Chapter 1 - Pharma Intro

Question 0

Agonist

Answer 0

Drug that binds to a receptor and activates a physiologic response or drug action.

Question 1

Adverse Effect

Answer 1

Undesirable and potentially harmful drug effect

Question 2

Antagonist

Answer 2

Drug that binds to a receptor and interferes with other drugs or substances from producing a drug effect

Question 3

Chemical Name

Answer 3

Name that defines the chemical composition of a drug

Question 4

Contraindications

Answer 4

Situations or conditions when a certain drug should not be administered

Question 5

Controlled Substance

Answer 5

Drug that has the potential for abuse and this is regulated by law.

Question 6

Dose

Answer 6

A measurement of the amount of drug that is administered

Question 7

Drug

Answer 7

Chemical substance raft produces a change in body function

Question 8

Drug indications

Answer 8

Intended or indicated uses for any drug

Question 9

ED50

Answer 9

Effective dose 50, or dose that will produce an effect that is 1/2 the maximal response.

Question 10

Generic Name

Answer 10

Nonproprietary name of a drug

Question 11

LD50

Answer 11

Lethal dose 50, or dose that will kill 50% of the laboratory animals tested

Question 12

Mechanism of action

Answer 12

Explanation of how a drug produces it’s effects

Question 13

Nonprescription OTC

Answer 13

A drug that can be purchased without the services of a physician

Question 14

Pharmacology

Answer 14

Study of drugs

Question 15

Potency

Answer 15

Measure if the strength, or concentration, of a drug required to produce a specific effect

Question 16

Prescription Drug

Answer 16

Drug for which dispensing requires a written or phone order that can only be issued by or under direction of a licensed physician

Question 17

Receptor

Answer 17

Specific cellular structure that a drug binds to and that produces a physiologic effect

Question 18

Side Effect

Answer 18

Drug effect other than the theme realistic effect that is usually undesirable but not harmful

Question 19

Site of Action

Answer 19

Ovation within the body where a drug excerpts its therapeutic effect often a specific drug receptor

Question 20

Therapeutic effect

Answer 20

Desired effect to alleviate some condition or symptom of disease

Question 21

Therapeutic Index (TI)

Answer 21

Ration of LD50 to the ED50 in animal studies

Question 22

Toxic Effect

Answer 22

Undesirable drug effect that implies drug poising, can be very harmful or life-threatening

Question 24

Trade Name

Answer 24

Patented proprietary name of a drug sold by a specific drug manufacturer also referred to at the brand name.

Question 25

Pharmacodynamics

Answer 25

Study of the action of drugs on living tissue

Question 26

Pharmacokinetics

Answer 26

Study of the processes of drug absorption, distribution, metabolism, and excretion

Question 27

Pharmacotherapeutics

Answer 27

Study of the use of drugs in treating disease

Question 28

Pharmacy

Answer 28

Science of preparing and dispensing medicines

Question 29

Posology

Answer 29

Study of the amount of drug that is required to produce therapeutic effects

Question 30

Toxicology

Answer 30

Study of the harmful effects of drugs on living Tissues

Question 31

Onset of Action

Answer 31

The time from drug administration to the first observable effect

Question 32

Termination of Action

Answer 32

When the plasma drug concentration falls below the therapeutic range.

Question 33

Time-plasma Drug Concentration Curve

Answer 33

Used for predicting the frequency with which a drug must be administered in order to maintain an effective drug response.
Includes: Onset of Action, Duration of Action, and Termination of Action
Ranges: Toxic Drug Range, Therapeutic Drug Range, Ineffective Drug Range

Question 34

Schedule I

Answer 34

Drugs with high abuse potential and no accepted medical use.

Herion, hallucinogens, MJ, these are not to be prescribed.

Question 35

Schedule II

Answer 35

Drugs with high abuse potential and accepted medical use.
Narcotice (morphine and pure codeine), coke, anphetamines, short-acting barbiturates, nabilone; no refills w/o new prescription

Question 36

Schedule III

Answer 36

Drugs with moderate abuse potential and accepted medical use
Moderate & Intermerdiated acting barbiturates, dronabinol, anabolic steroids, preparations containing codeine plus another drug; prescription required may be refilled 5 times in 6 months with authorization

Question 37

Schedule IV

Answer 37

Drugs with low abuse potential and accepted medical use
Phenobarbital, chloral hydrate, Zolpidem (ambien), antianxiety drugs (valium, librium); prescription required, may be refilled 5 times in 6 months with authorization

Question 38

Schedule V

Answer 38

Druges with limited abuse potential and accepted medical use.
Narcotic drugs used in limited quants for antitussive (codeine) and antidiarrheal purposes; drugs can be sold by a pharmacist; buyer must be 18 yrs. Some States require prescription.

Question 39

1938 Federal Food Drug and Cosmetic Act

Answer 39

Set standards for drug safety. Enacted after 40 patients died from taking an antibiotic that contained dithylene glycol as a solvent.

Question 40

1906 Federal Pure Food and Drug Act

Answer 40

First real drug laws that required drugs to have a minimal standard of strength and purity.
Amended in 1912 to include regulations for labeling and false claims of effectiveness.

Question 41

1962 Amendment to the 1938 Act

Answer 41

Required pharmacological and toxicological research testing in several animal species before a drug could be tested in humans. This act is enforced by the FDA.

Question 42

1970 (Amended in 1990) Federal Comprehensive drug Abuse Prevention and Control Act

Answer 42

The “Controlled Substances Act”. This Act is enforced by the DEA.

Question 43

Teratogens

Answer 43

Drugs that produce birth defects

Question 44

Carcinogen

Answer 44

Drugs that promote the growth of Cancerous tumors

Question 45

Idiosyncrasy

Answer 45

An individual reaction to a drug with an unusual or unexpected response