Chapter 15 & 16 - Veins & Microcirculation Handout Flashcards

0
Q

Total amount of blood that can be stored in a given portion of circulation per ml of mercury rise in pressure.

A

Compliance

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1
Q

Ability of a certain vessel type to accomodate blood and change its caliber.

A

Distensibility

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2
Q

Mechanism that compensates when there is an increase in blood pressure volume

A

Stress Relaxation or Delayed Compliance

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3
Q

Pressure in the RA where blood from all peripheral veins empty

A

Central venous pressure (CVP) or R Atrial pressure

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4
Q

Two major factors that affects pulse pressure

A
  1. Stroke volume output of the heart.
  2. Compliance (total distensibility) of the atrial tree

Less important factor:
Character of ejection from the heart during systole

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5
Q

What is the normal value of the right atrial pressure?

A

0 mm Hg

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7
Q

Normal value of arterial pressure?

A

100 mm Hg

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8
Q

True or False:

The heart acts as a feedback regulator of pressure at the tricuspid valve.

A

True

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9
Q

True or False:

60% of all the blood in the circulatory system is usually in the arteries.

A

False.

usually in the VEINS

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10
Q

Korotkoff sounds is named after ______. A russian physician who described them in 1905.

A

Nikolai Korotkoff

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11
Q

It is the average ofthe arterial pressures measured millisecond by millisecond over a period of time.

A

Mean Arterial Pressure

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12
Q

Other name for venous pump

A

Muscle pump

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13
Q

True or False:

The venous system serves as blood reservoirs for the circulation.

A

True

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14
Q

Specific blood reservoirs

A

Spleen
Liver
Large abdominal veins
Venous plexus beneath the skin

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15
Q

A “specific blood reservoir” which decrease in size sufficiently to release as much as 100 millimeters of blood into other areas of circulation.

A

Spleen

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16
Q

True or False:

Heart and lungs as blood reservoirs.
The heart shrinks during sympathetic stimulation thus contribute 50-100 ml of blood, the lungs can contribute another 100-200 ml when the pulmonary pressures decrease to low values.

A

True

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17
Q

Two areas in the spleen for storing blood.

A
  1. Venous sinuses

2. Pulp

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18
Q

It is a special reservoir in the spleen that contains large quantities of concentrated red blood cells.

A

Red pulp of the spleen

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19
Q

An area in the spleen that manufacture lymphoid cells

A

White pulp of the spleen

20
Q

Main purpose of circulatory system

A
  1. Transport of nutrients to cell

2. Removal of cell excreta

21
Q

Intermittent flow of blood in the capillaries through the contraction of the metarteriole and precapillary sphincter.

A

Vasomotion

22
Q

What can pass through the tight junctions in the brain?

A

Only water, O2 and CO2

23
Q

True or False:

Blood usually does not flow continuously through the capillaries.

24
Q

Most important factor for degree of opening and closing in vasomotion.

A

Oxygen concentration.

Low o2 in tissues –> more frequent and prolonged flow of blood

25
Lipid soluble (O2, CO2, etc) diffuse through _____.
Capillary wall
26
Water-soluble substances (Na, Cl, glucose) pass through _____.
Cleft pore
27
In the capillary wall, majority of transport happens in the _____.
Intercellular cleft
28
In the capillary membrane,the most important means by which substances are transferred between the plasma and the interstitial fluid is ____.
Diffusion. Diffusion results from thermal motion of the water molecules amd dissolved substances in the fluid.
29
2 small passages connecting the interior of capillary with the exterior
1. Intercellular cleft | 2. Plasmalemmal vesicles / calveolae
30
What fraction of total body fluid does the interstitium take?
1/6
31
In the capillary, diffusion results from ____ & ____.
1. Thermal motion of water molecules | 2. Dissolved substances in the fluid
32
What determines fluid filtration across capillaries?
1. Hydrostatic Pressure 2. Colloid Osmotic Pressure 3. Capillary Filtration Coefficient
33
This normally prevents significant loss of fluid volume from blood into the interstitial spaces.
Colloid Osmotic Pressure (exerted by plasma proteins).
34
Movement of fluid through capillary pores goes to interstitial fuid.
Hydrostatic Pressure
36
Fluid movement by osmosis from interstitial spaces into blood.
Colloid Osmotic Pressure
38
This system returns to the circulation the small amounts of excess protein & fluid leak from the blood into the interstitial spaces.
Lymphatic System
39
Starling's Forces: This tends to force fluid outward through capillary membrane.
Capillary Pressure
40
Starling's Forces: Tends to force fluid inward when Pif is (+) and outward if Pif is (-)
Interstital Fluid Pressure
41
Tends to cause osmosis of fluid inward through capillary membrane
Capillary Plasma Colloid Osmotic Pressure
42
Tends to cause osmosis of fluid outward through capillary membrane
Interstitial fluid Colloid Osmotic Pressure
43
If sum of starling's forces is (-) there will be a net ____ from interstitial spaces into capillaries.
Fluid absorptiom
44
If sum of starling's forces is (+) there will be a net _____ across capillaries.
Fluid filtration
45
Primary forces that determine whether fluid will move out of the blood into the interstitial fluid or in opposite direction.
Starlings's forces
46
Give the 4 Starling's forces.
1. Capillary Pressure (Pc) 2. Interstitial Fluid Pressure (Pif) 3. Capillary Plasma Colliod Osmotic Pressure (IIp) 4. Interstitial Fluid Colloid Osmotic Pressure (IIif)
47
Measure of capacity of the capillary membranes to filter water for a given Net Filtration Pressure.
Capillary Filtration Coefficient (Kf)
48
2 primary factors that determine lymph flow
1. Interstitial Fluid Pressure | 2. Activity of Lymphatic Pump