Chapter 12 Flashcards
Ion channels are typically
Gated
Which ion moves through leak channels
K+
Resting potential of a neuron
Flow of positive and negative ions across membrane is balanced
When Na+ channels open…
Inside cell becomes less negative/ more positive
Patch clamps can be used to observe
Transport of ions through individual ion channels
When an individual ion channels are opened by neurotransmitter binding…
It will flicker between open and closed, but spends more time open when neurotransmitter is bound.
Ion channel that plays role in propagating electrical signals in nerve cells
Voltage gated
When a neuron is stimulated by signal, membrane potential spreads across adjoins regions of plasma membrane by…
Passive spread
What happened to axonal membrane when voltage gated Na+ channels open in a nerve cell?
Depolarization
What helps restore ion gradient across membrane of axon after action potential occured?
Na+ pumps
Role of K+ gated ion channels in action potential
Reverse action potential by repolarizing
Communication between neurons involves the interconversion of electrical to chemical signals
True
At a nerve terminal, how is electrical signal converted to chemical signal?
Voltage gated Ca2+ channels activate causing influx of Ca2+ triggering release of neurotransmitters
How does an inhibitory neurotransmitter (like GABA) make it harder for a postsynaptic cell to depolarize?
Influx of Cl-
How would you block a Ca2+ pump?
Block phosphorylation of conserved asparate in Ca2+ pump
What causes a prolonging of duration of action potential in nerve cells (scorpion venom)
Slowing inactivation of voltage gated Na+ channels
