Chapter 1 - Veterinary Pharmacology Flashcards
Pharmacology
The study of how drugs behave in the body
Clinical Pharmacology / Therapeutics
Applying pharmacology to specific treatments
Adverse Drug Reactions (ADRs)
A broader term that includes any adverse reaction either within the therapeutic range (i.e side effect) or as the result of toxic accumulation of the drug.
What are the 4 rules to live by for safe drug usage?
- All drugs are poisons
- No drug is a silver bullet
- All doses are guesses
- Complacency kills
Chemical name
The chemical composition or molecular structure of a drug (mostly used by chemists and pharmacologists)
Nonproprietary / Generic Name
A more concise name given to the specific chemical compound (aspirin, acetaminophen, amoxicillin)
Proprietary / Trade / Brand Name
A unique name a manufacturer gives its particular brand of drug
Generic Equivalents
Drugs produced or marketed by companies other than the original “brand” developer
When a company develops a new drug and has FDA approval, that company has exclusive rights to manufacture this drug for how many years?
In the USA it is 20 years
After the length of time it takes to get a new drug on the market (waiting for a patent), approximately how long will the company have exclusive rights to manufacture their drug?
About 7-12 years
United States Adopted Names Council (USAN)
The body that selects generic drug names
World Health Organization (WHO)
Checks any USAN council names to make sure the selected name isn’t too similar to another drug name used in another country.
FDAs Office of Postmarketing Drug Risk Assessment
Makes sure that the trade name doesn’t sound like any other trade name and that the trade name doesn’t try to convey what the drug claims to do
Extract
A therapeutic agent composed of specially prepared plant or animal parts rather than synthesized chemicals in a laboratory
Bioequivalence
Defined by the FDA as meaning that an equivalent amount of generic drug is absorbed and delivered to the target site within the body compared with the original brant or parent drug (80-125%)
Nutraceuticals (nutritional supplements)
Extracts that are not required to be registered with the FDA - potency of different batches of drug extract may vary. Less expensive, but may not provide a consistent clinical response
OTC drugs
Drugs available for anyone to purchase without a prescription from a doctor
List 3 Veterinary OTC drugs
- Vitamins
- Flea products for use on the surface of the skin
- Dietary supplements
Legend Drugs
Contain ingredients that require greater control of dispensing either because of their toxic effects, potential to be abused or diverted as an illegal substance, or the potential to do harm to the patient or person handling the drug. Limited to dispensing by or upon the order of a licensed prescriber (Vet or Physician)
Veterinary Client Patient Relationship (VCPR)
Legally meaning that the Veterinarian has examined or has adequate medical knowledge of the patient and has agreed to resume responsibility for Veterinary care of the patient
Dosage Form
The description of its physical appearance (typically included in the description and label of the drug)
Name the 3 dosage forms
Solid, Liquid, Semisolid
Name 2 solid dosage form examples
Tablets, capsules
Name 2 liquid dosage forms
Syrups, suspensions, liniments
Name 2 semisolid dosage forms
Gels, ointments, creams, pastes
Tablets
Created by compressing powdered active ingredients and other inert ingredients together to form disc-shaped dosage forms
Excipients
Inert ingredients added to active ingredients that help the tablet perform as it is intended (binders, disintegrants, diluents, flavors, colors)
True or False: Tablets are the same as pills
FALSE.