Chapter 14 reactions Flashcards
1
Q
Alkene to epoxide
A
peroxyacid epoxidation, MCPBA
2
Q
ether to 2alkyl halides
A
Cleavage of ether by excess H-X
3
Q
Alkene to ether
A
Alkoxymercuration HgOAc2, R-OH, NaBH4
4
Q
Alcohol to ether
A
Williamson-ether synthesis, Na+, R-X or R-OTs
5
Q
epoxide to alkoxy alcohol
A
Acid catalyzed opening of epoxide using ROH
6
Q
Alkene to Halohydrin to epoxide
A
Cylization of Halohydrin, Br2 +H2O to form halohydrin, then strong base to form epoxide.
7
Q
Alcohol to alkoxide
A
Na+ metal
8
Q
Synthesis of sulfide
A
Thiolate ion as nucleophile in williamson ether synthesis
9
Q
acid catalyzed epoxy-opening using HX
A
10
Q
Acid catalyzed opening in water
A
11
Q
epoxide opening with organometallics
A
12
Q
base catalyzed opening with alkoxide
A
13
Q
base promoted cyclization of halohydrins
A
