CHAPTER 1 INTRO TO METABOLISM

Question 1

Metabolism

Answer 1

overall process through which living systems ACQUIRE & USE free energy to carry out their various functions

Question 2

Anabolism

Answer 2

Anabolism –processes primarily concerned with the synthesis (biosynthesis) of complex organic molecules

Question 3

Catabolism

Answer 3

Catabolism –processes related to degradation of complex substances

Question 4

What is the role of metabolism in humans?

Answer 4

To provide warmth and energy for living.
-To supply raw materials for tissue growth and repair.
-To stabilize body weight and compensate for variations in food intake.
To react constructively to pregnancy, injury and disease.

Question 5

CHOs are unsuitable for a long a long-term energy store because:

Answer 5

CHOs are unsuitable for a long a long-term energy store because:
They have excessive bulk, high water content and low energy yield

Question 6

What are the key common molecules?

CATABOLISM

Answer 6

ATP
NAD, FAD
NADP
Acetyl CoA

Question 7

Catabolism (energy?)

Answer 7

Catabolism – generation of free energy (reactions are exergonic)

Question 8

Anabolism (energy?)

Answer 8

Anabolism – utilize free energy (reactions are endergonic)

Question 9

3 Uses of free energy?

Answer 9

1) Mechanical work in muscle contraction and other cellular movements
2) Active transport of molecules and ions
3) Synthesis of macromolecules and biomolecules

Question 10

Metabolic role of ATP

Answer 10

1. Energy currency
2. Allosteric effector
   Concentration of ATP (relative to ADP/AMP) is an index of the energy status of the cell.
   [ATP] determines the rate of reaction of regulatory enzymes

Question 11

Synthesis of 1 mole of ATP under cellular conditions requires

Answer 11

~50kJ

Question 12

What is the Electron donor for reductive biosynthesis?

Answer 12

NADPH

Question 13

NADH/FADH : ?

Answer 13

generation of ATP (catabolic pathways)

Question 14

Thioester bond – high energy bond Go’ -31.5kJ/mol

Answer 14

Part of the free energy obtained from hydrolysis of this bond can be used to drive an endergonic process

Question 15

hydrolysis is a ____ reaction

Answer 15

exergonic