CHAPTER 1: INTRO TO MEDICAL PARASITOLOGY Flashcards
branch of zoology about parasites
Study of host-parasite relationship
study of parasite that infect human
Parasitology
benefits from the other
any organism that lives in or the body of another organism in order to survive.
Parasites/ Parasitos
animal parasite of humans and their medical significance
Clinical Parasitology
association of living organism
Symbiosis
- any organism that harbors parasite
Host
3 SYMBIOSIS TYPES
Mutualism
Commensalism
Parasitism
works together
benefit from each other
association between organisms of different species is benefitted
mutualism
association between individuals of two species in which one species obtain food or benefit from other WITHOUT harming or benefitting the latter
Commensalism
- one organism benefits at expense of parasite usually different species (host)
may lead to injury of host
Parasitism
SIX PRIORITY DISEASES
Leprosy
Leishmaniasis
Trypnosomiasis
Filariasis
Schistosomiasis
Malaria
harboring species, may show no harmful effects or may suffer from various or functional and organic disorders
host
types of host
definitive, intermediate, reservoir, paratenic, accidental, vector
parasites attains sexual maturity
Definitive Host
harbors the asexual or larval stage of the parasite (may or may not be present in the lifecycle)
Intermediate Host
refers to the non-human final host of a parasite.
Necator Americanus
Schistosoma japonicum
Reservoir Host
usually have an ecological function since they can extend the normal host range of the parasite.
paragonimus westermani
Paratenic Host
are those organisms infected or infested by parasite which are not normally associated with them.
Accidental host
not a well-defined type of host, facilitate the transmission of a parasite from one infected host to another susceptibility host.
Mechanical vectors
Biological vectors
vectors
permanent association of two organisms that cannot exist independently.
Symbiosis
4 TYPES OF ASSOCIATIONS:
Commensalism
Mutualism
Parasitism
Phoresy
eating at the same table, neither harmed nor benefited (Shark and remora)
Commensalism
two organism mutually benefiting from each other like termites and flagelattes
Mutualism
includes any reciprocal association in w/c a species depends upon another for its existence
temporary
permanent
Parasitism
(to carry) in which one organism (smaller phoront) is mechanically carried or in another specie (host)
Phoresy
must always be in close contact with the host in order to survive, grow, reproduce, and infect a new host.
Obligatory
capable of reverting from a parasitic to free-living lifestyle and can live with/out the host
strongyloides stercoralis
Facultative
require continuous contact with their host to survive. (endoparasite)
Permanent parasite
associate closely with their host only to feed (ectoparasite)
Temporary (intermittent)
which enter hosts not normally theirs.
do not develop to full maturity (incompatibility)
sometimes establish themselves in their new host for a short period of time (toxocara canis)
Accidental/ Incidental
those which move out of normal habitat within their host ( A. lumbricoides)
Aberrant
organism which are taken in by accident and then passed out harmlessly of an unsuitable host.
Spurious
when parasite is located INSIDE the host refers to any of the internal visceral organs, gastro intestinal tract, RBC
a host parasitized by an __ is said to have an infection or be infected.
endoparasite
examples of endoparasites
Ascaris lumbricoides - lumen of S.I
Plasmodium falciparum - inside the human erythrocytes
when the parasite is located OUTSIDE or on the surface of the host’s body such as the skin or mucous membrane.
a host parasitized by an __ is said to have an infestation or be infeste
ectoparasite
examples of ectoparasites
Pediculus humanus - found on scalp
Sarcoptes scabiel - on the skin
live & multiply in the moist
Capnophilic
example of Capnophilic
protozoans
lives in RBCS
hematozoic
example of hematozoic
malaria
lives inside the cell
cytozoic
example of cytozoic
(tissues isospara hominis)
live in body cavities
Coelozoic
example of Coelozoic
(mansorella perstans)
- live inside lumen of intestine
Enterozoic
forever parasite; lives in a single host
Permanent parasite
larval stage is different from adult stage
Periodic
- fix in an unusual habitat
Erratic
example of obligatory relationship
ascaris lumbricoides
example of facultative relationship
threadworm
example of intermittent relationship
mosquito
infects individual with underlying disease
Opportunistic
Soil transmitted (4)
ascaris lumbricoides
trichuris trichuria
hookworms
strongyloides stercoralis
Arthropod/ Vector transmitted (5)
malaria/ filarial worms
leishmania
trypanosomes
babesia
schistosome spp
Food borne
taenia spp
trichenella spiralis
toxoplasma gondii
capillaria philippinensis
heterophyds
paragonimus westermanii
fasciolid
Waterborne
amoeba
giardia lamblia
blastocytosis hominis
cryptosporidum spp
Cyclospora cayetanensis
Sexual Intercourse -
trichomonas vaginalis
Inhalation of air-borne eggs -
enterobius vermicularis
Congenital transmission -
T. gondi
Skin penetration -
Hookworm, S. Stercoralis
a parasite that lives within a single host during the entire life cycle
Monoxenous
a parasite that lives within more than one host during entire life cycle
Heteroxenous
hermaphrodites; have complete set of sex organs
Monoecious
sexes are separated
Dioecious
TISSUE ASPIRATES
Liver
amoeba
TISSUE ASPIRATES
Duodenal
strongy/giardia
TISSUE ASPIRATES
Lymph nodes
leishmania, american trypanosomes
TISSUE ASPIRATES
CSF
africa trypanosomes
TISSUE ASPIRATES
Hydrocoele
microfilaria of bancrofti
TISSUE BIOPSY
muscle
T. spiralis
TISSUE BIOPSY
rectal
schistosomes
TISSUE BIOPSY
lymph node
filarial worm
TISSUE BIOPSY
skin
leishmaniasis
occurrence and prevalence of disease
study the manner of spread of contagious disease
Epidemiology
sudden inc. of infection
Epidemic
certain infection present in low nos. but constantly present in the area
Endemic
disease which spreads to severeal countries and affects a large number of people
pandemic
allowing them to metabolize the nutrients from the host and store these for energy production
enzymatic action
depriving the host of essential nutrients
Spollative action
causes massive Intestinal bleeding (IDA)
Hookworm
competes with its host Vit B12 (M. anemia)
D. latum
possession of sickle-cell trait may confer some protection
P. falciparum
presence of duffy blood factor increase the susceptibility of infections
P. vivax
study of patterns, distribution, and occurrence of disease
Epidemiology
no. of new cases of infection appearing in a population in a given period of time
Incidence
is the number os individuals in a population estimated species at a given time
Prevalence
percentage of individuals in a population infected with atleast one parasite
Cumulative prevalence
- refers to the no. of worms per person
Intensity of Infection
STAGES IN LIFE CYCLE
Ovum
Egg
Embryo
Larva
Trophozoite
Cyst
refers to practical measure that stop transmission cycle from the very root of its cause
prevention
refers to the proportion of target population reached by an intervention
Coverage
is a genetically transmitted loss of susceptibility to a drug in worm population that was previously sensitive to the appropriate therapeutic dose
Drug resistance
is the effect of a drug against an infective agent in ideal experimental conditions and isolated from any context
Efficacy
is a measure of the effect of a drug against an infective agent in a particular host
Effectiveness
- is the use of anthelminthic drugs in an Individual or PH program
Deworming
refers to the no. of previously positive subjects found to be agg negative on examination of a stool
Cure rate
is the % fall in egg counts after deworming based on examination of a stool
Egg reduction rate
Individual-level deworming with selection for treatment based on a diagnosis of infection
Selective treatment
group-level deworming where the group to be treated may be defined by age, ge, sex or social characteristics irrespective of infection status
Targeted treatment
population-level deworming in w/c the community is treated irrespective of age, sex, infection status or other social characteristics
Universal treatment
requires specific snail Intermediate host and condition that ensure host-parasite contact
trematodes
__, can burrow into the mud, shielding itself from various molluscicides
Snail Ih of Schistosoma
is the causative agent of one type of malaria In w/c the vector is a female mosquito of the genus Anopheles
P. falciparum
causes mucocutaneous leishmaniasis - transmitted by sandflies.
Leishmania braziliensis