increased or decreased secretions of glands.
What are the two motor neurons in any autonomic motor pathway called?
The two motor neurons are called the preganglionic neuron and the postganglionic neuron.
Where is the cell body of a preganglionic neuron located?
The cell body of a preganglionic neuron is in the brain or spinal cord.
What is the axon of a preganglionic neuron like?
The axon of a preganglionic neuron is a small-diameter, myelinated type B fiber.
Where does the preganglionic neuron synapse?
The preganglionic neuron synapses with a postganglionic neuron in an autonomic ganglion.
What is the axon of a postganglionic neuron like?
The axon of a postganglionic neuron is a small-diameter, unmyelinated type C fiber.
Where does the axon of a postganglionic neuron terminate?
The axon of a postganglionic neuron terminates in a visceral effector.
What are the two divisions of the autonomic nervous system based on the location of preganglionic neurons?
The two divisions are the sympathetic division (thoracolumbar division) and the parasympathetic division (craniosacral division).
Where are the preganglionic neurons of the sympathetic division located?
The preganglionic neurons of the sympathetic division are located in the lateral horns of the gray matter in the 12 thoracic segments and the first two lumbar segments of the spinal cord.
Where are the preganglionic neurons of the parasympathetic division located?
The preganglionic neurons of the parasympathetic division are located in the nuclei of four cranial nerves (III, VII, IX, and X) in the brainstem and in the lateral gray matter of the second through fourth sacral segments of the spinal cord.
What are the two major types of sympathetic ganglia?
The two major types of sympathetic ganglia are sympathetic trunk ganglia and prevertebral ganglia.
Where are sympathetic trunk ganglia located?
Sympathetic trunk ganglia are located in a vertical row on either side of the vertebral column, extending from the base of the skull to the coccyx.
Where are prevertebral ganglia located?
Prevertebral ganglia are located anterior to the vertebral column, close to large abdominal arteries.
Where do preganglionic axons of the parasympathetic division synapse?
Preganglionic axons of the parasympathetic division synapse with postganglionic neurons in terminal (intramural) ganglia, located close to or within the wall of a visceral organ.
How many postganglionic neurons may a single sympathetic preganglionic fiber synapse with?
A single sympathetic preganglionic fiber may synapse with 20 or more postganglionic neurons.
What are the types of connections between sympathetic preganglionic neurons and postganglionic neurons?
- Synapse with postganglionic neurons in the same ganglion. 2. Ascend or descend to a higher or lower ganglion before synapsing. 3. Continue without synapsing to a prevertebral ganglion. 4. Pass through ganglia and synapse with chromaffin cells in the adrenal medullae.
How does the parasympathetic division affect its effectors?
The parasympathetic division usually causes localized responses, with each postganglionic neuron synapsing with only four or five postsynaptic neurons that supply a single visceral effector.
What are autonomic plexuses?
Autonomic plexuses are tangled networks of both sympathetic and parasympathetic neurons in the thorax, abdomen, and pelvis, often along major arteries, sometimes containing sympathetic ganglia.
What are the major autonomic plexuses in the thorax?
The major autonomic plexuses in the thorax are the cardiac plexus, which supplies the heart, and the pulmonary plexus, which supplies the bronchial tree.
What is the celiac (solar) plexus?
The celiac (solar) plexus is the largest autonomic plexus, surrounding the celiac trunk, and it supplies organs such as the stomach, spleen, pancreas, liver, gallbladder, kidneys, adrenal medullae, testes, and ovaries.
What organs are supplied by the superior mesenteric plexus?
The superior mesenteric plexus supplies the small and large intestines.
What organs are supplied by the inferior mesenteric plexus?
The inferior mesenteric plexus supplies the large intestine.
What is the role of the renal plexus?
The renal plexus supplies the renal arteries within the kidneys and ureters.
Where are the sympathetic preganglionic neurons located?
The cell bodies of sympathetic preganglionic neurons are located in the lateral gray horns of all thoracic segments and the first two lumbar segments of the spinal cord.
How do sympathetic preganglionic axons travel to the sympathetic trunk?
The preganglionic axons travel through the anterior root of a spinal nerve, enter a white ramus, and then pass to the nearest sympathetic trunk ganglion.
What is the function of white rami communicantes?
White rami communicantes contain myelinated sympathetic preganglionic axons and connect the anterior ramus of a spinal nerve with the ganglia of the sympathetic trunk.
How many sympathetic trunk ganglia are there?
There are 3 cervical, 11 or 12 thoracic, 4 or 5 lumbar, 4 or 5 sacral sympathetic trunk ganglia, and 1 coccygeal ganglion.
What do the postganglionic neurons of the superior cervical ganglion innervate?
Postganglionic neurons from the superior cervical ganglion innervate the sweat glands, smooth muscles of the eye, blood vessels of the face, lacrimal glands, pineal gland, nasal mucosa, salivary glands, and the heart.
What is the sympathetic innervation of the heart?
Sympathetic innervation of the heart consists of postganglionic neurons from the cervical and thoracic ganglia that enter the cardiac plexus to supply the heart.
What is the sympathetic innervation of the lungs?
Sympathetic innervation of the lungs involves postganglionic neurons from the thoracic ganglia that enter the pulmonary plexus to supply the smooth muscle of the bronchi and bronchioles.
What are splanchnic nerves?
Splanchnic nerves are formed by sympathetic preganglionic axons that pass through the sympathetic trunk and extend to prevertebral ganglia, supplying the organs of the abdominopelvic cavity.
What is the role of splanchnic nerves to the suprarenal medulla?
Splanchnic nerves to the suprarenal medulla stimulate chromaffin cells in the adrenal glands to release hormones, mainly epinephrine, norepinephrine, and a trace of dopamine.
Where are parasympathetic preganglionic neurons located?
Parasympathetic preganglionic neurons are found in the nuclei in the brainstem and the lateral gray matter of the second through fourth sacral segments of the spinal cord.
What is the cranial parasympathetic outflow?
The cranial parasympathetic outflow consists of preganglionic axons that extend from the brainstem in four cranial nerves.
What are the four pairs of cranial parasympathetic ganglia?
The four pairs of cranial parasympathetic ganglia are the ciliary, pterygopalatine, submandibular, and otic ganglia.
Where is the ciliary ganglion located, and what does it innervate?
The ciliary ganglion is located lateral to the optic nerve near the posterior orbit. It innervates smooth muscle fibers in the eyeball.
Where is the pterygopalatine ganglion located, and what does it innervate?
The pterygopalatine ganglion is located lateral to the sphenopalatine foramen, between the sphenoid and palatine bones. It innervates structures in the head such as the lacrimal glands and mucosal glands.
What are the two classifications of autonomic neurons based on the neurotransmitter they produce and release?
Autonomic neurons are classified as cholinergic or adrenergic based on the neurotransmitter they produce and release.
What neurotransmitter do cholinergic neurons release?
Cholinergic neurons release acetylcholine (ACh).
Which autonomic neurons are cholinergic?
Cholinergic neurons include: 1) all sympathetic and parasympathetic preganglionic neurons, 2) sympathetic postganglionic neurons that innervate sweat glands, and 3) all parasympathetic postganglionic neurons.
What are the two types of cholinergic receptors?
The two types of cholinergic receptors are nicotinic receptors and muscarinic receptors.
Where are nicotinic receptors located?
Nicotinic receptors are located in the plasma membrane of dendrites and cell bodies of sympathetic and parasympathetic postganglionic neurons, chromaffin cells of the adrenal medullae, and the motor end plate at the neuromuscular junction.
Where are muscarinic receptors located?
Muscarinic receptors are located in the plasma membranes of effector cells (smooth muscle, cardiac muscle, and glands) innervated by parasympathetic postganglionic axons and in sweat glands innervated by cholinergic sympathetic postganglionic neurons.
What effect does ACh have on nicotinic receptors?
Activation of nicotinic receptors by ACh causes depolarization and excitation of the postsynaptic cell.
What effect does ACh have on muscarinic receptors?
Activation of muscarinic receptors by ACh can cause either depolarization (excitation) or hyperpolarization (inhibition), depending on the cell.
What enzyme inactivates acetylcholine (ACh)?
Acetylcholine is inactivated by the enzyme acetylcholinesterase (AChE).
What neurotransmitter do adrenergic neurons release?
Adrenergic neurons release norepinephrine (NE), also known as noradrenaline.
What are the two main types of adrenergic receptors?
The two main types of adrenergic receptors are alpha (α) receptors and beta (β) receptors.
What are the subtypes of adrenergic receptors?
The subtypes of adrenergic receptors are α1, α2, β1, β2, and β3.
What is the typical effect of activation of α1 and β1 receptors?
Activation of α1 and β1 receptors generally produces excitation.
What is the typical effect of activation of α2 and β2 receptors?
Activation of α2 and β2 receptors generally causes inhibition of effector tissues.