Chapter 15 - Evidence For Evolution Flashcards

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1
Q

How are genes gained or lost?

A

New genes are gained by mutation.

Other genes are lost by natural selection, random genetic drift etc.

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2
Q

Species that are more distantly related have…

A

More differences in their DNA, where as species that are more closely related share a greater portion of DNA.

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3
Q

Define genome

A

The complete set of genetic material within a cell ; an organisms complete set of DNA.

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4
Q

How much of a DNA difference is there between humans, chimpanzees, gorillas and orang-utans.

A

Human and chimpanzee = share 98.8%, thus 1.2% difference

Human and gorilla = share 98.4%, thus have a 1.6% difference

Human and organ-utan = share 97.6%, thus have a 2.4% difference

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5
Q

What is the difference between human chromosomes and chimpanzee chromosomes?

A

Chimpanzees have 24 pairs of chromosomes while humans have 23. It is believed that two small chromosomes in chimpanzees happened to fuse together in humans at some time in the past.

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6
Q

Define junk DNA.

A

Non-coding sequences of nucleotides in DNA. They have no apparent function and appear to serve no purpose.

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7
Q

What does ERV stand for and what is it?

A

ERV are endogenous retroviruses which are viral sequences that have become part of an organisms genome. They are also referred to stretches of non - functional DNA.

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8
Q

Explain the process of ERVS entering cells.

A

Retroviruses store their genetic information as RNA not DNA.
Upon entering a cell, a retrovirus copies it’s RNA into DNA (a process called reverse transcription).
The DNA then becomes endogenous if it inserts into germinal cells/ gametes.
The offspring of the infected individual will then have a copy of the ERV at the same location, in the same chromosome, in every single one of their cells.
ERVS make up 8% of the human genome.

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9
Q

What is mitochondrial DNA? And how many are there?

A

Mitochondrial DNA are small, circular molecules of DNA found in the mitochondria of a cell. There are about five to ten of these molecules in each mitochondrion.

Most cells contain large numbers of mitochondria and usually gave between 500-1000 copies of the mtDNA molecule. In humans, the mt DNA genome consists of about 16500 base pairs.

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10
Q

How many genes are in mtDNA?

A

MtDNA has 37 genes.
24 - containing the code for making transfer RNA molecules.
13 - have instructions for making enzymes necessary for cellular respiration.

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11
Q

How is mitochondrial DNA passed on?

A

Mitochondrial DNA is passed on by maternal ancestors, as male mtDNA are destroyed after entering the cell.

We inherit nuclear DNA from our parents but we inherit mitochondrial DNA only from our mothers.

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12
Q

What are two ways mtDNA has contributed to understanding evolution?

A
  • scientists can compare the mtDNA of any two individuals to provide an estimate of the closeness of their relationship through their maternal ancestors.
  • scientists are able to trace migration routes of ancient people.
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13
Q

How many kinds of amino acids are there?

A

20 kinds of amino acids.

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14
Q

How can protein sequences be used to understand evolution?

A
  • Animals of the same species have the same amino acid sequences in their proteins.
  • Animals of different species have different amino acids or they are arranged in a different order.
  • The longer the period of time involved, the greater the number of amino acids that are different.
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15
Q

List the 20 different amino acids and their single letter codes.

A
Alanine A 
Arginine R
Asparagine N
Asparagine D 
Aspartic acid D
Cysteine C
Glutamic acid E
Glutamine Q
Glycine G
Histidine H
Isoleucine I
Leucine L
Lysine K
Methionine M
Phenylalanine F
Proline P
Serine S
Threonine T
Tryptophan W
Tyrosine Y
Valine V
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16
Q

What is cytochrome C?

A

Cytochrome C is a well-researched example of a ubiquitous protein that shows how protein sequences can provide evidence for evolution.
It is essential in producing cellular energy.

17
Q

How many amino acids are in Cytochrome C?

A

104 amino acids.

18
Q

What is bioinformatics?

A

The use of computers to describe and understand biological processes
It involves computer science, statistics and applied mathematics.

19
Q

What is annotation?

A
  • This process needs to be computerised as most genomes are far too large to be annotated by hand.

The computerised process of identifying genes and other biological features in a DNA sequence.

20
Q

How is annotation possible?

A

By the fact that genes have recognisable start and stop codons.

21
Q

What is comparative genomics?

A

Comparative genomics is a field of biological research in which the genome sequences of different species are compared.

22
Q

What has comparative genomics revealed about evolution? (Hint 2)

A
  • revealed a high level of similarity between closely related organisms (humans and chimpanzees)
  • reveals the diversity of gene composition.
23
Q

What is comparative studies in anatomy?

A

Comparative anatomy involves comparing the structural features of related organisms to identify how similar they are.

24
Q

What are the three main areas of comparative anatomy?

A
  • Embryology : comparing the very early stages of organisms.
  • Homologus organs : organs that are similar in structure but are used differently by different animals.
  • Vestigal organs : organs that have no function.
25
Q

Define embryology.

A

Embryology is the study of the early development of an organism. In humans it’s from fertilisation until the 8th week of pregnancy.

26
Q

What are the five species that have gill pouches and arches during early embryonic stages?

A

Fish, reptiles birds, pigs, humans.

27
Q

In humans, what do gills develop into?

A

One gill develops into the Eustachian tube and tissue surrounding the other gill slits develop into the thyroid gland and tonsils.

28
Q

Define homologous organs.

A

Organs with similar structure but not necessarily similar function.

29
Q

Define vestigal organs.

A

Organs that have lost their original function in an organism but remains in the body. This is because they are harmless.

30
Q

How many vestigal organs do humans have?

A

Humans have as many as 90 of these structures.

31
Q

What is the nictitating membrane?

A

The nictitating membrane is the transparent third eyelid, found in cats, birds, frogs and other vertebrates. It is located at the inner corner of each eye.

32
Q

What are some examples of vestigal organs in humans?

A

The appendix, body hair, male nipples and the muscles that move the ears.

33
Q

Explain and give an example of geographical distribution.

A

Geographical distribution is when species adapt to their environment through natural selection.

  • During his time in South America, Charles Darwin encountered mainland finches and Galapagos island finches .
  • For some reason or another one species of finch managed to fly to the islands.
  • They took advantage of the food sources and their beaks evolved depending on the type of food they ate.
  • Eventually they evolved into 13 different species.
34
Q

What are some factors of biochemistry? Eg what does it involve? (DNA)

A
  • Junk DNA
  • Endogenous retroviruses
  • Mitochondrial DNA
  • Protein sequences
  • cytochrome C
35
Q

What are some factors of genomics? Eg what does it involve?

A
  • Protein sequencing
  • Aligning sequences
  • Cytochrome C
36
Q

What are some factors of bioinformatics? Eg what does it involve?

A
  • Annotation
  • DNA sequencing
  • DNA profiling
  • PCR
37
Q

What are some processes involved in comparative genomics and comparative biochemistry? (4)

A
  • Aligning sequences of different organisms to identify patterns.
  • Comparing DNA sequences between organisms.
  • Creating DNA profiles for certain organisms of the same species.
  • Annotating genes and other biological features in a DNA sequence
38
Q

What are 4 benefits of using comparative genomics, biochemistry and bioinformatics?

A
  1. Increases our basic knowledge of evolutionary pathways of related species.
  2. Helps out understanding the genetic basis of disease in all organisms.
  3. Helps us find new medical treatments to benefit human health.
  4. To determine the function of human genes.