Chapter 10 Blood and Circulatory System Disorder Flashcards
parietal cells can no longer produce hydrochloric acid leading to a low level or absence of acid in the gastric secretions
achlorhydria
clumping of particles
agglutination
loss of muscle control/coordination
ataxia
a reflex adjustment in a small area of a tissue or an organ, which varies depending on the needs of the cells in the area
autoregulation
the balance of the heme component is converted to this then is transported by the blood to the liver where it is conjugated or combined with glucuronide to make it more soluble and then its excreted in the bile
bilirubin
bluish discoloration of the skin and mucous membranes that results from an excessive amount of deoxygenated hemoglobin in the blood or a structural defect in the hemoglobin molecule
cyanotic
the direct cause of this is the lack of vitamin B12
pernicious anemia
deoxygenated hemoglobin, which is dark or bluish-red in color and is found in the venous blood
deoxyhemoglobin
an ameboid action, the movement through an intact capillary wall when they are needed for defensive processes
diapedesis
disorders involving cellular components of blood
dyscrasia
increased effort to breathe
dyspnea
englargement of spleen
splenomegaly
an increase in RBCs that occurs in response to prolonged hypoxia and increased erythropoietin secretion
erythrocytosis
the hormone that originates from the kidney which stimulates erythrocyte production in the red bone marrow in response to tissue hypoxia, or insufficient O2 available to cells
erythropoietin
excess iron can be stored like this
water-soluble and heat resistant up to 75 C
ferritin
less color
hypochromic
inflammation of the oral mucosa and tongue
glossitis
spontaneous hemorrhage into joints eventually causing painful and crippling deformities resulting from recurrent inflammation
hemarthrosis
the proportion of cells (essentially the erythrocytes) in blood and indicates the viscosity of the blood. Male has higher about 42-52% than females 37-48%. An elevated level of this lab indicates dehydration or excess RBC. Low levels of this lab can result from anemia and blood loss.
hematocrit
blood formation. Various blood cells develop from a single stem cell (pluripotential hematopoietic stem cell) during this process is known as
hematopoiesis
destruction of RBCs may cause elevated serum bilirubin levels resulting in jaundice which is the yellow color in the sclera of the eye and skin
hemolysis
removal of blood
phlebotomy
excessive iron can be stored like this in the liver, blood and other body tissues
water-insoluble and thermally denatured
hemosiderin
process of stopping bleeding
- The immediate response of a blood vessel to injury is vasoconstriction of vascular spasm. In small vessels, this decreases blood flow and may allow platelet plugs to form
- thrombocytes tend to adhere to the underlying tissue at the site of injury and if the blood vessel is small, can form a platelet plug in the vessel
- the blood clotting or coagulation mechanism is required in larger vessels by which the clotting factors that are present in inactive forms in the circulating blood are activated through a sequence of reactions
hemostasis
produced to increase certain types of WBCs during an inflammatory response
interleukin
a systemic sign
an increase in WBCs in the circulation often associated with inflammation or infection
leukocytosis
decrease in leukocytes occurs with some viral infections as well as with radiation and chemotherapy
leukopenia
production of WBC is stimulated by colon-stimulating factors (CSFs) produced by cells such as macrophages and T lymphocytes
leukopoiesis
enlarged RBCs contains nuclei
macrocytes
acts as phagocytes with tissue damage occurs
macrophages
causes many forms of anemia
forex. pernicious anemia a common type of megaloblastic anemia is caused by______of vitamin B 12 which is characterized by a lack of intrinsic factor which is needed to absorb B12 in the intestine.
malabsorption
large nucleated red blood cell (RBC) precursors with noncondensed chromatin due to impaired DNA synthesis
megaloblasts
size and shape
morphology
a term used for diseases that involve inadequate production of cells by the bone marrow. exclude disorders such as aplastic anemia and deficiency dyscrasias.
myelodysplastic
such as radiation, industrial chemicals, and drugs that may damage the bone marrow
myelotoxins
a reduction in circulating neutrophils
neutropenia
excessively full of bodily fluid, particularly blood
plethoric
immature non-nucleated RBC
reticulocyte
most common of the blood-clotting disorders and result from deficiencies in the number of circulating platelets
thrombocytopenia