Ch.7 Membrane Structure and Function Flashcards
Selective Permeability
A property of biological membranes that allows them to regulate the passage of substances across them
Amphipathic
Having both a hydrophilic region and a hydrophobic region
Fluid Mosaic Model
The currently accepted model of the cell membrane structure, which envisions the membrane as a mosaic of protein molecules drifting laterally in a fluid bilayer of phospholipids
Effect of Cholesterol at High Temps.
Cholesterol makes the membrane less fluid by restraining phospholipid movement (since it is wedged between phospholipid molecules in the plasma membrane)
Effects of Cholesterol at Low Temps.
Since cholesterol hinders the close packing of phospholipids, it lowers the temp. required for the membrane to solidify
Integral Proteins
A transmembrane protein w/hydrophobic regions that extend into and often completely span the hydrophobic interior of the membrane and w/hydrophilic regions in contact w/the aqueous solution on one or both sides of the membrane (or lining the channel in the case of a channel protein)
Peripheral Protein
A protein loosely bound to the surface of a membrane or to part of an integral protein and not embedded in the lipid bilayer
Integrins
A type of integral transmembrane protein
Six Major Functions Performed by Proteins
Transport, enzymatic activity, signal transduction, cell-cell recognition, intercellular joining, and attachment to the cytoskeleton and ECM
Transport Function of Proteins
A protein that spans the membrane may provide a hydrophilic channel across the membrane that is selective for a particular solute