Chapter 12 Pt 1 Flashcards
Function of cell division
reproduction
Growth and development
Tissue renewal
Genome
All of the genetic material in an organism
-DNA is organized into chromosomes
Chromosomes
A cellular structure composed of a single long DNA molecule and associated proteins
-proteins are important for coiling and folding of DNA
Chromatin
DNA+Proteins
Chromosome organization in prokaryotes
DNA is found in the Nucleoid region
- not membrane-bound
- single circular chromosome
- less DNA
- may have plasmids
Plasmids
- small, circular DNA molecule
- few genes
- replicate independently
Cell division in prokaryotes
- replicate by binary fission
- before a cell can divide, it must grow larger and replicate its DNA
Chromosome organization in eukaryotes
- DNA enclosed nucleus
- multiple linear chromosomes
- more DNA
- humands have 46 chromosomes in their somatic cells
- 23 chromosomes in human gametes (sperm and egg)
Cell division in eukaryotes
Mitosis: nuclear division
-cells accurately and precisely segregate chromosomes to daughter cells
Cytokinesis: division of cytoplasm
Cell division
The reproduction of cells
-produces two genetically identical daughter cells from one parent cell
The cell cycle
Interphase:
G1: cell grows by producing more proteins, organelles, lipids, etc.
S phase: chromosomes are duplicated
G2: cell grows more and prepares to divide
M-phase:
Mitosis: division of nucleus
Cytokinesis: division of the cytoplasm
Sister chromatids
Identical copies of each chromosome
-held together at centromere by cohesion proteins
Sister chromatids separate during mitosis
During mitosis:
- cohesion proteins are degraded
- the sister chromatids segregate to become individual chromosomes
- pulled to opposite sides of the microtubules
Before mitosis begins
- DNA and cent roomed have been duplicated
- nuclear envelope is intact
Centrosomes
Microtubules organizing center
-each Centrosomes has a pair of centrioles