Chapter 11 Flashcards
Define threshold. Why is it difficult to measure?
Minimum quantity of a stimulus that can be detected
Humans are not perfect observers, answer may vary for the same patient
What is a psychometric function?
AKA frequency of seeing (FOS) curve
Range of stimulus intensities tested, percentage of stimulus detected is plotted as a function of stimulus intensity
Compare and contrast the psychometric function for an ideal vs real observer.
Ideal: below the threshold intensity the stimulus is never seen, above this intensity it is always seen
Real: as intensity of stimulus increases, probability of seeing the stimulus increases, there is no clear defines intensity below which stimulus is never seen and above which it is always seen
What is threshold define as in real scenarios.
The intensity that results in detection of the stimulus on 50% of the presentations
What can affect the perception of a stimulus by the visual system?
Stimulus results in neural activity
Random neural noise can affect the stimulus therefore making the threshold variable
May be present in diseased visual system that have more noise (affect VF measurements, peripheral)
(Attention, motivation, and fatigue can also affect threshold)
Describe the methods of ascending limits for threshold measurements. What can negatively affect these results?
Stimulus is initially NOT visible b/c it is below threshold
Trials of stimuli are increased until it is visible (several trials may be averaged together)
Useful for dark adaptometry b/c the state of retinal adaptation is affected minimally by stimulus
May have observer anticipation of stimulus, can help to begin each trial at a different intensity
Describe the method of descending limits for measuring threshold. What is it used to measure clinically? What can it be affected by?
Reverse of ascending
Trial begins with clearly visible stimulus, visibility is decreased systemically until it can no longer be seen
Commonly used to determine visual acuity (big letters to small, threshold MAR is when letters can no longer be resolved)
Affected by observer anticipation, doctor can ensure that patient at least understands the test since they start off by being about to see optotype
Describe forced choice methodology. Who should be setting the threshold criterion?
Encouraging the patient to continue to read down the chart even when they say they can no longer see it
Many patients stop early out of fear that they will be wrong or they just give up (stop once 4 or more mistakes are made)
Practitioner to ensure reliable consistent results (even with bias)
Describe the staircase method of determining threshold.
Combo of ascending and descending
Start with stimulus below threshold and gradually increase until it is seen, reverse and decrease visibility until stimulus cannot be seen, reverse ascending, repeat.
Threshold is taken to be the stimulus intensity at one of the reversals, or average of the last few reversals
Describe the method of constant stimuli for threshold measurement. How can we determine the reliability of the data?
Stimulus visibility is varied randomly from presentation to presentation (blank trials included), FOS curve is plotted based on responses
Patient expectations are kept constant throughout
Number of false positives (report yes during blank)= lax threshold criterion (high false positive)
Number of false negative (report no during stimulus)
Describe the method of adjustment for threshold measurement.
the subject adjusts the stimulus intensity until it is barely visible (or invisible), relatively quick threshold determination
Low repeatability
Describe strict vs lax threshold criterion. How is this resolved?
Strict threshold criterion- donot report unless sure, high threshold low sensitivity
Lax criterion- low threshold, high sensitivity
Vary from observer to observer or trial to trial
Forced choice method
Describe the forced choice method used in threshold determination. What point on the curve shows threshold?
Forcing a choice between several alternatives, one of which contains the stimulus
graph starts at probability of getting the answer correct (50% for 2 choices)
Threshold is assumed to be halfway between chance (lowest) and perfect (100%)
How does more choices affect results of forced choice? How do threshold measurements for this method compare to other methods?
More choices create a steeper curve with less chance of error or estimation
Forces choice usually results in lower threshold, patients do well
What method of threshold measurement is commonly used for infants?
Forces choice