Chapter 10

Question 1

Which one of the following is NOT caused by one of the human papillomaviruses (HPV)?

Answer 1

Molluscum contagiosum

Question 2

Oral mucosal melanoma most commonly arises on the:

Answer 2

hard palate and maxillary alveolar mucosa

Question 3

Which one of the following lesions typically shows squamous metaplasia of the minor salivary gland ducts on microscopic examination?

Answer 3

nicotine stomatitis

Question 4

Squamous cell carcinoma represents approximately what percentage of all oral cancer?

Answer 4

90%

Question 5

HPV would most likely be involved in the pathogenesis of a squamous cell carcinoma in which one of the following locations?

Answer 5

palatine tonsils

Question 6

Which one of the following lesions is LEAST likely to transform into a carcinoma?

Answer 6

seborrheic keratosis

Question 7

Which of the following is the most common site for the melanotic macule?

Answer 7

lower lip vermilion

Question 8

Which strain of HPV has most often been associated with an increased risk of oropharyngeal cancer?

Answer 8

HPV 16

Question 9

A 59-year-old white male presents with a 3 × 3 cm2 ulcerated carcinoma of the buccal mucosa. No evidence of regional or distant metastasis can be identified clinically or radiographically. This lesion is best classified as:

Answer 9

stage II

Question 10

Which one of the following lesions would be most likely to show malignant or dysplastic changes?

Answer 10

erythroplakia of the floor of the mouth

Question 11

Which one of the following benign dermatologic lesions classically presents as a brown, scaly, greasy plaque that appears to be “stuck onto” the skin surface?

Answer 11

seborrheic keratosis

Question 13

Which one of the following is the most common site for intraoral cancer?

Answer 13

lateral border of the tongue

Question 14

By definition, carcinoma in situ is characterized by:

Answer 14

dysplasia involving the entire epithelial thickness, but without invasion

Question 15

In the ABCDE warning signs for melanoma, the “A” stands for:

Answer 15

asymetry

Question 16

The most common form of melanoma is:

Answer 16

superficial spreading

Question 17

Which of the following locations would be the LEAST likely site for squamous cell carcinoma?

Answer 17

midline dorsal surface on tongue

Question 18

The so-called liver spot on the skin is better known as a(n):

Answer 18

actinic lentigo

Question 19

Which one of the following clinical lesions is most likely to become an invasive squamous cell carcinoma?

Answer 19

a 1x1cm^2 leukoplakia in the floor of the mouth

Question 20

Oral squamous cell carcinoma is more common in men. In which of the following locations does squamous cell carcinoma show the most striking male predilection?

Answer 20

lower lip vermilion

Question 21

Oral squamous cell carcinoma is more common in men. In which of the following locations does squamous cell carcinoma show the most striking male predilection?

Answer 21

acanthosis

Question 22

Select the tumor with the worst prognosis.

Answer 22

intraoral melanoma

Question 23

Nicotine stomatitis is most often associated with:

Answer 23

pipe smoking

Question 24

Which one of the following clinical features would be a warning sign for a possible malignant alteration in a pigmented lesion?

Answer 24

a lesion with multiple different colors

Question 25

The prognosis of melanoma of the skin is most closely related to:

Answer 25

depth of invasion

Question 27

Compared to melanoma of the skin, the overall prognosis for oral melanoma is:

Answer 27

much worse