CHAPTER 1 Introduction to Biochemistry Flashcards
BIOCHEMISTRY
chemistry of the living cell
goal:
* descibe life’s processes at the —- level
* have knowledge of the chemical structures of the participating molecules
* have an understanding of the biologival function of the cellular molecules
molecular
2 Levels of Biochemistry
1. discovering the chemical structures and 3D arrangement of biomolecules
2. defining a language for communication inside cells and organisms; function of molecules
- conformational
- informational
Importance of Biochemistry
- Biochemical studies lead us to the fundamental understanding of life
- Has profound influence on our understanding of vast fields such as medicine, health and nutrition
- BIochemical discoveries advances biotechnology
basic structural and functional unit of life
cell
Cell Theory
1. All organisms are compoesd of one or more cells.
2. The cell is the basic unit of structure and organization in organisms
3. All cells come from pre-existing cells
associated with inventing the first optical telescope and first true compound microscope
Zacharias Jansen
father of microbiology
Anton van Leuwenhoek
coined the term “cell”
Robert Hooke
cells are basic unit of plant life
matthias schleiden
cells are basic unit of animal life
theodor schwann
cells come from pre-existing cells
rudolf virchow
- outer covering of the cell
- composed of phospholipid bilayer, proteins, and carbohydrates
- follows the fluid mosaic model
- ____= collection of carbohydrates
- integral membrane proteins - two-end
- peripheral membrane proteins- one-end
Functions:
1. acts as selectively permeable membrane
2. enables communication with the outside environment
3. maintains constant environment
plasma membrane
glycocalyx
composed of endoplasmic reticulum, golgi, transport vesicles, plasma membrane
cytomembrane system
- series of long canals running throughout the cell with ribosomes attached
- transport proteins to the golgi bodies
rough ER
- tubular in form and lacking ribosomes
- lipid synthesis
- modify molecules, i.e. drugs, pesticides
smooth ER