Chapter 12 The Cell Cycle Flashcards

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1
Q

how do cells replicate

A
  1. copy chromosome, separate copies, divide the cytoplasm to generate daughter cells that have the same chromosomal complement to the parent cell
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2
Q

how do eukaryotic cells divide

A

the cells cycle through interphase and M phase

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3
Q

what happens during interphase

A

S (synthesis) Phase: chromosomes replicate

G1 and G2 Phases: cells grow and prepare for division

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4
Q

what happens during M phase

A

mitosis or meiosis, when chromosome separate, and the parent cell divides

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5
Q

Prophase

A

chromosomes condense, spindle apparatus begins to form, polar microtubule over lap each other

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6
Q

Prometaphase

A

nuclear envelope my dissolve, microtubules attach to the kinetochores of the chromosomes, which begin moving to the beginning of the spindle

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7
Q

Metaphase

A

All the chromosomes are positioned in the middle of the spindle, the spindle is anchored to the plasma membrane by astral microtubules

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8
Q

Anaphase

A

Sister chromatids are pulled apart by the disassembly of the kinetochore micro tubules at the kinetochore. The separated chromatids are now daughter chromatids. the spindle poles disintegrate at the positive end to further separate the replicated chromosomes

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9
Q

Telophase

A

daughter chromosomes are fully separated and are clustered at opposite poles of the spindle. A nuclear envelope forms around each set and the chromosome decondense

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10
Q

cancer

A

general term for a disease resulting from cells dividing in an uncontrolled fashion

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11
Q

cleavage furrow

A

where cytokinesis begins in eukaryotic cells

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12
Q

binary fission

A

how bacterial cells divide

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13
Q

M phase promoting factor

A

MPF induces M phase in all eukaryotes, made up of kinase and cyclins

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14
Q

kinase

A

an enzyme that catalyzes the transfer of a phosphate groups, the cyclin dependent kinase is a subunit of the MPF

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15
Q

cyclins

A

family of proteins whose concentrations fluctuate throughout the cell cycle. cyclin concentrations build during interphase and peak during M phase

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16
Q

G1 checkpoints

A
pass if: 
cell size is adequate
nutrients are sufficient
social signals are present
DNA is undamaged
17
Q

G2 checkpoint

A

pass if
chromosomes have replicated successfully
DNA is undamaged
activated MPF is present

18
Q

M Phase checkpoints

A

Pass if
chromosomes have attached to spindle apparatus
chromosomes have properly segregated and MPF is absent

19
Q

negative feedback

A

when a process is slowed or stopped by one of its products

20
Q

tumor

A

formed by cells that keep dividing due to issues with cell cycle checkpoints

21
Q

chromosome

A

a structure containing genetic information in the form of genes

22
Q

chromatin

A

the material tht makes up the eukaryotic chromosomes, consists of a DNA molecule complexed with histone proteins

23
Q

Chromatid

A

one double stranded DNA copy of a replicated chromosome with its associated proteins

24
Q

Sister chromatids

A

the 2 attached, double stranded DNA copies of a replicated chromosome, When chromosomes are replicated, they consist of two replicated chromosomes, the genetic material in the sister is identical, whe they separate during mitosis, they become independent chromosomes

25
Q

Centromere

A

a specialized region of a chromosome where sister chromatids are most closely joined to each other

26
Q

microtubule organizing center

A

any structure that organizes microtubules

27
Q

centrosome

A

the microtubule organizing center in animals and certain type of plants and fungi

28
Q

centrioles

A

cylindrical structures consisting of microtubule triplets, located inside animal centrosomes

29
Q

spindle apparratus

A

structure that produces mechanical forces that move replicated chromosomes during early mitosis and pull chromatids apart in late mitosis

30
Q

cell division

A

the splitting of preexisting cells

31
Q

embryos

A

newly developing organisms confirmed cell division

32
Q

meiosis

A

leads to production of sperma nd eggs

33
Q

mitosis

A

leads to production of ssomatic cells

34
Q

somatic cells

A

body cells