Chapter 13- ANS Flashcards
Basic functions of the nervous system
- balance
- survival
- control
- pleasure and enjoyment
- cognitive ability
Divisions of peripheral nervous system
Sympathetic and parasympathetic
Sympathetic division
- fight or flight
- heart rate and blood pressure increase
- more blood goes to skeletal muscles
- liver produces more glucose
- bronchi dilate=more air into lungs
- pupils dilate=better vision
- ADRENERGIC
Parasympathetic division
- nonstressful conditions
- rest and digest response
- heart rate and blood pressure decline
- bronchi constrict
- CHOLINERGIC
explain process of synaptic transmission
AND
The neurotransmitters important to the autonomic nervous system
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What is the response when a drug activates alpha-1&2 receptors?
- arteriole constriction
- pupil dilation
- GI smooth muscle relaxation
What is the response when beta 1 receptors are activated?
- increased heart rate and force of contraction
- release of renin
What is the response when beta 2 receptors are activated?
- bronchodilation
- arteriole constriction
- glycogenolysis (breakdown of glycogen to glucose)
Therapeutic uses of adrenergic drugs
- bronchospasms
- asthma
- nasal and sinus congestion
Contraindications for ADRENERGIC agents
- narrow angle glaucoma
- heart disease,CAD, arrhythmias, CHF, peripheral vascular disease
Examples of ADRENERGIC drugs
- epinephrine/norepinephrine
- phenylphrine
- dopamine
- albuterol
- sudafed
ADRENERGIC agents mechanism of action
- mimic SNS
- work directly or indirectly or both via receptor sites and neurotransmitters
- generally the emergency medication (to maintain life during a crisis)
Adverse effects of ADRENERGIC agents
- nervousness
- dysrhythmias
- hypertension
- cardiac ischemia
- elevated glucose levels
- pupil dilation
- tissue necrosis
- headache, insomnia
- GI and bladder involvement
Responses that occur when drugs activate nicotinic receptor
- Stimulation of smooth muscle and gland secretions
- brain (memory learning)
Responses that occur when drugs activate muscarinic receptors
- Decreased heart rate and force of contraction
- stimulation of smooth muscle and gland secretions