Chapter 104- Hypothyroidism

Question 0

_______ = the hypothalamus responds to an increased output of thyrotropin-releasing hormone (TRH), which triggers pituitary thyrotropin (TSH) secretion. This inturn stimulates thyroid gland enlargement, goiter formation, and thyroid hormone production with preferential synthesis of T3 over T4.

Answer 0

Primary hypothyroidism

Question 1

Hypothyroidism can be divided into _________ those that impairs thyroid function and _________ those that principally involve hypothalamic-pituitary function.

Answer 1

primary hypothyroidism

secondary hypothyroism

Question 2

In _________, the TSH response is inadequate, the gland is normal or reduced in size and both T4 synthesis and T3 synthesis are equally reduced.

Answer 2

Secondary hypothyroidism

Question 3

What are the 3 causes of Primary hypothyroidism?

Answer 3

1. blockade of thyroid TSH receptors
2. impairment of thyroxine production
3. Inhibition of thyroxine release

Question 4

________ = the most common form of hypothyroidism

Answer 4

Hashimoto’s Thyroiditis

Question 5

_______ = *immune mediated injury; may damage all 3 components of glandular formation; the precipitants of excessive antibody production remain ill defined, but TSH receptors and microsomal enzymes (peroxidase) are among the target antigens. Infact *antimicrobial antibodies serve as a convenient laboratory marker for the condition.

Answer 5

Hashimoto’s Thyroiditis

Question 6

_______ = Pathologically a lymphocytic infiltrate and glandular enlarement are noted. Antibodies directed against glandular antigens can impair the response to TSH and the synthesis and release of hormone.

Answer 6

Hashimotos Thyroiditis

Question 7

Although most patients with Hashimoto’s Thyroiditis remain euthyroid, a fracture experience transient ________ because of the premature release of thyroid hormone.

Answer 7

hyperthyroidism