chap 3 transmission Flashcards

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1
Q

resting membrane potential

A

difference in charge between inside and outside of neuron at rest

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2
Q

Electrical value of RMP

A

-70mv

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3
Q

Why is RMP -70mv

A

difference in concentration of sodium and potassium ions across the membrane

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4
Q

Is sodium or potassium more permeable to the membrane

A

potassium

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5
Q

Types of pressure on NA to enter the cell

A

electrostatic and concentration gradient

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6
Q

Why does NA not succumb to pressure and enter the cell

A

1) At rest K channels are open and NA are closed
2) more K channels than NA channels
3) Na-K pump , 3 Na out, 2 K in

This maintains -70mv

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7
Q

What is an action potential

A

brief reversal in membrane potential caused by Na rushing into cell making it positive

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8
Q

Action potentials travel ____ through nodes of Ranvier (gaps in myelin), and ____ in myelinated areas

A

Actively, passively

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9
Q

Action potentials are not graded , T/F

A

T- Action potentials are all or nothing

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10
Q

What does it mean to say that an action potential is non decremental

A

it does not lose strength as it travels

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11
Q

What causes hyperpolarization

A

K ions rushing out of cell, membrane goes below resting potential

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12
Q

What is a postsynaptic potential

A

Pulse that occurs within cell body as result of activity in neighboring cells

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13
Q

What are the two types of PSP

A

Excitatory and inhibitory

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14
Q

What happens when sum of PSP’s reach threshold

A

action potential

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15
Q

Batrachotoxin is a toxin, secreted by poison arrow frogs, that selectively interferes with _______ channels.

A

sodium

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16
Q

A brief period of complete insensitivity to stimuli

A

absolute refractory period

17
Q

When the interior of the neuron becomes less negative, it is said to be

A

depolarized

18
Q

When the interior of the neuron becomes even more negative, it is said to be

A

hyperpolarized

19
Q

A receptor protein that includes an ion channel that is opened when the correct neurotransmitter attaches to the receptor

A

Ionotropic

20
Q

When a NT binds to this type of receptor, a G protein is activated and this alters the functioning of the postsynaptic cell

A

metabotrophic

21
Q

most prevalent excitatory NT in mammals

A

glutamate

22
Q

contributing to un equal dist of ions on either side of resting neural mem

A

na k pump

23
Q

what is correct seq of NT release

A

synthesis storage exocytosis reiptake

24
Q

compared to metab receptors, ionotropic produce effects that are

A

less diffuse and develop rapidly

25
Q

plays a role in reducing excess nt release

A

autoreceptors