Chapter 15 Flashcards
A part of a cell in a living thing that controls what it looks like, how it grows, and how it develops
Gene
A disease that is caused by an abnormality in an individual’s SNA
Genetic Disorder
An organism that does not cause disease itself, but which carry the DNA from one host to another.
Vector
a gene that does not work properly
Defective gene
are treated by repairing the damaged gene responsibile for the disease.
Genetic Diseases
Through the introduction of a normal copy of the gene instead of using drugs or surgery, the cells can produce the normal function protein.
Gene Therapy
The therapeutic genes are placed inside a harmless virus, where most of its own genes are removed or deactivated. This virus works by entering into the cell, taking over its DNA and forcing it to produce more viruses.
Use of Vector
are a class of undifferentiated cells that are able to differentiate into specialized cell types. They are the foundation for every organ and tissue in the body. Have the potential to develop into cells with different functions.
Stem Cells
Are then manipulated in the laboratory to accept new genes that can then change their characteristics. Thus, when they grow, divide, and differentiate they already carry the manipulated genes that would enable them to treat the disease.
Stem Cells
Two types ot Gene Therapy
Somatic Gene Therapy
Germline gene therapy
If the cell to be treated is any cell of the body aside from sperm or egg cell.
Somatic Gene therapy
When the cells used are either sperm or egg cells
Germline gene therapy
Categories of Gene Therapy
- Ex Vivo gene therapy
- In Vivo Gene Therapy
Genetic manipulation of cells is done outside the body, which is well suited in targeting a specific organ rather than treating the whole organism.
Ex Vivo gene therapy
Involves the direct introduction of the genetic materials into the human body.
In Vivo gene therapy
