Amino acids and amines DISEASE RELATION

Question 1

Glutamine (amide-N) non-ptn pdt

Answer 1

N3, N9 of purine; N3 of pyrimidine

Question 2

Aspartate non-ptn pdt

Answer 2

N1 of purine; C4, C5, C6 and N1 of pyrimidine

Question 3

Glycine non-ptn pdt

Answer 3

C4, C5 and N7 of purine; phrphyrin and heme

Question 4

Gly, Glu, Cys non-ptn pdt

Answer 4

Glutathione (gamma-glutamylcysteine)

Question 5

Gly, Arg, Met non-ptn pdt

Answer 5

Creatine and creatinine

Question 6

Methionine non-ptn pdt

Answer 6

S-Adenosyl L-Methionine

Question 7

Lys, Met non-ptn pdt

Answer 7

Carnitine

Question 8

Tryptophan non-ptn pdt

Answer 8

Serotonin, melatonin; NAD+

Question 9

Phe, Tyr non-ptn pdt

Answer 9

Thyroid hormones, melanin, dopamine; epinephrine and norepinephrine

Question 10

Histamine

Answer 10

• Dilates capillaries
• Mediator of inflammatory responses
• Stimulates pepsin and acid secretion in stomach

Question 11

GABA

Answer 11

• Neurotransmitter

- Huntington’s disease- Low GABA due to lack of GAD

Question 12

Serotonin

Answer 12

• Vasoconstrictor

- Neurotransmitter

Question 13

Dopamine

Answer 13

• Neurotransmitter

- Parkinson’s disease -low Dopamine in brain

Question 14

Tyramine

Answer 14

-Hypertensive agent