Chap 1,2,3,4 Flashcards
Normal Gestational Period
40 weeks, 9 months (3 trimesters of 3 mo.each)
Considered neonate
delivery to 1 month
Considered infant
1 month to 1 year
considered child
after 1 year
Stages of lung development
Embryonic 26-52 days
Pseudoglandular 52 days-16 weeks (structure)
Canalicular 17 - 26 weeks (I and II alveolar cells)!!
Saccular 26-36 weeks
Alveolar 36 weeks - term
I and II alveolar cells made when
17-26 weeks
Pulmonary hypoplasia
*hypoplastic lung
Underdeveloped lung tissue
Failure of the lungs to develop
Main cause of pulmonary hypoplasia
Diaphragmatic hernia: diaphragm is seperated and bowels are in thoracic cavity. Compresses lung tissue and it cannot develop adequately
Surface tension
mutual attraction of the like molecules for one another
Principle of La Place’s law as
the radius of a buble decreases the surface tension increases
soo.. a small alveoli has more surface tension and is more difficult to inflate than a large alveoli
Surfactant
a phospholipid found on the alveolar walls that lowers surface tension
- it increases compliance
- helps prevent alveolar collapse
- is produced by type II alveolar cells
- appears at approx 23-26 weeks gestation
Fetal lung fluid
20-30 ml/kg of body wt
-volume equivalent to FRC
Function of fetal lung fluid
maintain airway patency
-formation, size, and shape of air spaces
Evaluation of lung fluid
1/3 squeezed out during delivery
-the remaining fluid is absorbed by lymphatic system
lung fluid retention after C-section
transient Tachypnea of the newborn (passes fast)
What is the first major organ to develop
heart, pumps blood in 8 weeks
Which one is higher Venous or Arterial pressure
Venous pressure is higher than arterial, Right heart is stronger than left heart (opposite of us)
- High PVR
- Low placental resistance to blood flow - gets O2 from mother and rids of CO2
THREE FETAL SHUNTS
- ductus venosus- belly button
- Foramen Ovale- Hole between right and left atria
- Ductus arteriosus
Path of fetal blood flow
Placenta- umbilical vein- ductus venosus - inferior vena cava - right atrium_>
(a) Foramen ovale - left atrium - left ventricle - aorta- brain (the most oxygenated blood)
(b) Right ventricle- pulmonary artery - ductus arteriosus - aorta- body
(C) Right Ventricule - P.A. - lungs - left atrium (about 10% of the total blood supply)
Intrauterine structures
Placenta, Umbilical cord
Placental Structure
Chorionic villi exchanges the gases and nutrients from mom to fetus
Umbilical cord structure!!!
2 umbilical arteries, 1 umbilical vein, Whartons jelly
Stages of labor
Stage 1: onset of first true contraction to complete dilation and effacement
Stage 2: full dilation and effacement to delivery of the fetus
Stage 3: Expulsion of the placenta
Normal position during labor
Baby head down= vertex position
Initiation of the first breath
- Asphyxia= CO2 increases, PaO2 decreases
- Recoil of the thorax
- Environmental changes
First breath may require what pressure
-100cmH2O, less pressure needed as FRC is established
Change from fetal to adult circulation
- Clamp umbilical cord removes placenta from arterial circulation increases arterial pressure
- lung fluid replaced with air
PaO2 increaes, PaCO2 decreases -> Pulmonary vasodilation (PVR decreaess) - Closure of shunts
Closure of shunts
D.V. - no blood flow
F.O. - pressure changes (increase left atrial pressure)
D.A. Increase PaO2 -> Decrease prostaglandins -> constricts smooth muscle around D.A.
Factors identifying a high-risk pregnancy
Preterm birth, less than 37 weeks gestation
Alcohol
Smoking
Cocaine
Hypertension (preclampsia)
Diabetes
Infection: herpes simplex, Hep B, HIB, Group B streptococcus
Placental abnormalitites
Placenta previa- may be partial or total (covered placenta)- might need C section
Placental abruption- Premature separation of the placenta from the uterine wall
Umbilical Cord problems
Cord compression
Prolapse (comes out first)- leading to cord compression
Nuchal (around neck)