Chapter 12 Flashcards
1
Q
Biology central dogma
A
DNA -> transcription -> RNA -> translation -> protein
Gene expression = transcription + translation
2
Q
How does epigenetics regulate gene expression
A
histone modification up-regulates (activates) or down-regulates (silences) gene expression
3
Q
When is regulation doen in pro vs. eu
A
Pro
- mostly during transcription
Eu
- post-translational modifications
4
Q
Constitutive transcription
A
constant expression of genes
- no regulatory control
5
Q
Regulated transcription
A
expression only occurs under certain conditions
(ex. food scarcity)
6
Q
Posttranscriptional regulation
A
After mRNA is synthesized, its abundance can be modified to influence the amount of protein translated
7
Q
Thermostat analogy (regulated expression)
A
- waste of energy for thermostat to always be ON
- so keep OFF by default unless too hot/cold = turn ON
this is how many genes are regulated
8
Q
A
