Chapter 1 - Overview Of Clinical Lab Hematology Flashcards
It is anucleate biconcave cells
RBC
A cell that contains HGB (reddish brown protein)
RBC
RBC is measured to 6-8 ūm in diameter and the zone of pallor covering 1/3 of their center. True or false?
True
He described “worms in blood in 1657
Athanasius Kircher
In 1674 he gave and account of RBC’s
Antok Van Leeuwenhoek
He described platelets as “petites plaques”
Giulio Bizzozero
He developed the Wright stain and opened a new world of visual blood examination through the microscope.
James Homer Wright
The scientific term for cell appearance?
Morphology
Loss of oxygen-carrying capacity and is often reflected in a reduced RBC count is termed?
Anemia
It means, increased RBC count
Polycythemia
When polycythemia occur reflecting in increased RBC mass which condition leads to
Hyperviscosity
To count RBC, a pipetted tiny aliquot of whole blood is needed and mixed it with 0.85% saline. T OR F
T
Dilution for typical RBC count is
1:200
These apparatus are used for manual counting (2)
Hemocytometer and Thoma pipet
Normal hemoglobin transports __ and __
O2 and CO2
Normal types of hemoglobin? (2)
Oxyhemoglobin and deoxyhemoglobin
Oxyhemoglobin contains ___ and ___. And color ____
Oxygen and Hb
Bright red
Carboxyhemoglobin contains __ and __. And color ____
CO2 and Hb
Dark red
Also called as packed cell volume (PCV)
Hematocrit
Hemoglobin measurement. Principle?
Hb(Fe^2+)K3Fe(Cn) -> methemoglobin (Fe^3+) KCn -> Cyanmethemoglobin
What. The. Fuck. Is. This. Shit.
These are abnormal Hgb that transports O2/nonfunctional. (3)
Carboxyhemoglobin - CO + Hb (cherry red)
Methanoglobin - oxidizing agent + Hb (chocolaye brown)
Sulfhemoglobin - invitroreaction (green)
In hematocrit determination. ___ of th capillary tube must be filled
2/3
Capillary tube should be sealed using _____
Clay paraffin
Last immature erythrocyte stage?
Reticulocytes