Chapter 12 Flashcards

1
Q

What does Analgesic mean?

A

Reduce and relives pain

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2
Q

what do we know about Ibuprofen?

A

A good analgesic(reduces and relives pain) and anti-inflammatory and it is the best analgesic on the market.

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3
Q

bright pain is decreased best by?

A

Narcotics (spinal cord).

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4
Q

how does Aspirin decrease body temperature?

A

It normalizes temperature not just decreasing basically.

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5
Q

what do sleep preparation have in them?

A

Antihistamines and Diphenhydramine

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6
Q

What does Antipyretic mean?

A

reduces fever

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7
Q

what drugs are in diet preparations?

A

Stimulants and decongestants

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8
Q

What is the Antipyretic effect

A

(reduces fever) Works on the hypothalamus to increase sweating and dilate peripheral blood vessels.

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9
Q

What is the Anti-coagulant effect?

A

they are blood thinners (stops clotting of blood)
The fact that there is too much bleeding when using aspirin if you are getting surgery.

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10
Q

what decreases dull pain best?

A

Aspirin because it blocks COX

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11
Q

why do we take histamine

A

for the peripheral effect

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12
Q

In pain, what is the neurotransmitter in between hypothalamus and ANS?

A

Prostaglandin

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13
Q

List the three ingredients of cold products.

A
  • Antihistamines
  • Nasal Decongestants
  • Analgesic-Antipyretics (anti fever)
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14
Q

what do monoamine oxides affect?

A

histamine can cause these affects and it can affect mood disorders.

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15
Q

vasoconstriction

A

constriction of blood vessels.

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16
Q

what happens if you dry the mucus too much?

A

Sinus infection

17
Q

what were review panels?

A

What the FDA used to determine if the OTC drugs are safe and effective.

18
Q

decongestants are structurally similar to…

A

Epinephrin and neurotransmitters.

19
Q

how does prostaglandin get produced.

A

COX2 metabolizing arachidonic acid.

20
Q

what does Prostaglandin do?

A

Sends pain signals towards spinal cord

21
Q

what does antihistamines do?

A

dries mucous membranes and creates drowsiness and sedation (think niquil)

22
Q

List three things we know about histamine.

A
  • plays a role in peripheral pain
  • mucous mebrane drier
  • increases Inflammation
23
Q

List the four things we know that Asprin does.

A
  • Analgesic
  • Antipyretic
  • Anti-inflammaotry
  • Anticoagulant
24
Q

What is Rye syndrome

A

the negative affects of a child with a viral infection after they mistakenly take asprinin.

25
Q

explain pain.

A

1) Bradykinin and histamine binds to dermatome
2) Prostaglandin is then allowed to bind to nerves.
3) This allows pain signals to get to the spinal cord.

26
Q

Analgesia

A

blocks prostaglandin synthesis by using COX

27
Q

What determines what kind of pain you experience

A

which peripheral fibers bring signals into the spinal cord.

28
Q

what does Aspirin block?

A

COX

29
Q

who synthesized Asprin

A

Bayler Labs

30
Q

what is Phenacetin and what is its negative possible effects

A

a pain reducer, similar to aspirin but it can cause kidney problems and maybe cancer.

31
Q

what is the active metabolite in phenacetin?

A

Acetaminophen

32
Q

which receptor of histamine does not cross the blood brain barrier?

A

H2