Chapter 10 - Table 10.5 - Documented Herb-Drug interactions

Question 1

Herb - Echinacea

Answer 1

Interacts with: Amiodarone, anabolic steroids, ketoconazole, methotrexate
Effects: Possible increased hepatotoxicity

Question 2

Herb- Feverfew

Answer 2

Interacts with: Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs), heparin, warfarin (Coumadin)
Effects: Increased Bleeding risk

Question 3

Herb: Garlic

Answer 3

Interacts with: Aspirin and other NSAIDs, warfin insulin, oral hypoglycemic agents.
Effects: Increased bleeding risk, additive hypoglycemic effect.

Question 4

Herb: Ginger

Answer 4

Interacts with: Aspirin and other NSAIDs, heparin, warfarin

Effects: Increased bleeding risk

Question 5

Herb: Ginkgo

Answer 5

Interacts With: Anticonvulsants, Aspirin, NSAIDs, Heparin, warfarin, tricyclic antidepressants.
Effects: Possible decreased anticonvulsant effectiveness, increased bleeding potential, possible decreased seizure threshold

Question 6

Herb: Ginseng

Answer 6

Interacts with: CNS depressants, Digoxin (Lanoxin), Diuretics, insulin and oral hypoglycemic agents, warfarin
Effects: Increased sedation, increased toxicity, possible decreased diuretic effects, increased hypoglycemic effects, decreased anticoagulant effects.

Question 7

Herb: Goldenseal

Answer 7

Interacts with: Diuretics

Effects: May decrease diuretic effects

Question 8

Herb: St. John’s Wort

Answer 8

Interacts with: CNS depressants and opioid analgesics, Cyclosporine (Sandimmune), Efavirenz, indinavir, protease inhibitors, selective serotonin reuptake inhibitors, tricyclic antidepressants, warfarin
Effects; Increased sedation, May decrease cyclosporine levels, decreased antiretroviral activity, decreased antiretroviral activity of indinavir, possible serotonin syndrome, decreased anticoagulant effects.

Question 9

Herb: Valerian

Answer 9

Interacts with: barbiturates, benzodiazepines, and other centralnervous system (CNS) depressants
Effects: Increased sedation.