Chap.74-Drugs4HyperCalcemia

Question 0

Therapy for hypercalcemia is optimally directed at reversing the underlying pathophysiology abnormality. Although this principal may seen obvious, it is often overlooked in practice. Thus reversal of hypercalcemia in CANCER is most effectively treated over the LONG TERM by __________.

Answer 0

antineoplastic therapy

Question 1

Correction of hypercalcemia in sarcoidosis is best treated using effective _____.

Answer 1

antisarcoid therapy

Question 2

In general disorders associated with increased intestinal calcium absorption are best treated with _______.
**give 3 examples of these disorders

Answer 2

consuming a low calcium diet and avoiding vitamin D

• Sarcoid
• Milk-alkali syndrome
• 1,25[OH]2D-secreting lymphomas

Question 3

Hypercalcemia in the setting of volume depletion and diminished renal function is best treated by _________.

Answer 3

expanding the ECF volume and GFR with saline and encouraging diuresis with loop diuretics

Question 4

Medication induced hypercalcemia such as by _______, is best treated by how?

Answer 4

thiazide

treat by discontinuation of medication

Question 5

Disorders associated with increased osteoclastic bone resportion, such as _____ and ______, are best treated using inhibitors of bone resorption such as _____,______, and _____.

Answer 5

MAHC & Immobilized hypercalcemia

-biphosphonates, pamidronate or zoledronate

Question 6

Patients with end-stage refractory cancer with severe hypercalcemia may ARGUABLY be best served by _______.

Answer 6

with-holding thearpy

Question 7

Familial hypocalciuric hypercalcemia is treated how?

Answer 7

BEST LEFT UNTREATED!!!!!!!!!