Chapter 12 | Biopharmaceutical Drug Development Flashcards
What is one way in which large molecule drugs differ from small molecule drugs?
Large molecule drugs are mainly protein-based drugs that develop in biological systems such as living cells.
Vaccines are types of small molecule drugs.
False
What is an advantage of attenuated vaccines over inactivated vaccines?
Attenuated vaccines are less expensive to prepare.
How are toxoids derived?
From the toxins secreted by a pathogen.
What is the estimated annual death toll in Malaria?
1.5 to 3.5 million people.
There are more white blood cells than red blood cells for the same volume in the human body.
False
How was insulin primarily obtained from the 1930s to the 1980s?
Porcine and bovine extracts.
Which of the following are not types of cytokines
a) interferons
b) interleukins
c) monokines
d) all of these are types of cytokines?
All of these are types of cytokines.
Which of the following is not a type of hormones
a) amino acid derivatives
b) blood glucose
c) polypeptides
d) steroids
b) blood glucose
Describe the ‘in vitro’ gene therapy technique.
Patients’ genetically faulted tissues are removed, loaded with normal genes in vectors, and returned to the patients’ bodies.
Pluripotent stem cells can develop into many cell types, but not a new individual.
True
Leukemia is a condition in which the stem cells in the bone marrow malfunction and produce an excessive number of immature white blood cells.
True
Retroviruses are types of vectors used in gene therapy.
True
Which of the following is not a type of stem cell a) multipotent
b) pluripotent
c) semipotent
d) totipotent
c) semipotent
Traditional vaccines are prepared in a number of ways. Which of the following is not one of them
a) attenuated
b) insulin
c) inactivated
d) toxoids
b) insulin
